82816-76-0

Usage

Uses

Used in Biochemical Research:
BOC-PHE-PHE-GLY-OH is used as a research tool for studying the properties and functions of specific amino acid sequences in biological systems. The unique sequence of phenylalanine and glycine allows researchers to investigate their interactions with other biomolecules and their potential roles in various biological processes.
Used in Pharmaceutical Development:
BOC-PHE-PHE-GLY-OH is used as a potential therapeutic agent in the development of new drugs. The specific sequence of amino acids may exhibit biological activities that can be harnessed for treating various diseases and conditions. Further research and optimization of the peptide sequence can lead to the discovery of novel pharmaceutical compounds.
Used in Drug Delivery Systems:
BOC-PHE-PHE-GLY-OH can be used as a component in drug delivery systems to improve the efficacy and targeting of therapeutic agents. The peptide sequence may be modified or conjugated to other molecules to enhance their delivery to specific cells or tissues, increasing the therapeutic potential of the drug while minimizing side effects.
Used in Peptide Synthesis:
BOC-PHE-PHE-GLY-OH serves as a building block in the synthesis of larger peptides or proteins. The BOC protecting group at the N-terminus allows for controlled peptide synthesis, preventing unwanted side reactions during the assembly process. This peptide can be used as a starting point for the development of more complex peptide-based therapeutics or diagnostic agents.

InChI:InChI=1/C25H31N3O6/c1-25(2,3)34-24(33)28-20(15-18-12-8-5-9-13-18)23(32)27-19(22(31)26-16-21(29)30)14-17-10-6-4-7-11-17/h4-13,19-20H,14-16H2,1-3H3,(H,26,31)(H,27,32)(H,28,33)(H,29,30)

Upstream product

• 40099-25-0 Boc-Phe-Phe-NH-NH₂ 
• 56-40-6 glycine 
• 41041-68-3 L-phenylalanyl-glycine ethyl ester*HCl 
• 30189-51-6 ethyl (N-tert-butoxycarbonyl-L-phenylalanyl)glycinate 
• 139151-99-8 H-Phe-Gly-ONb*HCl 
• 7625-57-2 methyl 2-((2S)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanamido)acetate 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 13122-89-9 (S)-methyl 2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-3-phenylpropanoate 
• 64698-97-1 Boc-Phe-Phe-Gly-OBzl 
• 139152-00-4 Boc-Phe-Phe-Gly-ONb 
• 62307-54-4 Boc-Phe-Phe-Gly-OEt 
• 66876-64-0 Boc-Phe-Phe-Gly-OMe 

Downstream Products

• 73148-99-9 N-t-Boc-Phe-Phe-Gly-Leu-Met-NH₂ 
• 1620161-93-4 (6S,9S)-benzyl 6,9-dibenzyl-2,2,14-trimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-92-3 (6S,9S,15S)-ethyl 15-((1H-imidazol-5-yl)methyl)-6,9-dibenzyl-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-91-2 (6S,9S,15S)-methyl 15-(4-aminobutyl)-6,9-dibenzyl-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620162-40-4 C₃₂H₄₅N₅O₇ 
• 1620161-90-1 (6S,9S,15S)-methyl 6,9-dibenzyl-15-((R)-1-hydroxyethyl)-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-89-8 (6S,9S,15S)-methyl 15-(2-amino-2-oxoethyl)-6,9-dibenzyl-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-88-7 (6S,9S,15S)-methyl 15-((1H-indol-3-yl)methyl)-6,9-dibenzyl-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-87-6 (6S,9S,15S)-methyl 6,9-dibenzyl-15-(3-guanidinopropyl)-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-86-5 (6S,9S,15S)-benzyl 6,9-dibenzyl-15-(hydroxymethyl)-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-85-4 (6S,9S,15S)-6,9-dibenzyl-15-((benzyloxy)carbonyl)-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazaheptadecan-17-oic acid 
• 1620161-84-3 (6S,9S,15S)-benzyl 6,9-dibenzyl-15-(4-hydroxybenzyl)-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-83-2 (6S,9S,15S)-tert-butyl 15-(3-amino-3-oxopropyl)-6,9-dibenzyl-2,2-dimethyl-4,7,10,13-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oate 
• 1620161-82-1 (6S,9S)-S-4-nitrophenyl 6,9-dibenzyl-2,2-dimethyl-4,7,10-trioxo-3-oxa-5,8,11-triazatridecane-13-thioate 

Relevant academic research and scientific papers

Isolation, structure and synthesis of mahafacyclin B, a cyclic heptapeptide from the latex of Jatropha mahafalensis

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Analogues of the C-terminal hexapeptide of substance P have been synthesized in which each amino-acid residue was replaced by the bulky and strong lipophilic residue Asp(OBzl). The amino-acid residue of other selected places has also been replaced by Glu(

SYNTHESIS OF A NUMBER OF COMBINED ANALOGUES OF SUBSTANCE P AND LITORIN

With the aim of obtaining new biologically active compounds, we have synthesized nine combined peptides (I)-(IX) consisting of combinations of the C-terminal tripeptide litorin and the hydrophobic central fragments of substance P, and also modified analogues of them.The synthesis of these compounds was achieved by the methods of classical peptide chemistry with the condensation of their N-terminal moieties with the C-terminal tripeptide H-His-Phe-Met-NH2.

SYNTHESIS OF FOUR ANALOGS OF 6-11 SUBSTANCE P FRAGMENT OF INCREASED WATER SOLUBILITY

Four analogs of 6-11 Substance P fragment with histidine in various positions were synthesized by the conventional method.The peptides obtained exhibit a 100-200 times higher solubility in water than 6>SP6-11 analog, but only on

SYNTHESIS OF PENTAPEPTIDES RELATED BOTH TO SUBSTANCE P C-TERMINAL FRAGMENT AND MET-ENKEPHALIN

Six pentapeptide amides related both to Substance P C-terminal fragment and to Met-enkephalin have been synthesized.Syntheses were effected by coupling fragments 3 + 2 in solution.The DCC + HOBt method was used for synthesis of peptide fragments and final