6970-28-1

Usage

Uses

Used in Pharmaceutical Applications:
(R)-2,4-Diaminobutyric acid dihydrochloride is used as a therapeutic agent for conditions such as epilepsy and neurodegenerative diseases. Its application is based on its potential to alleviate symptoms and improve the quality of life for patients suffering from these conditions.
Used in Research Applications:
In research, (R)-2,4-Diaminobutyric acid dihydrochloride is used as a chemical probe to study the function of neurotransmitter receptors in the brain. Its application is due to its unique chemical structure and biological activity, which allows for the investigation of receptor interactions and potential enhancements in receptor function.
Used in Aqueous Solutions and Biological Systems:
The dihydrochloride salt form of (R)-2,4-Diaminobutyric acid is used as a soluble compound in aqueous solutions and biological systems. Its application is based on its water solubility, which makes it suitable for a wide range of experiments and therapeutic uses in various medical and research contexts.

InChI:InChI=1/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8)/t3-/m1/s1

Upstream product

• 103668-08-2 (R)-2,4-Diamino-butyric acid ethyl ester; hydrochloride 
• 34404-27-8 N^α,N^γ-bis(t-butoxycarbonyl)-L-α,γ-butyric acid 
• 127531-09-3 (S)-3-Cyano-2-[(1R,2R,5R)-2-hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-propionic acid ethyl ester 

Downstream Products

• 2483-65-0 3-amino-pyrrolidin-2-one 
• 117106-22-6 (S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-aminobutanoic acid 
• 126581-98-4 DPAB-L-DBA (trans) 
• 1217645-10-7 (R)-2,4-bis((((9H-fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid 
• 55478-23-4 (S)-2,4-bis(((benzyloxy)carbonyl)amino)butanoic acid 
• 4128-00-1 (3S)-3-aminopyrrolidin-2-one 
• 25139-87-1 ⁽⁵⁾-(+)(D)-N,N'-Ditosyl-2,4-diamino-butanol 
• 97347-23-4 N^α,N^γ-diBoc-L-2,4-diaminobutyric acid p-nitrobenzyl ester 

Relevant academic research and scientific papers

Preparation of enantiopure 2-acylazetidines and their reactions with chloroformates

Enantiopure 1-phenylethylazetidine-2-carboxylates and 2-acylazetidines were prepared and reacted with chloroformates to yield α-chloro-γ-amino butyric acid esters and ketones from ring opening reaction of azetidinium ion intermediate in a completely regio- and stereoselective manner.

ENANTIOSELECTIVE SYNTHESIS OF OPTICALLY PURE NATURAL S(+) OR UNNATURAL R(-) DABA

After optimization of the reaction conditions, optically pure S(+) DABA is obtained in more than 80percent overall yield.A modell is proposed to explain the dependence of asymmetric induction on the nature of the counter ion (Li(1+), Mg(2+), Bu4N(1+)).