6725-34-4

Upstream product

• 538-51-2 benzylidene phenylamine 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 100-52-7 benzaldehyde 
• 16302-98-0 petivericin 
• 98909-99-0 [(4-Chloro-phenyldisulfanyl)-phenyl-methyl]-trimethyl-silane 
• 75102-43-1 3-Methyl-2-phenylthiazolidine-4,5-dione 
• 108-91-8 cyclohexylamine 
• 81214-74-6 2,4-Diphenyl-1,3-dithietan 
• 135581-63-4 5-uracilylmethylenepyridinium chloride 
• 100-53-8 phenylmethanethiol 
• 100-46-9 benzylamine 
• 16721-45-2 triphenyl(phenylmethylene)phosphorane 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 110-86-1 pyridine 

Downstream Products

• 932-90-1 syn-benzaldehyde oxime 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 84040-18-6 3,4-dimethyl-6-phenyl-5,6-dihydro-2H-thiopyran 
• 150-60-7 dibenzyl disulphide 
• 121-68-6 dithiobenzoic acid 
• 7664-93-9 sulfuric acid 
• 100-52-7 benzaldehyde 
• 65-85-0 benzoic acid 
• 588-59-0 stilbene 
• 1884-68-0 tetraphenylthiophene 
• 92825-03-1 2,4-diphenyl-4H-naphtho<1,2-d><1,3>thiazine 
• 92825-04-2 2,4-diphenyl-1,4-dihydro-2H-naphtho<1,2-d><1,3>thiazine 
• 5373-55-7 N-(4-methylphenyl)thiobenzamide 
• 857168-08-2 mercapto-phenyl-acetonitrile 

Relevant academic research and scientific papers

Heterometallic coordination polymers: syntheses, structures and heterogeneous catalytic applications

A metalloligand Na[Co(L1)2] (1) of the ligand H2L1 (N2,N6-bis(4,5-dihydrothiazol-2-yl)pyridine-2,6-dicarboxamide) offering appended thiazoline rings has been used for the synthesis of one-dimensional {Co3+-Zn2+} (2), {Co3+-Cd2+} (3) and {Co3+-Hg2+} (4) coordination polymers. 1 offers appended thiazoline rings having both soft sulphur and hard nitrogen donors. The crystal structures of 2 and 3 display the coordination of hard thiazoline-N donors to Zn2+ and Cd2+ ions. Interestingly, 4 illustrates the bonding through both hard thiazoline-N and soft thiazoline-S donors. The three heterometallic coordination polymers have been used as reusable heterogeneous catalysts for the ring-opening reactions of oxiranes and thiiranes; Knoevenagel condensation of benzaldehydes and benzothialdehydes; and cyanation reactions of aldehydes and carbothialdehydes. Our results demonstrate that the relative size and Lewis acidity of secondary metals potentially control the catalytic outcome via preferential interaction with the substrates.

ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS

The present invention relates to ligation agents and their use in making an amide ligation product. Methods of making the ligation agents are also disclosed.

The oxidation of thiols by flavoprotein oxidases: A biocatalytic route to reactive thiocarbonyls

Flavoprotein oxidases are a diverse class of biocatalysts most of which catalyze the oxidation of C-O C-N or C-C bonds. Flavoprotein oxidases that are known to catalyze the oxidation of C-S bonds are rare being limited to enzymes that catalyze the oxidative cleavage of thioethers. Herein we report that various flavoprotein oxidases previously thought to solely act on alcohols also catalyze the oxidation of thiols to thiocarbonyls. These results highlight the versatility of enzymatic catalysis and provide a potential biocatalytic route to reactive thiocarbonyl compounds which have a variety of applications in synthetic organic chemistry.

Reactions of Hexamethyldisilathiane with Silyl Acetals: A General Access to Thioformylsilanes

Reaction of several silylated acetals with hexamethyldisilathiane (HMDST) in the presence of CoCl2·6H2O affords a simple, novel and general entry to thioformylsilanes, directly trapped in situ as their Diels-Alder cycloadducts.

Synthesis of indole, benzofuran and benzothiophene by pyrolysis of 2-anilinoethanol, 2-phenoxyethanol and 2-(phenylthio)ethanol acetates

The synthesis of indole is possible by pyrolysis of compounds of the general formula : ΦNHCH2CH2X. The pyrolysis of the acetates (X = OCOCH3) of 2-anilinoethanol 3a, 2-phenoxyethanol 3b and 2-(phenylthio)ethanol 3c was studied by surface response methodology. A possible mechanism involving a radical pathway is discussed in terms of bond dissociation energies, thermal stability of the pyrolysis products and configuration of the radical intermediates. Elsevier,.

Model studies of the thymidylate synthase reaction. The mechanism of reduction of 5-uracilylmethylenepyridinium salts by benzyl thiol

The reduction of 5-uracilylmethylenepyridinium salts by benzyl thiols, to the corresponding thymine derivatives, involves an exocyclic methylene intermediate, which appears to be reduced by a radical mechanism. The overall reaction constitutes a mechanist

Reactions of Wittig Reagents with Episulfides or Elemental Sulfur

The reactions of Wittig reagents with episulfides gave symmetrical olefins and triphenylphosphine sulfide in moderate yields.The same olefins were obtained by reactions of Wittig reagents with elementar sulfur.These reactions might proceed through thiocarbonyl intermediates, the existence of which was confirmed by Diels-Alder reactions with dienes.

GENERATION OF THIOALDEHYDES VIA FLUORIDE INDUCED ELIMINATION OF Α-SILYLDISULFIDES

A mild, efficient and general method for the generation of reactive thioaldehydes from α-silyldisulfides is described.

ADDITION REACTIONS OF SOME SIMPLE THIOALDEHYDES.

When generated at 100 deg C, aliphatic and aromatic thioaldehydes without electronic bias are shown to undergo addition reactions to both aliphatic and aromatic 1,3-dienes.The reaction is shown to have application in an intramolecular example.