66494-26-6

Basic information

• Product Name: Methyl 1-(tert-butoxycarbonylaMino)cyclopropanecarboxylate
• Synonyms: Methyl 1-(tert-butoxycarbonylaMino)cyclopropanecarboxylate;Cyclopropanecarboxylic acid, 1-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester;Methyl 1-(Boc-aMino)cyclopropanecarboxylate;methyl 1-((tert-butoxycarbonyl)amino)cyclopropane-1-carboxylate
• CAS NO: 66494-26-6
• Molecular Formula: C₁₀H₁₇NO₄
• Molecular Weight: 215.24628
• Mol File: 66494-26-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 290.5±19.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10.79±0.20(Predicted)
• CAS DataBase Reference: Methyl 1-(tert-butoxycarbonylaMino)cyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 1-(tert-butoxycarbonylaMino)cyclopropanecarboxylate(66494-26-6)
• EPA Substance Registry System: Methyl 1-(tert-butoxycarbonylaMino)cyclopropanecarboxylate(66494-26-6)

Safety Data

• Hazardous Substances Data: 66494-26-6(Hazardous Substances Data)

Usage

General Description

Methyl 1-(tert-butoxycarbonylamino)cyclopropanecarboxylate is an organic compound that is used primarily in the field of chemistry. It is a reagent utilized in various processes due to its chemical properties. This chemical is known for the presence of the precious cyclopropane ring in its structure, which adds to its reactivity. Furthermore, it features a tert-butoxycarbonyl group - commonly used as a temporary protecting group for amines - and a carboxylate group that makes the molecule a potential intermediate in the synthesis of a wide variety of organic compounds. Despite its complex name, it serves as a key component in multiple synthetic pathways.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 72784-42-0 methyl 1-aminocyclopropane-1-carboxylate hydrochloride 
• 88950-64-5 1-<(tert-butyloxy)carbonylamino>cyclopropane-1-carboxylic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 113020-21-6 1,1-cyclopropanedicarboxylic acid monomethyl ester 
• 75-65-0 tert-butyl alcohol 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 333-27-7 methyl trifluoromethanesulfonate 
• 308266-24-2 (N-tert-butoxycarbonyl)-1-(benzyloxymethyl)cyclopropylamine 
• 107017-73-2 tert-butyl (1-(hydroxymethyl)cyclopropyl)carbamate 
• 186581-53-3 diazomethane 

Downstream Products

• 107017-73-2 tert-butyl (1-(hydroxymethyl)cyclopropyl)carbamate 
• 107017-74-3 (1-((tert-butoxycarbonyl)amino)cyclopropyl)methyl methanesulfonate 
• 72784-42-0 methyl 1-aminocyclopropane-1-carboxylate hydrochloride 
• 922337-18-6 methyl 1-[benzyl(tert-butoxycarbonyl)amino]cyclopropanecarboxylate 
• 861648-80-8 tert-butyl (1-((3,5-dichlorophenyl)carbamoyl)cyclopropyl)carbamate 
• 861648-81-9 tert-butyl [1-(3,5-dichlorophenylaminomethyl)cyclopropyl]carbamate 
• 88950-64-5 1-<(tert-butyloxy)carbonylamino>cyclopropane-1-carboxylic acid 

Relevant articles and documents

SUBSTITUTED TRIAZINONES AS THYROID HORMONE RECEPTOR AGONISTS

The application relates to a compound of Formula (I') or (I), or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of thyroid hormone receptors, a pharmaceutical composition comprising a compound of Formula (I') or (I), and a method of treating or preventing a disease or disorder regulated by thyroid hormone.

SUBSTITUTED 1,2-DIHYDRO-3H-PYRROLO[1,2-C]IMIDAZOL-3-ONE ANTIBACTERIAL COMPOUNDS

The invention relates to antibacterial compounds of formula (I) wherein M is one of the groups MA, MB and MC represented below wherein R1, MA, MB and MC are as defined in the specification; and to salts thereof.

Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them

Compounds of formula (I): wherein: n represents an integer of from 1 to 6 inclusive, X represents an oxygen atom or an NR6 group, Y represents a carbon atom or a nitrogen atom,Z represents a carbon atom or a nitrogen atom,R1 and R2 represent a hydrogen atom or an alkyl or arylalkyl group,R3 and R4 represent a hydrogen atom or an alkyl group, R5 represents a hydrogen atom or an alkyl, halogen, hydroxy, alkoxy, cyano, nitro, acyl, alkoxycarbonyl, trihaloalkyl, trihaloalkoxy or optionally substituted amino group, R6 represents a hydrogen atom or an alkyl or arylalkyl group,Ra, Rb, Rc, Rd and Re are as defined in the description. Medicinal products containing the same which are useful as specific nicotinic ligands of α4β2 receptors.