684250-09-7

Basic information

• Product Name: 2,4-dichloro-6-ethynyl-aniline
• Synonyms: 2,4-Dichloro-6-ethynylaniline; 2,4-Dichloro-6-ethynyl-phenylamine; benzenamine, 2,4-dichloro-6-ethynyl-
• CAS NO: 684250-09-7
• Molecular Formula: C₈H₅Cl₂N
• Molecular Weight: 186.038
• Mol File: 684250-09-7.mol

Chemical Properties

• Boiling Point: 286.2°C at 760 mmHg
• Flash Point: 126.9°C
• Density: 1.39g/cm³
• Vapor Pressure: 0.00267mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: 2,4-dichloro-6-ethynyl-aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloro-6-ethynyl-aniline(684250-09-7)
• EPA Substance Registry System: 2,4-dichloro-6-ethynyl-aniline(684250-09-7)

Safety Data

• Hazardous Substances Data: 684250-09-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,4-dichloro-6-ethynyl-aniline is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex organic molecules that are vital in medicinal chemistry.
Used in Organic Chemistry:
In the field of organic chemistry, 2,4-dichloro-6-ethynyl-aniline is employed as a reagent, facilitating specific reactions that are crucial for the development of new organic compounds and materials.

Upstream product

• 684250-19-9 2,4-dichloro-6-trimethylsilanylethynylaniline 
• 697-90-5 2,4-dichloro-6-iodoaniline 
• 697-86-9 2,4-dichloro-6-bromoaniline 

Downstream Products

• 1616975-17-7 5,7-dichloro-1-tosylindolin-3-one 
• 1616975-07-5 N-(2,4-dichloro-6-ethynylphenyl)-4-methylbenzenesulfonamide 
• 5326-35-2 5,7-dibromo-2-phenyl-1H-indole 
• 1438414-86-8 5,7-dichloro-3-fluoro-2-phenyl-1H-indole 
• 1438414-81-3 5,7-dichloro-3,3-difluoro-2-phenyl-3H-indole 
• 1438414-73-3 2,4-dichloro-6-(2-phenylethynyl)benzeneamine 
• 684250-13-3 5,7-dichloro-2-(4-methoxyphenyl)-1H-indole 
• 4792-72-7 5,7-dichloro-1H-indole 
• 684250-05-3 2,4-dichloro-6-(3,4-dihydronaphthalen-1-ylethynyl)phenylamine 
• 684250-07-5 2,4-dichloro-6-[(4-methoxyphenyl)ethynyl]aniline 

Relevant articles and documents

Flexible and practical synthesis of 3-oxyindoles through gold-catalyzed intermolecular oxidation of o-ethynylanilines

A novel gold-catalyzed intermolecular oxidation of o-ethynylanilines has been developed. A range of functionalized 3-oxyindoles are readily accessed by utilizing this strategy. Importantly, this gold-catalyzed oxidative process outcompetes the typical ind

Gold(III)-catalyzed annulation of 2-alkynylanilines: A mild and efficient synthesis of indoles and 3-haloindoles

Gold(III)-catalyzed annulation of 2-alkynylanilines in EtOH or EtOH-water mixtures at room temperature gives indoles derivatives in good yields. One-flask protocol for the gold-catalyzed conversion of 2-alkynylanilines to 3-bromo and 3-iodoindoles is also reported.