726-10-3

Upstream product

• 1516-60-5 4-nitrophenyl azide 
• 108-88-3 toluene 
• 95-46-5 2-methylphenyl bromide 
• 104-04-1 N-(4-Nitrophenyl)acetamide 
• 94-69-9 2'-methylformanilide 
• 350-46-9 4-Fluoronitrobenzene 
• 7647-01-0 hydrogenchloride 
• 858502-01-9 N-(4-nitro-benzenesulfonyl)-N'-o-tolyl-guanidine 
• 100-02-7 4-nitro-phenol 
• 95-53-4 o-toluidine 
• 100-00-5 4-chlorobenzonitrile 
• 26760-22-5 methyl p-nitrobenzenesulphinate 
• 100-32-3 di(p-nitrophenyl) disulfide 
• 615-37-2 ortho-methylphenyl iodide 

Downstream Products

• 66311-46-4 N⁴-(2-methylphenyl) benzene-1,4-diamine 
• 1417726-08-9 1-(benzo[d][1,3]dioxol-5-yl)-3-((4-nitrophenyl)(o-tolyl)amino)propan-2-ol 

Relevant academic research and scientific papers

Diarylamine Synthesis via Desulfinylative Smiles Rearrangement

Diarylamines are obtained directly from sulfinamides through a novel rearrangement sequence. The transformation is transition metal-free and proceeds under mild conditions, providing facile access to highly sterically hindered diarylamines that are otherw

N-(4-indolyl) N-heterocyclic carbene palladium complex and application thereof

The invention discloses N-(4-indolyl) N-heterocyclic carbene palladium complexes of which the chemical structural general formula is shown in the specification. The palladium complex provided by the invention can be used for catalyzing cross coupling reactions such as Suzuki-Miyaura coupling, Buchwald-Hartwig reaction and the like.

Ligand-Enabled Gold-Catalyzed C(sp2)-N Cross-Coupling Reactions of Aryl Iodides with Amines

The first example of ancillary (P,N)-ligand-enabled gold-catalyzed C-N cross-coupling reactions of aryl iodides with amines is reported. The high generality of the reaction in de novo synthesis, late-stage modifications, and cascade processes to access functionalized indolinones and carbazoles underscores the synthetic potential of the presented strategy. Monitoring the reaction with ESI-HRMS and NMR provided strong evidence for the in situ formation of putative high valent Au(III) intermediates.

Microwave assisted synthesis, characterization and antimicrobial activity of 10H-phenothiazine derivatives

A new environmental benign method for synthesis of phenothiazine derivatives using microwave irradiation has reported. A mixture of o-substituted aromatic amine and p-substituted phenol converted into biphenyl amine derivative using microwave irradiation.

Smiles rearrangement for the synthesis of diarylamines

A protocol for the one-pot synthesis of diarylamines via Smiles rearrangement under microwave irradiation has been developed. Various diarylamines were effectively synthesized starting from readily available substituted phenols, arylamines and chloroacetyl chloride in moderate to good yields (58-92%). ARKAT-USA, Inc.

Process for the production of nitrodiarylamines

A process for the production of nitrodiarylamines by the reaction of a nitroarene with an aromatic primary amine in a suitable solvent and in the presence of a base capable of abstracting a proton from said aromatic primary amine, is disclosed. The reaction is carried out at a reaction temperature of 20-70°C over a period of 6-24 hours and in a substantially oxygen-free atmosphere. The produced nitrodiaryl amines are useful as intermediates for the production of dyestuffs and rubber antidegradants.

ALIPHATIC C-H, N-INSERTION VERSUS AROMATIC N-SUBSTITUTION IN THE REACTION OF ARYLNITRENIUM-BORON TRIFLUORIDE COMPLEXES WITH METHYLATED BENZENES

The boron trifluoride promoted decomposition of a number of substituted phenyl azides in toluene, para-xylene, meta-xylene or mesitylene at 60 gradC, leads preferentially to N-benzylamines or diarylamines depending on both ring substituent effect and nucleophilic character of the solvent.

N- and C-Attacks of Phenylnitrenium Ions Generated from Phenyl Azides in the Presence of Trifluoroacetic Acid and/or Trifluoromethanesulphonic Acid

Phenylnitrenium ions were generated from phenyl azides in the presence of trifluoroacetic acid (TFA) and/or trifluoromethanesulphonic acid (TFSA).Unsubstituted phenylnitrenium ions and those with an electron-withdrawing group such as NO2 or CN undergo aromatic N-substitution, whereas those with an electron-donating group such as Me, OMe, CH2Ph, or Ph undergo C-substitution, hydrogen abstraction, and tar formation.The special character of TFA and TFSA as compared with other acids is discussed.

Process for the preparation of 4-nitrodiphenylamines

The invention relates to a process for the preparation of 4-nitrodiphenylamines by the reaction of halogenonitrobenzenes with primary aromatic amines in the presence of copper or a copper compound, a neutralizing agent and a cyclic diaza compound.