66530-18-5

Usage

Molecular weight

466.43 g/mol

Structure

A derivative of glucose with benzoyl groups substituted at the 2, 3, 4, and 6 positions

Type

Chemical compound

Usage

Commonly used as a chemical intermediate in organic synthesis

Production

Often used in the production of glycosides, which have potential therapeutic activities in the pharmaceutical industry

Application

Utilized in carbohydrate chemistry for the protection and manipulation of glucose derivatives

Versatility

Has a range of applications in research and industry due to its reactivity in organic synthesis.

Upstream product

• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-α-D-mannopyranoside 
• 7296-15-3 alpha-D-mannopyranoside 
• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-β-D-mannopyranose 
• 41308-76-3 allyl α-D-mannopyranoside 
• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-β-D-glucopyranose 
• 22415-91-4 1,2,3,4,6-penta-O-benzoyl-α-D-glucopyranose 
• 14218-11-2 2,3,4,6-tetra-O-benzoylglucosyl bromide 
• 592-04-1 mercury(II) cyanide 
• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-D-glucopyranoside 
• 105376-04-3 ethyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside 
• 98-88-4 benzoyl chloride 
• 492-62-6 alpha-D-glucopyranose 
• 1435780-53-2 allyl 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside 
• 7464-56-4 1-O-allyl-α-D-glucopyranoside 

Downstream Products

• 131166-76-2 triethylammonium 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl hydrogenphosphonate 
• 14726-07-9 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl iodide 
• 278800-64-9 dihydrocholesteryl-2,3,4,6-tetra-O-benzoyl-α-D-mannopyranoside 
• 183901-63-5 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate 
• 1218904-60-9 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl-N,N,N',N'-tetraisopropylphosphorodiamidite 
• 865470-38-8 3-butenyl 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranoside 
• 125367-09-1 n-pent-4-enyl 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranoside 
• 1477511-05-9 C₄₅H₄₀NO₁₁P 
• 121523-91-9 1-O-acetyl-2,3,4,6-tetra-O-benzoyl-β-D-glucopyranose 
• 112841-30-2 1-O-acetyl-2,3,4,6-tetra-O-benzoyl-α-D-glucopyranose 
• 231284-48-3 N-(2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)piperidine 
• 231284-49-4 N-(2,4,6-tri-O-benzoyl-β-D-glucopyranosyl)piperidine 
• 231284-50-7 N-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)piperidine 
• 14262-85-2 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranosyl iodide 

Relevant academic research and scientific papers

Carbon tetrachloride-free allylic halogenation-mediated glycosylations of allyl glycosides

The allylic bromination of allyl glycosides is conducted using NBS/AIBN reagents in (EtO)2CO and PhCF3 solutions, without using CCl4 as a solvent. The activated mixed halo-allyl glycosides led to glycosylations, mediated by a triflate, in a latent-active

GLUCOSE-RESPONSIVE INSULIN CONJUGATES

Glucose-responsive insulin conjugates that contain one or more trisaccharides are provided. Such insulin conjugates may display a pharmacokinetic (PK) and/or pharmacodynamic (PD) profile that is responsive to the systemic concentrations of a saccharide such as glucose or alpha-methylmannose, even when administered to a subject in need thereof in the absence of an exogenous multivalent saccharide-binding molecule.

Delta-oleanolic acid saponin compound and medical application thereof

The invention discloses a delta-oleanolic acid saponin compound and medical application thereof. The delta-oleanolic acid saponin compound is a compound with a structural formula shown as a formula (I), and pharmaceutically acceptable salt or ester or pro

Lewis acid promoted anomerisation of alkyl O- and S-xylo-, arabino- and fucopyranosides

Pentopyranoside and 6-deoxyhexopyranosides, such as those from D-xylose, L-arabinose and L-fucose are components of natural products, oligosaccharides or polysaccharides. Lewis acid promoted anomerisation of some of their alkyl O- and S-glycopyranosides i

Glycosylation with 3,5-Dimethyl-4-(2′-phenylethynylphenyl)phenyl (EPP) Glycosides via a Dearomative Activation Mechanism

A highly effective and versatile glycosylation method is developed, which uses 3,5-dimethyl-4-(2′-phenylethynylphenyl)phenyl (EPP) glycosides as donors and NIS/TMSOTf as promoter and proceeds via an unprecedented dearomative activation mechanism.

The dehydroepiandrosterone and dehydroepiandrosterone alkone glycosylation derivative and its preparation method and application

The invention discloses epiandrosterone glycosylation derivatives and dehydrogenated epiandrosterone glycosylation derivatives, and a preparation method thereof. The preparation method comprises the following steps: respectively carrying out coupling reac

3-(Dimethylamino)-1-propylamine: A cheap and versatile reagent for removal of byproducts in carbohydrate chemistry

Inexpensive 3-(dimethylamino)-1-propylamine (DMAPA) was found to be effective in anomeric deacylation reactions giving 1-O deprotected sugars in high yield as precursors for the formation of imidate glycosyl donors. DMAPA was also found to be useful for removing excess reagents such as benzoyl chloride, tosyl chloride, and 2,2,2-trifluoro-N-phenylacetimidoyl chloride. The deacylation reaction could be conducted in moist THF and did not require chromatographic purification since an acidic wash was sufficient to remove excess reagent and the formed byproduct.

2′-Deoxy-2′,2′-difluorothymidine analogues for radiolabeling with fluorine-18 and other biomedical applications

Novel 2′-deoxy-2′,2′-difluorothymidine analogues with potential applications as antiviral, cytotoxic and cancer imaging agents have been synthesized. Introduction of the hydroxymethyl functionality at the 5-position of 2′-deoxy-2′,2′-difluoruridine provided a key intermediate with a suitable synthetic handle for the generation of these nucleoside derivatives.

TIMOSAPONIN COMPOUNDS

Provided herein are timosaponin compounds of Frmula I, II, IIΙ, I', II' and IIΙ', pharmaceutical compositions comprising the coumpounds, and processes of preparation thereof. Also provided are uses of said timosaponin compounds for preparing medicament for the treatment of diseases associated with beta-amyloid in hosts or subjects in need thereof.

Cross metathesis assisted solid-phase synthesis of glycopeptoids

A solid-phase synthesis of glycopeptoids was explored through olefin cross metathesis (CM). Peptoids and sugar derivatives with appropriate olefin moieties were coupled in the presence of an olefin metathesis catalyst to afford glycopeptoids in good yield