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Benzamide, N-(2-methyl-4-oxo-3(4H)-quinazolinyl)-, also known as 2-methyl-N-phenylquinazolin-4(3H)-one, is a chemical compound with the molecular formula C15H12N2O2. It is a derivative of benzamide, featuring a quinazolinone ring system, which is a heterocyclic aromatic ring structure. Benzamide, N-(2-methyl-4-oxo-3(4H)-quinazolinyl)- is characterized by its white to off-white crystalline appearance and is soluble in organic solvents. It is primarily used in the synthesis of various pharmaceuticals and agrochemicals due to its potential biological activities, such as anti-inflammatory, analgesic, and anti-cancer properties. The compound's structure and properties make it a valuable intermediate in the development of new drugs and chemical compounds.

6761-14-4

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6761-14-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6761-14-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,6 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6761-14:
(6*6)+(5*7)+(4*6)+(3*1)+(2*1)+(1*4)=104
104 % 10 = 4
So 6761-14-4 is a valid CAS Registry Number.

6761-14-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2-methyl-4-oxoquinazolin-3(4H)-yl)benzamide

1.2 Other means of identification

Product number -
Other names 3-benzoylamino-2-methyl-3H-quinazolin-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6761-14-4 SDS

6761-14-4Relevant academic research and scientific papers

An efficient one-pot access to quinazolinone derivatives using TiO 2 nanoparticles as catalyst: Synthesis and vasorelaxant activity evaluation

Khalafi-Nezhad, Ali,Haghighi, Saghar Mowlazadeh,Purkhosrow, Azar,Panahi, Farhad

experimental part, p. 920 - 924 (2012/06/15)

A variety of quinazolinone derivatives were successfully synthesized, via a three-component condensation reaction between anthranilic acid, acetic anhydride, and amines. This process was accomplished in the presence of catalytic amount of titanium dioxide

Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases

Khan, Mahmud Tareq Hassan,Khan, Rasool,Wuxiuer, Yimingjiang,Arfan, Mohammad,Ahmed, Manzoor,Sylte, Ingebrigt

experimental part, p. 4317 - 4327 (2010/09/12)

A combinatorial series of novel quinazolin-4(3H)-ones were synthesised and their structures were established based on spectroscopic data (IR, NMR, EI-MS, and FAB-MS). The compounds were tested for inhibition of the zinc metalloproteinase thermolysin (TLN) utilizing a chemical array-based approach. Some of the compounds were found to inhibit TLN, with IC50 values ranging from 0.0115 μM (compound 3) to 122,637 μM (compound 29). Compound 3 [3-phenyl-2-(trifluoromethyl) quinazolin-4(3H)-one] (IC50 = 0.0115 μM) and compound 35 [3-(isopropylideneamino)-2,2-dimethyl-2,3-dihydroquinazolin-4 (1H)-one] (IC50 = 0.2477 μM) were found to be the most potent inhibitors.

Synthesis ans Biological Evaluation of Some New Fused Quinzoline Derivatives

Ibrahim, S. S.,Abdel-Halim, A. M.,Gabr, Y.,El-Edfawy, S.,Abdel-Rahman, R. M.

, p. 1041 - 1063 (2007/10/03)

Some new fused quinazoline derivatives have been prepared by reacting 3-N-acyl / aroylamino quinazolin-4(3)-ones (2) with different nucleophilic reagents.The structural assignments of all the new products were based on elemental analysis and chemical and spectroscopic data, and somw of the products have been screened for their antimicrobial activity. - Key Words: synthesis; biological; fused quinazolines

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