69843-08-9

Basic information

• Product Name: Benzene, 1-methoxy-4-[1-(trifluoromethyl)ethenyl]-
• CAS NO: 69843-08-9
• Molecular Formula: C10H9F3O
• Molecular Weight: 202.176
• Mol File: 69843-08-9.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-4-[1-(trifluoromethyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-4-[1-(trifluoromethyl)ethenyl]-(69843-08-9)
• EPA Substance Registry System: Benzene, 1-methoxy-4-[1-(trifluoromethyl)ethenyl]-(69843-08-9)

Safety Data

• Hazardous Substances Data: 69843-08-9(Hazardous Substances Data)

Upstream product

• 76953-96-3 1-(4-methoxyphenyl)-1-(trifluoromethyl)ethanol 
• 1514-82-5 2-bromo-3,3,3-trifluoropropene 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 637036-90-9 (±)-trimethyl({[1,1,1-trifluoro-2-(4-methoxyphenyl)propan-2-yl]oxy})silane 
• 69843-10-3 1-chloro-4-(1,1,1-trifluoroprop-2-en-2-yl)benzene 
• 536-74-3 phenylacetylene 
• 696-62-8 para-iodoanisole 
• 711-38-6 4'-methoxy-2,2,2-trifluoroacetophenone 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 5720-07-0 4-methoxyphenylboronic acid 
• 2730-62-3 2-chloro-1,1,1-trifluoropropene 
• 124-63-0 methanesulfonyl chloride 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 76953-96-3 1-(4-methoxyphenyl)-1-(trifluoromethyl)ethanol 
• 1079398-12-1 1-(1,1-difluoro-3-phenylprop-1-en-2-yl)-4-methoxybenzene 
• 1541177-63-2 3,3,3-trifluoro-2-(4-methoxyphenyl)propane-1,2-diol 
• 1541177-61-0 1-(1-bromo-3,3,3-trifluoroprop-1-en-2-yl)-4-methoxybenzene 
• 1541177-64-3 1-(1-bromo-3,3,3-trifluoroprop-1-en-2-yl)-4-methoxybenzene 
• 1431983-72-0 1-(2,2-difluoro-1-(trifluoromethyl)cyclopropyl)-4-methoxybenzene 
• 1541177-62-1 1-(3,3-difluoro-2-(4-methoxyphenyl)allyl)piperidine 
• 1638968-66-7 (3-fluoro-4-(4-methoxyphenyl)cyclopenta-1,3-diene-1,2-diyl)dibenzene 

Relevant articles and documents

Electroreductive Cross-Coupling of Trifluoromethyl Alkenes and Redox Active Esters for the Synthesis of Gem-Difluoroalkenes

An electroreductive access to gem-difluoroalkenes has been developed through the decarboxylative/defluorinative coupling of N-hydroxyphtalimides esters and α-trifluoromethyl alkenes. The electrolysis is performed under very simple reaction conditions in a

Remote Regioselective Radical C-H Functionalization of Unactivated C-H Bonds in Amides: The Synthesis of gem-Difluoroalkenes

The site-selective functionalization of unactivated aliphatic amines is an attractive and challenging synthetic approach. We herein report a general strategy for the remote site-selective functionalization of unactivated C(sp3)-H bonds in amides by photogenerated amidyl radicals to form gem-difluoroalkenes with trifluoromethyl-substituted alkenes. The site selectivity is controlled by a 1,5-hydrogen atom transfer (HAT) process of the amide. This photocatalyzed transformation shows both chemo- and site-selectivity, facilitating the formation of a secondary, tertiary, or quaternary carbon center.

Photoredox relay-catalyzedgem-difluoroallylation of alkyl iodides

Herein, a new example of relay catalysis, using a combination of Mn2(CO)10and an iridium-based photocatalyst, is reported. In our relay catalytic reaction, the Mn catalyst and iridium-based photocatalyst catalyze the reaction at different stages in the desired sequence under the same reaction conditions, and do not inhibit each other. This convenient method transforms a broad scope of alkyl iodides into the correspondinggem-difluoroalkenesviaC(sp3)-C(sp3) bond construction. The protocol has good functional group tolerance and is suitable for the late-stage modification of multifunctional complex molecules.