6736-97-6Relevant articles and documents
Further 2R-Benzylmalate derivatives from the undergrounds parts of Arundina graminifolia (Orchidaceae)
Auberon, Florence,Olatunji, Opeyemi Joshua,Waffo-Teguo, Pierre,Makinde, Emmanuel Ayobami,Forstinus Nwabor, Ozioma,Bonté, Frédéric,Mérillon, Jean-Michel,Lobstein, Annelise
, p. 156 - 163 (2019/12/11)
Nine new glucosyloxybenzyl 2R-benzylmalate derivatives, named arundinosides R–Z (1-9) were isolated from the underground parts of Arundina graminifolia. The structures of the new compounds were elucidated by in-depth spectroscopic data analysis including
Real-time evaluation of binding mechanisms in multivalent interactions: A surface plasmon resonance kinetic approach
Munoz, Eva Maria,Correa, Juan,Riguera, Ricardo,Fernandez-Megia, Eduardo
supporting information, p. 5966 - 5969 (2013/05/22)
Multivalency is a key, ubiquitous phenomenon in nature characterized by a complex combination of binding mechanisms, with special relevance in carbohydrate-lectin recognition. Herein we introduce an original surface plasmon resonance kinetic approach to analyze multivalent interactions that has been validated with dendrimers as monodisperse multivalent analytes binding to lectin clusters. The method, based on the analysis of early association and late dissociation phases of the sensorgrams provides robust information of the glycoconjugate binding efficiency and real-time structural data of the binding events under the complex scenario of the glyco-cluster effect. Notably, it reveals the dynamic nature of the interaction and offers experimental evidence on the contribution of binding mechanisms.
Triterpenoid saponins from Gynostemma pentaphyllum
Shi, Lin,Cao, Jia-Qing,Shi, Sheng-Ming,Zhao, Yu-Qing
experimental part, p. 168 - 177 (2011/03/23)
Four new dammarane-type triterpene saponins, 1-4, were isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino. Their structural elucidations were accomplished mainly on the basis of spectroscopic methods, such as IR, HR-TOF-MS, and NMR. Compounds 1-4 showed moderate cytotoxic activities against cancer cell lines HL-60, Colon205, and Du145 in vitro.