7196-80-7

Basic information

• Product Name: 1H-Imidazole, 1-ethyl-2,4,5-triphenyl-
• CAS NO: 7196-80-7
• Molecular Formula: C23H20N2
• Molecular Weight: 324.425
• Mol File: 7196-80-7.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 1-ethyl-2,4,5-triphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 1-ethyl-2,4,5-triphenyl-(7196-80-7)
• EPA Substance Registry System: 1H-Imidazole, 1-ethyl-2,4,5-triphenyl-(7196-80-7)

Safety Data

• Hazardous Substances Data: 7196-80-7(Hazardous Substances Data)

Usage

Structure

Five-membered aromatic heterocycle with two nitrogen atoms at positions 1 and 3, with an ethyl group at position 1 and three phenyl groups at positions 2, 4, and 5.

Type

Derivative of imidazole

Applications

Used as a building block in organic chemistry for the synthesis of other organic compounds, and may have potential pharmaceutical or biological uses.

Upstream product

• 484-47-9 lophine 
• 1627-73-2 1-benzylidene thiosemicarbazide 
• 917-58-8 potassium ethoxide 
• 74-96-4 ethyl bromide 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 100-52-7 benzaldehyde 
• 75-04-7 ethylamine 
• 134-81-6 benzil 
• 6942-03-6 α-benzamidylbenzyl phenyl ketone 

Downstream Products

• 7664-41-7 ammonia 
• 75-04-7 ethylamine 
• 65-85-0 benzoic acid 

Relevant articles and documents

Synthesis and structure of 1-ethyl-2,4,5-triphenyl-1H-imidazole (Ethyl-Lophine)

Ethyl-Lophine, 1-ethyl-2,4,5-triphenyl-1H-imidazole, C23H 20N2, was synthesized as a precursor for large organic cations in ionic liquids using an improved microwave-assisted method. The title compound and a precursor compound were characterized by NMR, IR, and DSC thermal measurements, as well as elemental analyses. The crystal structure of ethyl-lophine was determined by singlecrystal X-ray structure analysis (triclinic, P1, a = 10:1137(3), b = 12:4935(4), c = 14:6351(4) A, α = 98:182(2), β = 90:694(2), γ = 102:666(2), Z = 4, wR2 = 0:1030 for 611 refined parameters).

Tri(1-butyl-3-methylimidazolium) gadolinium hexachloride, ([bmim]3[GdCl6]), a magnetic ionic liquid as a green salt and reusable catalyst for the synthesis of tetrasubstituted imidazoles

The magnetic ionic liquid, tri(1-butyl-3-methylimidazolium) gadolinium hexachloride, ([bmim]3[GdCl6]), has been used as an efficient green catalyst for the one-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles via the condensation of benzil, an aromatic aldehyde, aniline, and ammonium acetate. Good to excellent yield, mild reaction conditions, as well as ease of operation and work-up are some advantages of the protocol.

Efficient multi-component synthesis of highly substituted imidazoles utilizing P2O5/SiO2 as a reusable catalyst

Phosphorus pentoxide supported on silica gel (P2O 5/SiO2) has been used as an efficient and reusable catalyst for the one-pot pseudo four-component synthesis of 2,4,5-trisubstituted imidazoles from benzil or benzoin, aldehydes, and ammonium acetate. It was also used for four-component preparation of 1,2,4,5-tetrasubstituted imidazoles from benzil or benzoin, aldehydes, primary amine, and ammonium acetate under thermal solvent-free conditions. The remarkable features of this new procedure are high conversions, cleaner reaction, simple experimental and work-up procedures and also the catalyst can be easily separated from the reaction mixture and reused several times without any loss of its activity.