7031-95-0

Upstream product

• 98-88-4 benzoyl chloride 
• 2564-83-2 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical 
• 100-52-7 benzaldehyde 
• 67-56-1 methanol 
• 613-94-5 benzoic acid hydrazide 
• 140-29-4 phenylacetonitrile 
• 121-69-7 N,N-dimethyl-aniline 
• 106-49-0 p-toluidine 
• 611-73-4 Benzoylformic acid 
• 119-65-3 isoquinoline 
• 108-88-3 toluene 
• 3102-33-8 trans-3-penten-2-one 
• 67-64-1 acetone 
• 109-04-6 2-bromo-pyridine 

Downstream Products

• 1380288-24-3 2,2,6,6-tetramethyl-1-(o-tolyl)piperidine 
• 1380288-23-2 2,2,6,6-tetramethyl-1-(4-nitrophenyl)piperidine 
• 1372405-00-9 2,2,6,6-tetramethyl-1-(4-phenylbutyl)piperidine 

Relevant academic research and scientific papers

Oxidative Annulation of 3-Aryl-2H-benzo[e][1,2,4]thiadiazine-1,1-dioxides with Aryl Aldehydes: An Easy Access to Hydroxyisoindolo[1,2-b] benzothiadiazinedioxide Scaffolds

A novel and efficient approach has been developed for the synthesis of a diverse range of hydroxyisoindolo[1,2-b]benzothiadiazinedioxide derivatives through a sequential palladium catalyzed cross-dehydrogenative coupling (CDC) and intramolecular cyclizati

Metal-Free Oxidative Decarboxylative Acylation/Ring Expansion of Vinylcyclobutanols with α-Keto Acids by Visible Light Photoredox Catalysis

A metal-free visible-light-mediated decarboxylative acylation/ring expansion of vinylcyclobutanols with α-keto acids has been developed. Hypervalent iodine reagent was found to be important for promoting decarboxylation of α-keto acids in this tandem radical process. This protocol has been successfully applied to synthesis of a variety of substituted 1,4-dicarbonyl compounds and tolerated some functional groups well.

S-(Diethyl phosphonodifluoromethyl)Benzenesulfonothioate: A New Reagent for the Synthesis of SCF2PO(OEt)2-containing Molecules

In this manuscript, the synthesis of an original SCF2PO(OEt)2-containing reagent was depicted. Thanks to the unique properties of this newly-designed source, an unprecedented transformation with aldehydes was conducted under radical

Aroylchlorination of 1,6-Dienes via a Photoredox Catalytic Atom-Transfer Radical Cyclization Process

A method using aroyl chlorides as atom-transfer radical cyclization agents in a novel visible-light photocatalytic aroylchlorination reaction is developed. The overall transformation involves the formation of two new C-C bonds and one new C-Cl bond in a o

The regioselective coupling of 2-arylquinazolinone C-H with aldehydes and benzyl alcohols under oxidative conditions

The direct and regioselective palladium-catalyzed dehydrogenative coupling of aldehydes and benzyl alcohols with 2-aryl-quinazolinone C-H endowed with a quinazolinone nucleus, which is one of the most fascinating and vital core units, as an inherent directing group under oxidative conditions was developed. This atom/step economic aroylation offers an attractive handle and a very green approach for highly convergent and diversity-oriented synthetic modifications and the construction of vital molecules of therapeutic interest. This journal is

Decarboxylative cascade cyclization of α-keto acids with 2-cyano-3-arylaniline-derived acrylamides

An oxidative decarboxylative cascade cyclization of α-keto acids with 2-cyano-3-arylaniline-derived acrylamides was developed. This cascade reaction exhibits a broad substrate scope, and provides an efficient access to carbonyl-containing pyrido[4,3,2-gh]

Palladium-catalyzed late-stage mono-aroylation of the fully substituted pyrazoles via aromatic C–H bond activation

The palladium-catalyzed late-stage aroylation of 4-methyl-1,5-diaryl-1H-pyrazole-3-carboxylates has been developed via direct and exclusive mono-Csp2–H bond activation with broad substrate scope and good functional group tolerance. A dual-core

Diastereoselective Synthesis of Oxazoloisoindolinones via Cascade Pd-Catalyzed ortho-Acylation of N-Benzoyl α-Amino Acid Derivatives and Subsequent Double Intramolecular Cyclizations

The first cascade diastereoselective synthesis of oxazoloisoindolinones via the palladium-catalyzed decarboxylative ortho-acylation of N-benzoyl α-amino acid derivatives followed by double intramolecular cyclizations has been demonstrated. This reaction, using α-amino acids as directing groups and α-oxocarboxylic acids as the acylation source, features a broad substrate scope, good functional group tolerance, high regioselectivity, and excellent diastereoselectivity.

Synthesis of Fused Pyran Derivatives via Visible-Light-Induced Cascade Cyclization of 1,7-Enynes with Acyl Chlorides

A photocatalytic cascade cyclization of 1,7-enynes with acyl chlorides has been established. This method offers an operationally simple access to diverse fused pyran derivatives with a broad substrate scope in high yields from simple acyl chlorides via an acyl radical intermediate.

Iron-Catalyzed Divergent Tandem Radical Annulation of Aldehydes with Olefins toward Indolines and Dihydropyrans

Iron-catalyzed divergent tandem radical annulations of aldehydes with olefins are reported. The new strategy allows the rapid and efficient construction of various multifunctionlized indolines (R = Ar) and dihydropyrans (R = Me), which are significant skeletons in bioactive natural products and pharmaceuticals. The substituents of tertiary amines play vital roles to facilitate the desired transformation. Mechanistic studies on indoline formation disclose that the homolytic cleavage of the carbonyl C-H bond might be involved in the rate-determining step, while dissociation of the aromatic C-H bond was most likely included in the product-determining step.