7196-80-7Relevant academic research and scientific papers
Synthesis and structure of 1-ethyl-2,4,5-triphenyl-1H-imidazole (Ethyl-Lophine)
Peppel, Tim,Koeckerling, Martin
, p. 245 - 249 (2013)
Ethyl-Lophine, 1-ethyl-2,4,5-triphenyl-1H-imidazole, C23H 20N2, was synthesized as a precursor for large organic cations in ionic liquids using an improved microwave-assisted method. The title compound and a precursor compound were characterized by NMR, IR, and DSC thermal measurements, as well as elemental analyses. The crystal structure of ethyl-lophine was determined by singlecrystal X-ray structure analysis (triclinic, P1, a = 10:1137(3), b = 12:4935(4), c = 14:6351(4) A, α = 98:182(2), β = 90:694(2), γ = 102:666(2), Z = 4, wR2 = 0:1030 for 611 refined parameters).
Ag–TiO2 nanocomposite-catalyzed one-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles: a green and benign approach
Alipour, Soghra,Vahdat, Seyed Mohammad,Chekin, Fereshteh
, p. 2315 - 2321 (2021/05/27)
Ag–TiO2 nanocomposite as an efficient catalyst was synthesized and characterized by AFM analysis. This nanocomposite acts as a heterogeneous and recyclable catalyst for the room temperature synthesis of 1,2,4,5-tetrasubstituted imidazoles from aldehydes, benzil, ammonium acetate and several anilines or aliphatic amines via one-pot four-component condensation reaction in H2O as a green solvent. Ag–TiO2 nanocomposite was simply recovered by filtration and was reused up to three times.
Tri(1-butyl-3-methylimidazolium) gadolinium hexachloride, ([bmim]3[GdCl6]), a magnetic ionic liquid as a green salt and reusable catalyst for the synthesis of tetrasubstituted imidazoles
Akbari, Ali
supporting information, p. 431 - 434 (2016/01/12)
The magnetic ionic liquid, tri(1-butyl-3-methylimidazolium) gadolinium hexachloride, ([bmim]3[GdCl6]), has been used as an efficient green catalyst for the one-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles via the condensation of benzil, an aromatic aldehyde, aniline, and ammonium acetate. Good to excellent yield, mild reaction conditions, as well as ease of operation and work-up are some advantages of the protocol.
Efficient multi-component synthesis of highly substituted imidazoles utilizing P2O5/SiO2 as a reusable catalyst
Shaterian, Hamid Reza,Ranjbar, Mohammad,Azizi, Kobra
experimental part, p. 1635 - 1645 (2012/01/06)
Phosphorus pentoxide supported on silica gel (P2O 5/SiO2) has been used as an efficient and reusable catalyst for the one-pot pseudo four-component synthesis of 2,4,5-trisubstituted imidazoles from benzil or benzoin, aldehydes, and ammonium acetate. It was also used for four-component preparation of 1,2,4,5-tetrasubstituted imidazoles from benzil or benzoin, aldehydes, primary amine, and ammonium acetate under thermal solvent-free conditions. The remarkable features of this new procedure are high conversions, cleaner reaction, simple experimental and work-up procedures and also the catalyst can be easily separated from the reaction mixture and reused several times without any loss of its activity.
Synthesis of highly substituted imidazoles using Bronsted acidic ionic liquid, triphenyl(propyl-3-sulphonyl)phosphonium toluenesulfonate, as reusable catalyst
Shaterian,Ranjbar,Azizi
experimental part, p. 1120 - 1134 (2012/02/04)
Bronsted acidic ionic liquid, triphenyl(propyl-3-sulphonyl) phosphonium toluenesulfonate, has been used as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions in excellent yields.
SbCl5.SiO2: An efficient alternative for one-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles in solvent or under solvent-free condition
Sadeghi,Mirjalili,Bidaki,Ghasemkhani
experimental part, p. 648 - 652 (2012/07/14)
In a one-pot four-component reaction, an aldehyde, an amine, benzil and ammonium acetate were condensed for the synthesis of 1,2,4,5-tetrasubstituted imidazoles in the presence of silica supported antimony pentachloride (SbCl 5.SiO2) in improved yields. The catalyst is recoverable by simple filtration and can be used in the subsequent reactions.
An environmental friendly approach for the synthesis of highly substituted imidazoles using Br?nsted acidic ionic liquid, N-methyl-2-pyrrolidonium hydrogen sulfate, as reusable catalyst
Shaterian, Hamid Reza,Ranjbar, Mohammad
experimental part, p. 40 - 49 (2012/03/09)
Br?nsted acidic ionic liquid, N-methyl-2-pyrrolidonium hydrogen sulfate, has been used as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles under thermal solvent-free conditions in excellent yields.
A facile multicomponent synthesis of tetrasubstituted imidazoles using Fe3+-K10 catalyst under solvent-free microwave conditions
Raghuvanshi,Singh, Krishna Nand
experimental part, p. 1394 - 1397 (2011/01/13)
An efficient, microwave assisted, multi-component synthesis of 1,2,4,5-tetrasubstituted imidazoles has been achieved by the one-pot condensation of benzil, aromatic aldehyde, aliphatic/aromatic amine and ammonium acetate using Fe3+-K10 heterogeneous catalyst under solvent-free conditions. This approach offers a number of advantages such as excellent yield, solvent-free conditions, short reaction time, an eco-friendly and low loading catalyst, mild reaction temperature, and an easy work-up.
BF3·SiO2: an efficient reagent system for the one-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles
Sadeghi, Bahareh,Mirjalili, Bi Bi Fatemeh,Hashemi, Mohammad M.
, p. 2575 - 2577 (2008/09/21)
Silica-supported boron trifluoride (BF3·SiO2) is an efficient, readily available and reusable catalyst for the synthesis of 1,2,4,5-tetrasubstituted imidazoles using benzil, an aromatic aldehyde and an amine in the presence of ammonium acetate. This one-pot procedure is very simple, affording good to excellent yields.
