72012-84-1

Upstream product

• 123-75-1 pyrrolidine 
• 50-00-0 formaldehyd 
• 18940-21-1 5,5-dimethyl-3-(phenylamino)cyclohex-2-en-1-one 
• 110-89-4 piperidine 
• 110-91-8 morpholine 
• 111-49-9 hexamethylene imine 
• 51407-84-2 5,5-dimethyl-2-(N-morpholinomethyl)-3-anilino-2-cyclohexen-1-one 
• 51407-82-0 3-Anilino-2-diethylaminomethyl-5,5-dimethyl-2-cyclohexen-1-on 
• 124-40-3 dimethyl amine 
• 109-89-7 diethylamine 
• 124-38-9 carbon dioxide 
• 76159-20-1 3-Anilino-2-hexamethyleniminomethyl-5,5-dimethyl-2-cyclohexen-1-on 
• 76159-19-8 3-Anilino-5,5-dimethyl-2-(1-pyrrolidinylmethyl)-2-cyclohexen-1-on 
• 74972-01-3 3-Anilino-2-dimethylaminomethyl-5,5-dimethyl-2-cyclohexen-1-on 

Relevant academic research and scientific papers

Reductive CO2Fixation via the Selective Formation of C-C Bonds: Bridging Enaminones and Synthesis of 1,4-Dihydropyridines

Herein, a selective tandem C-C bond-forming reaction with CO2 was developed to realize the bridging of enaminones and synthesis of 1,4-dihydropyridines, respectively. n-Butylamine significantly promoted this CO2 deoxymethylenation procedure catalyzed by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) and ZnCl2. The mechanism involving the formation of bis(silyl)acetal, nucleophilic addition, and amine elimination was also interpreted to clarify the bridging of two molecules of enaminones with CO2 and the generation of dihydropyridine derivatives.

Participation of Vinylogous Carbonamide Groups Through the Generation of Carbiminium Compounds

Mercury EDTA dehydrogenation with Mannich bases derived from enaminones of dimedone and having a cyclic amine part mostly shows a neighbouring participation.From aromatically substituted vinylogous amides lactamamides are produced, while aliphatic substit