7081-78-9

Basic information

• Product Name: 1-chloro-1-ethoxyethane
• Synonyms: 1-chloro-1-ethoxyethane
• CAS NO: 7081-78-9
• Molecular Formula: C₄H₉ClO
• Molecular Weight: 108.56666
• EINECS: 230-378-4
• Mol File: 7081-78-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 122.94°C (rough estimate)
• Flash Point: 21.4°C
• Appearance: /
• Density: 0.9655
• Vapor Pressure: 56.1mmHg at 25°C
• Refractive Index: 1.4053
• CAS DataBase Reference: 1-chloro-1-ethoxyethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-1-ethoxyethane(7081-78-9)
• EPA Substance Registry System: 1-chloro-1-ethoxyethane(7081-78-9)

Safety Data

• Hazardous Substances Data: 7081-78-9(Hazardous Substances Data)

Usage

General Description

1-Chloro-1-ethoxyethane, also known as ethyl chloro(hydroxy)acetal, is a chemical compound with the molecular formula C4H9ClO. It is a colorless liquid with a slightly sweet odor, and is commonly used as an industrial solvent and in organic synthesis. It is a chloroethoxy compound, meaning it contains both a chlorine and an ethoxy group. It is commonly used in the production of pharmaceuticals and other organic compounds. The compound is flammable and may release toxic fumes when heated, so proper safety precautions should be taken when handling and storing it. Additionally, it is important to follow all guidelines and regulations regarding its use and disposal to minimize any potential environmental impact.

InChI:InChI=1/C4H9ClO/c1-3-6-4(2)5/h4H,3H2,1-2H3

Upstream product

• 105-57-7 diethyl acetal 
• 64-17-5 ethanol 
• 6986-48-7 bis-1-chloroethyl ether 
• 10471-14-4 acetaldehyde ethyl methyl acetal 
• 75-07-0 acetaldehyde 
• 109-92-2 ethyl vinyl ether 
• 123-63-7 paracetaldehyde 
• 119072-55-8 tert-butylisonitrile 
• 7647-01-0 hydrogenchloride 
• 10026-13-8 phosphorus pentachloride 
• 98-88-4 benzoyl chloride 
• 60-29-7 diethyl ether 

Downstream Products

• 105-57-7 diethyl acetal 
• 75-00-3 chloroethane 
• 75-07-0 acetaldehyde 
• 20680-10-8 1-(1-ethoxyethoxy)-propane 
• 2679-87-0 butan-2-yl ethyl ester 
• 10471-14-4 acetaldehyde ethyl methyl acetal 
• 1608-72-6 1-ethoxyethyl acetate 
• 623-46-1 1,2-dichloro-2-ethoxyethane 
• 2983-26-8 1,2-dibromoethyl ethyl ether 
• 106-99-0 buta-1,3-diene 
• 109-92-2 ethyl vinyl ether 
• 69843-69-2 2-Benzoyl-3-aethoxybutan 
• 69843-70-5 2-(1-Ethoxyethyl)-4-methylcyclohexanon 
• 51090-48-3 (1-Ethoxyethyl)-phenyl-phosphinsaeureethylester 

Relevant articles and documents

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Simple, rapid procedure for the synthesis of chloromethyl methyl ether and other chloro alkyl ethers

Zinc(II) salts catalyze the reaction between acetals and acid halides to provide haloalkyl ethers in near-quantitative yield. Reactions from millimole to mole scale are typically complete in 1-4 h with 0.01 mol % catalyst. The solutions of haloalkyl ethers thus obtained can be utilized directly in reactions in which the presence of the ester byproduct does not interfere. Excess haloalkyl ether is destroyed on workup, thereby minimizing exposure to this class of carcinogenic compounds.

Electrophilic Reactions of Carbonyl Compounds and Their Derivatives. IX. Reactions of 3,4-Dimethoxyphenylacetone with Heterocarbenium Ions To Form 2-Benzopyrylium Salts

Reactions of 3,4-dimethoxyphenylacetone with a series of carbonyl compounds and their derivatives (benzaldehyde, α-chloroesters, vinyl ethyl ether, and geminal chlorohydrocarbons) as sources of heterocarbenium ions under conditions of acid catalysis and also with heterocarbenium salts yield 2-benzopyrylium salts.