7314-06-9Relevant articles and documents
Effect of the Linking Group on the Thermoelectric Properties of Poly(Schiff Base)s and Their Metallopolymers
Li, Jiahua,Wang, Zitong,Sun, Zelin,Xu, Linli,Wong, Wai-Yeung
, p. 1911 - 1917 (2021/06/21)
As polymer-based thermoelectric (TE) materials possess attractive features such as light weight, flexibility, low toxicity and ease of processibility, an increasing number of conducting polymers and their composites with high TE performances have been developed in recent years. Up to date, however, the research focusing on the structure-performance relationship remains rare. In this paper, two series of poly(Schiff base)s with either C=C or C≡C linker and their metallopolymers were synthesized and doped with single-walled carbon nanotubes to evaluate how the linking groups affected the TE properties of the resulting composites. Apart from the effect exerted by the morphology, experimental results suggested that the linkers played a key role in determining the band gaps, preferred molecular conformation and extent of conjugation of the polymers, which became key factors that influenced the TE properties of the resulting materials. Additionally, upon coordination with transition metal ions, the TE properties could be tuned readily.
Single-molecule conductance in a unique cross-conjugated tetra(aminoaryl)ethene
Medina Rivero, Samara,García Arroyo, Paloma,Li, Liang,Gunasekaran, Suman,Stuyver, Thijs,Manche?o, María José,Alonso, Mercedes,Venkataraman, Latha,Segura, José L.,Casado, Juan
supporting information, p. 591 - 594 (2021/01/29)
A 1,1,2,2-tetrakis(4-aminophenyl)ethene with three paths of π-conjugation, linear-cis, linear-trans and a cross-conjugation, has been prepared. The molecule is able to bind to gold electrodes forming molecular junctions for single-molecule conductance measurements. Only two regimes of conduction are found experimentally. The modelling of the conductance allows to assign them to through-bond transmission in the linear case, while the cross-conjugated channel is further assisted by through-space transmission, partially alleviating the destructive quantum interference. This journal is
In Vitro, In Silico, and In Vivo Analyses of Novel Aromatic Amidines against Trypanosoma cruzi
Santos, Camila C.,Lionel, Jéssica R.,Peres, Raiza B.,Batista, Marcos M.,Da Silva, Patrícia B.,De Oliveira, Gabriel M.,Da Silva, Cristiane F.,Batista, Denise G. J.,Souza, Sandra Maria O.,Andrade, Carolina H.,Neves, Bruno J.,Braga, Rodolpho C.,Patrick, Donald A.,Bakunova, Svetlana M.,Tidwell, Richard R.,Soeiro, Maria de Nazaré C.
supporting information, (2018/02/06)
Five bis-arylimidamides were assayed as anti-Trypanosoma cruzi agents by in vitro, in silico, and in vivo approaches. None were considered to be pan-assay interference compounds. They had a favorable pharmacokinetic landscape and were active against trypomastigotes and intracellular forms, and in combination with benznidazole, they gave no interaction. The most selective agent (28SMB032) tested in vivo led to a 40% reduction in parasitemia (0.1 mg/kg of body weight/5 days intraperitoneally) but without mortality protection. In silico target fishing suggested DNA as the main target, but ultrastructural data did not match.
Molecular probes for imaging of myelin
-
, (2018/06/18)
A molecular probe for labeling myelin includes a fluorescent trans-stilbene derivative.
HCV NS5A replication complex inhibitors. Part 4.1 optimization for genotype 1a replicon inhibitory activity
St. Laurent, Denis R.,Serrano-Wu, Michael H.,Belema, Makonen,Ding, Min,Fang, Hua,Gao, Min,Goodrich, Jason T.,Krause, Rudolph G.,Lemm, Julie A.,Liu, Mengping,Lopez, Omar D.,Nguyen, Van N.,Nower, Peter T.,O'Boyle, Donald R.,Pearce, Bradley C.,Romine, Jeffrey L.,Valera, Lourdes,Sun, Jin-Hua,Wang, Ying-Kai,Yang, Fukang,Yang, Xuejie,Meanwell, Nicholas A.,Snyder, Lawrence B.
