70326-37-3

Basic information

• Product Name: 3-Benzoylthiazolidine-2-thione
• Synonyms: 3-Benzoylthiazolidine-2-thione;3-Benzoyl-2-thiazolidinethione;N-Benzoylthiazolidine-2-thione;Phenyl(2-thioxo-3-thiazolidinyl)methanone;3-benzoyl-1,3-thiazolidine-2-thione;MFCD00457448;phenyl-(2-sulfanylidene-1,3-thiazolidin-3-yl)methanone;Phenyl-(2-thioxo-thiazolidin-3-yl)-methanone
• CAS NO: 70326-37-3
• Molecular Formula: C₁₀H₉NOS₂
• Molecular Weight: 223.31456
• Product Categories: chemical additive;pharmaceutical intermediate
• Mol File: 70326-37-3.mol
• Article Data: 11

Chemical Properties

• Melting Point: 113-114℃
• Boiling Point: 349.9±25.0 °C(Predicted)
• Appearance: /
• Density: 1.39
• PKA: -2.49±0.20(Predicted)
• CAS DataBase Reference: 3-Benzoylthiazolidine-2-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzoylthiazolidine-2-thione(70326-37-3)
• EPA Substance Registry System: 3-Benzoylthiazolidine-2-thione(70326-37-3)

Safety Data

• Hazardous Substances Data: 70326-37-3(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 70326-37-3 differently. You can refer to the following data:
1. thiazolidin e thione pharmaceutical intermediate
2. 3-Benzoylthiazolidine-2-thione is a useful reactant for the synthesis of organic compounds such as 2-?(1-?acylazetidin-?3-?yl)?thio-?1,?3-?thiazolines, and E)?-?1-?Hydroxy-?2-?methyl-?but-?2-?enyl 4-?diphosphate.

Upstream product

• 134469-06-0 thiazolidine-2-thione 
• 93-97-0 benzoic acid anhydride 
• 96-53-7 2-mercaptothiazoline 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 63987-96-2 thallium salt of Δ²-1,3-thiazoline-2-thiol 

Downstream Products

• 6789-88-4 hexyl benzoate 
• 744-59-2 N-benzoylglycyl-L-phenylalanine 
• 14281-55-1 PhCO-Gly-PheOMe 
• 80681-03-4 N-[2-Oxo-2-(2-thioxo-thiazolidin-3-yl)-ethyl]-benzamide 
• 1181808-95-6 2-(1-benzoylazetidin-3-yl)thio-1,3-thiazoline 
• 1009734-71-7 N-[({[(2E)-4-(tert-butyl(diphenyl)silyloxy)-3-methylbut-2-en-1-yl]oxy}amino)sulfonyl]benzamide 
• 79251-84-6 N^ε-benzoyl-L-lysine methyl ester hydrochloride 
• 79251-83-5 N-acyl-N^ε-benzoyl-L-lysine methyl ester 
• 100-51-6 benzyl alcohol 
• 100-52-7 benzaldehyde 
• 1485-70-7 N-benzylbenzamide 
• 495-69-2 Hippuric Acid 
• 2782-40-3 N-butylbenzamide 
• 5894-65-5 N-t-butylbenzamide 

Relevant articles and documents

Exploring hydrogen peroxide responsive thiazolidinone-based prodrugs

A novel approach for developing prodrugs based on masked carboxylic acids is described. Rather than using conventional esterase-based activation, thiazolidinone protecting groups have been identified that can reveal carboxylic acid groups upon activation by hydrogen peroxide. This may prove valuable in the continuing development of prodrug strategies that rely on reactive oxygen species (ROS) as a trigger. This journal is

NOVEL VINBLASTINE DERIVATIVES, THEIR PREPARATION, USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAID DERIVATIVES

The invention provides vinblastine derivatives represented by the following formula 1 or their physiologically acceptable salts, their preparation, use and pharmaceutical compositions comprising the said derivatives. The said vinblastine derivatives show inhibiting activities against tumor cell lines and can be used as medicaments for treating malignant tumors.

2-Chloro-1,3-dimethylimidazolinium chloride. 1. A powerful dehydrating equivalent to DCC

2-Chloro-1,3-dimethylimidazolinium chloride (DMC) (3) can act as a powerful dehydrating agent, replacing DCC (1) under nearly neutral conditions. Its application to acylation and dehydration is described.