73842-48-5

Basic information

• Product Name: BENZYL-BIPHENYL-4-YL-AMINE
• Synonyms: BENZYL-BIPHENYL-4-YL-AMINE
• CAS NO: 73842-48-5
• Molecular Formula: C₁₉H₁₇N
• Molecular Weight: 259.34498
• Mol File: 73842-48-5.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 422.4°C at 760 mmHg
• Flash Point: 223.9°C
• Appearance: /
• Density: 1.104g/cm³
• Vapor Pressure: 2.42E-07mmHg at 25°C
• Refractive Index: 1.643
• CAS DataBase Reference: BENZYL-BIPHENYL-4-YL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL-BIPHENYL-4-YL-AMINE(73842-48-5)
• EPA Substance Registry System: BENZYL-BIPHENYL-4-YL-AMINE(73842-48-5)

Safety Data

• Hazardous Substances Data: 73842-48-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H17N/c1-3-7-16(8-4-1)15-20-19-13-11-18(12-14-19)17-9-5-2-6-10-17/h1-14,20H,15H2

Upstream product

• 92-67-1 4-phenylalanine 
• 100-52-7 benzaldehyde 
• 2350-89-2 p-vinylbiphenyl 
• 622-79-7 benzyl azide 
• 100-42-5 styrene 
• 6554-98-9 trans-4-Hydroxystilbene 
• 31656-91-4 4-azidobiphenyl 
• 100-46-9 benzylamine 
• 128965-94-6 N-Benzyl-2-(biphenyl-4-yloxy)-2-methyl-propionamide 
• 13924-28-2 N-benzylidene-4-phenylaniline 
• 92-93-3 1-phenyl-4-nitrobenzene 
• 108-88-3 toluene 
• 2051-62-9 4'-biphenyl chloride 
• 92-66-0 4-bromo-1,1'-biphenyl 

Downstream Products

• 462631-33-0 N,N'-dibenzyl-N,N'-di-4-biphenylylbenzidine 
• 854235-33-9 benzyl-biphenyl-4-yl-(β-nitro-isobutyl)-amine 

Relevant articles and documents

Method for synthesizing heteroatom- substituted aromatic compound from styrene compound

The invention discloses a method for synthesizing a heteroatom-substituted aromatic compound from a styrene compound, which comprises the following steps of: mixing a styrene compound with a general formula (I) and a heteroatom-containing compound with a general formula (II), and reacting in the presence of an acid additive and an organic solvent to obtain a heteroatom-substituted compound with ageneral formula (III). According to the synthesis method disclosed by the invention, a large amount of styrene compounds are used as raw materials and react to generate aromatic amine or phenol compounds under the action of no metal catalysis; and compared with the traditional aromatic amine and phenol synthesis method, the method has the advantages of high yield, simple conditions, low waste discharge amount, no metal participation, simple reaction equipment, easiness in industrial production and the like.

Direct electrochemical reductive amination between aldehydes and amines with a H/D-donor solvent

A novel electrochemical synthesis protocol has been achieved for reductive amination between aldehydes and amines in undivided cells at room temperature. Under metal-free and external-reductant-free electrolysis conditions, various important secondary amine products are obtained in moderate-to-high yields. Deuterium-labeling experiments have demonstrated that low-toxicity DMSO acts both as a solvent and a H-donor in the reaction. On this basis, various deuterium-labeled products with good-to-excellent D-incorporation have been synthesized by using DMSO-d6 as a solvent. Furthermore, a molecule with GR-antagonistic activity has been synthesized through further sulfonylation.

Iron-Catalyzed Nitrene Transfer Reaction of 4-Hydroxystilbenes with Aryl Azides: Synthesis of Imines via C=C Bond Cleavage

C=C bond breaking to access the C=N bond remains an underdeveloped area. A new protocol for C=C bond cleavage of alkenes under nonoxidative conditions to produce imines via an iron-catalyzed nitrene transfer reaction of 4-hydroxystilbenes with aryl azides is reported. The success of various sequential one-pot reactions reveals that the good compatibility of this method makes it very attractive for synthetic applications. On the basis of experimental observations, a plausible reaction mechanism is also proposed.