6625-35-0

Upstream product

• 701-57-5 1-methylthio-4-nitro-benzene 
• 96-32-2 bromoacetic acid methyl ester 
• 2365-48-2 Methyl thioglycolate 
• 100-00-5 4-chlorobenzonitrile 
• 1849-36-1 para-nitrobenzenethiol 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 350-46-9 4-Fluoronitrobenzene 
• 198836-35-0 (S)-2-(4-nitrobenzenesulfonylamino)-3-methyl-butyric acid methyl ester 
• 20455-07-6 p-nitrophenyl methanesulfonate 
• 96-34-4 methyl chloroacetate 
• 67-56-1 methanol 
• 3406-75-5 2-(4-nitrophenylthio)acetic acid 

Downstream Products

• 4346-49-0 potassium p-nitrobenzenesulfonate 
• 1314020-62-6 4-[(4-nitrophenyl)sulfonyl]tetrahydro-2H-pyran-4-carboxylic acid 
• 1314020-63-7 4-[(4-aminophenyl)sulfonyl]tetrahydro-2H-pyran-4-carboxylic acid 
• 1314020-64-8 4-[(4-azidophenyl)sulfonyl]tetrahydro-2H-pyran-4-carboxylic acid 
• 1314020-65-9 4-[(4-azidophenyl)sulfonyl]-N-(tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-4-carboxamide 
• 1314020-67-1 4-[(4-azidophenyl)sulfonyl]-N-hydroxytetrahydro-2H-pyran-4-carboxamide 
• 1314020-68-2 N-hydroxy-4-({4-[(4-phenoxyphenyl)-1H-1,2,3-triazole-1-yl]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide 
• 1314020-69-3 N-hydroxy-4-({4-[4-(4-methylphenyl)-1H-1,2,3-triazole-1-yl]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide 
• 1314020-71-7 N-hydroxy-4-({4-[4-(4-pentylphenyl)-1H-1,2,3-triazole-1-yl]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide 
• 1314020-72-8 N-hydroxy-4-({4-[4-(4-pentylbenzyl)-1H-1,2,3-triazole-1-yl]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide 
• 1314020-73-9 N-hydroxy-4-{[4-(4-phenyl-1H-1,2,3-triazole-1-yl)phenyl]sulfonyl}tetrahydro-2H-pyran-4-carboxamide 
• 1314020-74-0 N-hydroxy-4-{[4-(4-biphenyl-4-yl-1H-1,2,3-triazole-1-yl)phenyl]sulfonyl}tetrahydro-2H-pyran-4-carboxamide 
• 1314020-75-1 N-hydroxy-4-({4-[4-(4-methoxyphenyl)-1H-1,2,3-triazole-1-yl]-phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide 
• 1314020-76-2 4-{[4-(4-butyl-1H-1,2,3-triazole-1-yl)phenyl]sulfonyl}-N-hydroxytetrahydro-2H-pyran-4-carboxamide 

Relevant academic research and scientific papers

Sulfoxide Reduction/C(sp3)-S Metathesis Cascade in Ionic Liquid

A sulfoxide reduction/C-S bond metathesis cascade between sulfoxides and alkyl bromides has been developed to access high-value sulfides without the use of any catalysts or bases. In this cascade, classical Kornblum oxidation is employed to reduce sulfoxides with alkyl bromides in ionic liquid. This protocol features high functional tolerance, mild conditions, promising scalability, and sustainable solvents.

Facile synthetic approaches to 1-thiocyclopropanecarboxylates

Two facile synthetic approaches to the novel biologically interesting 1-thiocyclopropanecarboxylates starting from corresponding thiols were developed. Approach A involved five steps with the key steps being the SN2 reactions of thiols and α-br

NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVES AND USE THEREOF

The present invention relates to a novel amino-phenyl-sulfonyl-acetate derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating diabetes comprising the same as an active ingredient.

Continuous flow biocatalytic resolutions of methyl sulfinylacetates

Product inhibition was encountered for some substrates in the resolution of methyl sulfinylacetates mediated by lipase Amano AK, so an apparatus to continually extract the carboxylate product was devised. This was applied to resolve some sulfoxides with h

Potent "clicked" MMP2 inhibitors: Synthesis, molecular modeling and biological exploration

A new series of MMP2 inhibitors is described, following a fragment-based drug design approach. One fragment containing an azide group and a well known hydroxamate Zinc Binding Group in a α-sulfone, α-tetrahydropyrane scaffold, has been synthesized. Water-

N-Nosyl-α-amino acids in solution phase peptide synthesis

A highly efficient and practical synthesis of peptides in solution phase has been developed. The procedure is based on the use of p-nitrobenzenesulfonyl (nosyl) group for the protection of the amino function of α-amino acids. Every step of the procedure,

New procedure for nucleophilic sulfonation of aromatic nitro compounds: Destructive oxidation of S-arylthioglycolic acids esters

A new reaction was discovered: oxidative destruction of sulfides of ArSCH2CO2Me type to sulfonic acids ArSO3H effected by 70% HNO3. This reaction was used to introduce an SO 3H group instead of aromat

Selective introduction of sulfo groups into aromatic nitro compounds

A new reaction has been found, viz. oxidative destruction of nitro-substituted sulfones ArSO2CH2CO2Me to give sulfonic acids ArSO3H on treatment with 70% HNO3; in addition, di(arylsulfonyl)furoxans ar

Sulfonyl Esters. V. A Preparation of Dichloromethyl Sulfones

α-Sulfonyl methyl esters have been chlorinated in the presence of base.Chlorination proceeds with accompanying demethoxycarbonylation to furnish dichloromethyl sulfones in good yields.