7305-01-3

Upstream product

• 95-57-8 2-monochlorophenol 
• 33842-02-3 dichloromethylenedimethyliminium chloride 
• 108-95-2 phenol 
• 95-56-7 2-hydroxybromobenzene 
• 6969-90-0 phenyl N,N-dimethylcarbamate 
• 1360939-08-7 2-deuterio-phenyl dimethylcarbamate 
• 23951-01-1 <2-D>-phenol 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 

Downstream Products

• 1309752-13-3 butyl (E)-3-{3-chloro-2-[(dimethylcarbamoyl)oxy]phenyl}acrylate 
• 1341217-59-1 (E)-ethyl 3-{3-chloro-2-[(N,N-dimethylcarbamoyl)oxy]phenyl}acrylate 
• 14863-58-2 2,6-dichlorophenyl dimethylcarbamate 
• 87-65-0 2,6-Dichlorophenol 
• 2040-88-2 2-bromo-6-chlorophenol 
• 1534364-16-3 2-bromo-6-chlorophenyl dimethylcarbamate 
• 1631050-48-0 2-chloro-6-hydroxyphenyl dimethylcarbamate 

Relevant academic research and scientific papers

Pd(II) catalyzed ortho C-H iodination of phenylcarbamates at room temperature using cyclic hypervalent iodine reagents

A novel approach to access ortho iodinated phenols using cyclic hypervalent iodine reagents through palladium(II) catalyzed C-H activation has been developed through weak coordination. The reaction showed excellent regioselectivity, reactivity and good functional group tolerance. A unique mechanism was proposed.

Room-temperature Pd-catalyzed C-H chlorination by weak coordination: One-pot synthesis of 2-chlorophenols with excellent regioselectivity

A room-temperature Pd(ii)-catalyzed regioselective chlorination reaction has been developed for a facile one-pot synthesis of a broad range of 2-chlorophenols. The reaction demonstrates an excellent regioselectivity and reactivity for C-H chlorination. This reaction represents one of the rare examples of mild C-H functionalization at ambient temperature.

A general approach towards catechol and pyrogallol through ruthenium- and palladium-catalyzed C-H hydroxylation by weak coordination

An efficient ruthenium(II)- and palladium(II)-catalyzed C-H hydroxylation of aryl carbamates has been developed for the facile synthesis of catechols and pyrogallols. The reaction demonstrates excellent reactivity, regio- and chemoselectivity, good functional group compatibility and high yields. The practicality of this method has been proved by a gram-scale synthesis.

Rhodium-catalyzed selective C-H activation/olefination of phenol carbamates

Rh(III)-catalyzed ortho C-H activation/olefination of phenol carbamates has been developed. High regioselectivity is observed with a range of phenol carbamates enabling efficient coupling with acrylates and styrenes. This reaction exhibits different react

CHLORINATING CHARACTERISTICS OF THE COMPLEX OF N,N-DIMETHYLDICHLOROMETHYLENEIMINIUM CHLORIDE WITH CHLORINE

The chlorinating characteristics of the complex (I) of N,N-dimethyldichloromethyleneiminium chloride with chlorine were studied for the case of its reactions with olefins (1-hexene, cyclohexene, tetrachloroethylene), unsaturated alcohols (allyl alcohol), and phenols (phenol, p-cresol).It was found that the ionic chlorination of the olefins by the complex takes place at high rates and with a high degree of selectivity.With the hydroxy compounds there are parallel reactions, in which the chlorinating characteristics of the complex (I) and the reactivity of the N,N-dimethyldichloromethyleneiminium chloride appear.Chlorination of the phenols by the complex (I) takes place at the ortho position, and this leads to the formation of di(o-chloroacyl) carbonates (with the complex and the phenol in a ratio of 1:2) or o-chloroaryl dimethylcarbamates (with the reagents in a ratio of 1:1).