68494-08-6

Usage

Uses

Used in Pharmaceutical and Medicinal Applications:
4,5-BIS(BENZOYLTHIO)-1,3-DITHIOLE-2-THIONE is used as a therapeutic agent for its antioxidative and anti-inflammatory properties, which contribute to the treatment of various conditions such as cancer, diabetes, and cardiovascular diseases.
Used in Cancer Treatment:
In the field of oncology, 4,5-BIS(BENZOYLTHIO)-1,3-DITHIOLE-2-THIONE is used as a potential anticancer agent, with studies indicating its effectiveness in managing cancerous conditions.
Used in Diabetes Management:
4,5-BIS(BENZOYLTHIO)-1,3-DITHIOLE-2-THIONE is utilized as a component in diabetes treatments, leveraging its properties to help manage and alleviate symptoms associated with the disease.
Used in Cardiovascular Disease Treatment:
Within the cardiovascular industry, 4,5-BIS(BENZOYLTHIO)-1,3-DITHIOLE-2-THIONE is applied as a therapeutic intervention to combat the effects of cardiovascular diseases, capitalizing on its antioxidative nature.
Used in Gene Expression and Cellular Response Modulation:
4,5-BIS(BENZOYLTHIO)-1,3-DITHIOLE-2-THIONE is also used in research and development for its ability to modulate gene expression and cellular responses, suggesting a broad range of potential therapeutic benefits across various diseases and conditions.

Upstream product

• 75-15-0 carbon disulfide 
• 98-88-4 benzoyl chloride 
• 74-88-4 methyl iodide 
• 72022-68-5 bis(tetraethylammonium)bis(2-thioxo-1,3-dithiole-4,5-dithiolate)zincate 
• 2819-08-1 benzoyl acetate 

Downstream Products

• 70800-59-8 1,3,4,6-tetrathiapentalene-2-thione 
• 136414-44-3 10aH-1,3,4,5-Tetrathia-cyclohepta[e]indene-2-thione 
• 65-85-0 benzoic acid 
• 136414-45-4 6-Phenyl-10aH-1,3,4,5-tetrathia-cyclohepta[e]indene-2-thione 
• 136414-46-5 6-(4-Methoxy-phenyl)-10aH-1,3,4,5-tetrathia-cyclohepta[e]indene-2-thione 
• 68494-09-7 4,5-bis(benzoylthio)-1,3-dithiole-2-one 
• 88203-73-0 Tetrakis(benzoylthio)-tetrathiofulvalen 
• 59065-21-3 4,5-bis(2-ethylsulfanyl)-1,3-dithiole-2-thione 
• 138206-22-1 4,5-Bis-(2,4-dinitro-phenylsulfanyl)-[1,3]dithiole-2-thione 
• 111082-47-4 4,5-(phenyl-ethylenedithio)-1,3-dithiole-2-thione 
• 117408-73-8 Benzo<1,2-g;4,5-g'>bis<1,3>dithiolo<4,5-b><1,4>dithiocine-2,10-dithione 
• 96133-64-1 4,5-bis(p-methoxybenzylthio)-1,3-dithiole-2-thione 
• 96133-61-8 4,5-Bis(2-nitrobenzylthio)-1,3-dithiol-2-thion 
• 145839-48-1 6-{2-[2-(2-{2-[4-(2-{2-[2-(4-Trityl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-6,7-dihydro-5H-[1,3]dithiolo[4,5-b][1,4]dithiepine-2-thione 

Relevant academic research and scientific papers

Vibration assignment of carbon-sulfur bond in 2-thione-1,3-dithiole-4,5-dithiolate derivatives

The higher frequency peak near 1050 cm-1 of the doublet in the infrared and Raman spectra of 2-thione-1,3-dithiole-4,5-dithiolate (DMIT) derivatives corresponds mainly to the stretching vibration of carbon-sulfur double bond in the terminal S=C

Selective Metalations of 1,4-Dithiins and Condensed Analogues Using TMP-Magnesium and -Zinc Bases

TMPMgCl·LiCl and TMPZnCl·LiCl allow facile magnesiation and zincation, respectively, of the 1,4-dithiin scaffold, producing polyfunctionalized 1,4-dithiins. A subsequent metalation of these S-heterocycles can also be achieved with the same TMP bases, lead

The synthesis of anthracene, and dipyridine salts as cations for DMIT complexes

The synthesis of a series of cations for the preparation of [Ni(dmit) 2]2 complexes is described. These cations are a series of 9,10-disubstituted anthracene derivatives with phosphane or alkylamine sustituents. Metal catalysed coupling reactions were used to prepare the 9,10-ethynylanthracene derivatives, one of which was subsequently methylated, using iodomethane as methylating reagent, to form cations for [Ni(dmit) 2]2-salts. A range of salts were prepared using ferrocene and anthracene-based cations with [Ni(dmit)2]2- as the dianion.

One-step synthesis of carbon-sulphur heterocyclic ring by electrochemical reduction of carbon disulphide at platinum electrode

The electro reductive cyclization of carbon disulphide in nonaqueous solvent is reported here. At constant potential, the electrolysis of carbon disulphide was carried out in the presence of an electrophile i.e. alkyl cation, acyl cation etc. using N/N-di

Biscrown-annulated TTFAQ-dianthracene hybrid: Synthesis, structure, and metal ion sensing

A new fluorescence chemosensor (3) made up of a biscrown-annulated TTFAQ receptor and two anthracene fluorophores was designed and synthesized. Its solid-state structure was disclosed by X-ray crystallographic analysis, while fluorescence titrations indic

Synthesis of pyrazinoporphyrazine derivatives functionalised with tetrathiafulvalene (TTF) units: X-ray crystal structures of two related TTF cyclophanes and two bis(1,3-dithiole-2-thione) intermediates

The pyrazinoporphyrazine system 13 (metal-free, zinc and copper derivatives) has been synthesised by tetramerisation of 2,3-dicyanopyrazine monomer unit 10. The structure of 13a-c has been established by HNMR spectroscopy, UV/Vis spectrophotometry, MALDI-TOF mass spectrometry, cyclic voltammetry and differential pulse voltammetry. The electrochemical redox behaviour of 13a-c is strongly solvent dependent. The expected two-stage oxidation of the tetrathiafulvalene (TTF) units of 13a-c was observed in a range of solvents; in addition, oxidation and reduction of the pyrazinoporphyrazine core of the metal-free derivative 13a was detected in benzonitrile. On excitation of 13 in the Q-band region no fluorescence was observed, which is presumably the consequence of intramolecular charge transfer between the TTF moieties and the excited state of the central porphyrazine. Molecular modelling studies on 13a and 13c are reported. During the course of this work, the novel TTF macrocycles 11 and 20 were synthesised; their X-ray crystal structures reveal severely bent TTF units, the conformations of which are discussed in detail. The X-ray crystal structures of the bis(1,3-dithiole) systems 15 and 18 have also been determined.

THE STUDY OF CHARGE TRANSFER COMPLEXES OF BEDT-TTF DERIVATIVES

We have synthesized BEDT-TTF derivatives, which include eight sulfur atoms per molecule, and prepared several charge transfer (CT) complexes with TCNQs, p-quinones, and TCNEs in order to clarify the steric effect of substituents, R.Some of the CT complexes revealed high conductivities.