30909-95-6

Basic information

• Product Name: 2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one
• CAS NO: 30909-95-6
• Molecular Formula: C₁₄H₁₁N₃O
• Molecular Weight: 237.2566
• Mol File: 30909-95-6.mol
• Article Data: 7

Chemical Properties

• Density: 1.29g/cm³
• Refractive Index: 1.679
• CAS DataBase Reference: 2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one(30909-95-6)
• EPA Substance Registry System: 2-phenyl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one(30909-95-6)

Safety Data

• Hazardous Substances Data: 30909-95-6(Hazardous Substances Data)

Upstream product

• 538-51-2 benzylidene phenylamine 
• 1904-58-1 anthranilic acid hydrazide 
• 65-85-0 benzoic acid 
• 707-07-3 orthobenzoic acid trimethyl ester 
• 1663-61-2 triethoxymethylbenzene 
• 28864-27-9 1-(2'-aminobenzoyl)-2-benzoylhydrazine 
• 1022-46-4 2-phenyl-4H-3,1-benzoxazin-4-one 
• 118-48-9 isatoic anhydride 
• 613-94-5 benzoic acid hydrazide 

Downstream Products

• 97625-16-6 2-(2-Acetylaminophenyl)-5-phenyl-1,3,4-oxadiazole 
• 97625-15-5 3-Diacetylamino-2-phenyl-4(3H)-quinazolinone 
• 1904-60-5 3-amino-2-phenylquinazolin-4(3H)-one 
• 23047-95-2 2-(o-aminophenyl)-5-phenyl-1,3,4-oxadiazole 
• 1022-45-3 2-phenyl-4(3H)-quinazolinone 
• 6761-14-4 N-(2-methyl-4-oxoquinazolin-4(3H)-yl)benzamide 
• 6761-16-6 N₃-acetylamino-2-phenyl-4(3H)-quinazolinone 

Relevant articles and documents

Reaction of 2-Aminobenzoylhydrazines with Carboxylic Acids: Formation of Quinazolin-4(3H)-one, 1,3,4-Oxadiazole and 1,3,4-Benzotriazepin-5-one Derivatives

Reactions of 2-aminobenzoylhydrazines with aliphatic acids give 1-(2'-acylaminobenzoyl)-2-acylhydrazines (4) which are cyclised to 3-amino-2-alkylquinazolin-4(3H)-ones (6).Aromatic acids react with 2-aminobenzoylhydrazines to give a mixture of 1-(2'-amino

A New Synthesis of 2-Aryl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones

The reaction of 2-aryl-3,1-benzoxazine-4-ones (1) and hydrazine hydrate in refluxing xylene yields 2-aryl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones in 55-74percent yield.In basic conditions this reaction, however, gives 2-aryl-3-aminoquinazolin-4(3H)-one

The Chemistry of 2-Aminobenzoyl Hydrazides. 1. Effects of Orthoester Substituents on the Mode of Cyclization

Treatment of substituted 2-aminobenzoyl hydrazides with orthoesters has been found to yield different products depending upon the type of orthoester employed.Equimolar quantities of orthoester and hydrazide yield 3-amino-4(3H)-quinazolinones, whereas utilization of a two-fold excess (or greater) of orthoester yields, in some cases, 3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones as minor products in addition to N-imidate esters as major products.Treatment of hydrazides with trimethyl orthobenzoate yields substituted 5-(2-aminophenyl)-1,3,4-oxadiazoles and 3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones.The steric bulk of the phenyl group in trimethyl orthobenzoate effects the formation of adduct at the β-nitrogen of the hydrazide which cyclized to the oxadiazole and benzotriazepinone products.In the aliphatic orthoester series, the formation of adduct to the aromatic amino group appears to be favored which gives rise to quinazolinone and benzotriazepinone products.