, p. 1976 - 1994 (2014/04/03)
A series of symmetrical E-stilbene prolinamides that originated from the library-synthesized lead 3 was studied with respect to HCV genotype 1a (G-1a) and genotype 1b (G-1b) replicon inhibition and selectivity against BVDV and cytotoxicity. SAR emerging f
A 2:2 stilbeneboronic acid-γ-cyclodextrin fluorescent ensemble highly selective for glucose in aqueous solutions
Wu, Xin,Lin, Li-Rong,Huang, Yan-Jun,Li, Zhao,Jiang, Yun-Bao
, p. 4362 - 4364 (2012/06/15)
By designing a long and hydrophobic stilbeneboronic acid (STDBA) and allowing it to be included within the cavity of γ-cyclodextrin (γ-CyD) we succeeded in developing a fluorescent 2:2 STDBA-γ-CyD ensemble that shows a selective and sensitive response toward glucose in aqueous solutions, with satisfactory application in artificial urine samples. The Royal Society of Chemistry 2012.
MOLECULAR PROBES FOR IMAGING OF MYELIN
-
, (2011/08/08)
A molecular probe for labeling myelin includes a fluorescent trans-stilbene derivative.
Thermoreversible covalent self-assembly of oligo(p-phenylenevinylene) bridged gold nanoparticles
Liu, Xiaofeng,Liu, Huibiao,Zhou, Weidong,Zheng, Haiyan,Yin, Xiaodong,Li, Yuliang,Guo, Yanbing,Zhu, Mei,Ouyang, Canbin,Zhu, Daoben,Xia, Andong
experimental part, p. 3179 - 3185 (2010/12/18)
Organic-inorganic hybrids have been fabricated through mild Diels-Alder cross-linking between maleimide bearing oligo(p-phenylenevinylene) (OPV) and furan functionalized gold nanoparticles with, diameter smaller than 2 nm. The OPV ligands afford strong reaction, ability toward furan group due to their maleimide moieties. These small gold nanoparticles form close-packed homogeneous hybrids with well-defined interfaces by incorporating OPV ligands in solutions. Covalent assembly and disassembly of gold nanoparticles can be achieved by repeated thermal stimuli on as-obtained hybrids, which can be monitored by fluorescence changes of OPVs and surface plasmon resonance absorption. Moreover, the dramatic photophysical properties and assembly behavior of these hybrids allow this procedure to be performed as a smart assay for monitoring the process of the Diels-Alder reaction.
Molecular probes for imaging myelinated white matter in CNS
Wu, Chunying,Wei, Jinjun,Tian, Donghua,Feng, Yue,Miller, Robert H.,Wang, Yanming
experimental part, p. 6682 - 6688 (2009/11/30)
Abnormalities and changes in myelination in the brain are seen in many neurodegenerative disorders such as multiple sclerosis (MS). Direct detection and quantification of myelin content in vivo is desired to facilitate diagnosis and therapeutic treatments of myelin-related diseases. The imaging studies require use of myelin-imaging agents that readily enter the brain and selectively bind to myelinated regions. For this purpose, we have systematically evaluated a series of stilbene derivatives as myelin imaging agents. Spectrophotometry-based and radioligand-based binding assays showed that these stilbene derivatives exhibited relatively high myelin-binding affinities. In vitro myelin staining exhibited that the compounds selectively stained intact myelinated regions in wild type mouse brain. In situ tissue staining demonstrated that the compounds readily entered the mouse brain and selectively labeled myelinated white matter regions. These studies suggested that these stilbene derivatives can be used as myelin-imaging probes to monitor myelin pathology in vivo.
Gelation ability of novel oxamide-based derivatives bearing a stilbene as a photo-responsive unit
Miljanic, Snezana,Frkanec, Leo,Meic, Zlatko,Zinic, Mladen
, p. 1323 - 1334 (2007/10/03)
Oxamide-based derivatives containing one or two oxamide moieties coupled to the 4- or 4,4′-positions of cis- and transstilbene have been synthesised. In order to modulate the solvent gelation tendencies, a series of derivatives with modified terminal functions were prepared from them. The transstilbene dioxamide-based derivatives were found to be sparingly soluble or insoluble in water and in organic solvents, whereas the trans-stilbene monooxamide-based derivatives are soluble in most organic solvents. Incorporation of a C 12 alkyl chain in the structure of the latter compounds results in a decreased solubility but in an increased gelation tendency of the substances. The ethyl ester oxamide-based derivative trans-3a and the amino acid oxamide-based derivative trans-3e act as efficient gelators of various organic solvents. In contrast, cis-3a shows a poor gelation ability or none at all, owing to its good solubility. Considering the difference in gelation abilities of the compounds trans-3a and cis-3a and the photo-responsive conformational changes of the stilbene part of the molecule, a controlled gelation by light was achieved. FT-IR and 1H NMR spectroscopic measurements support the view that hydrogen bonding between the oxamide fragments plays an important role in gel formation. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
