7402-45-1

Basic information

• Product Name: 2,2,2-tribromo-1-phenylethanone
• Synonyms: ethanone, 2,2,2-tribromo-1-phenyl-
• CAS NO: 7402-45-1
• Molecular Formula: C₈H₅Br₃O
• Molecular Weight: 356.8367
• Mol File: 7402-45-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 278.3°C at 760 mmHg
• Flash Point: 79.8°C
• Density: 2.222g/cm³
• Vapor Pressure: 0.0043mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: 2,2,2-tribromo-1-phenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-tribromo-1-phenylethanone(7402-45-1)
• EPA Substance Registry System: 2,2,2-tribromo-1-phenylethanone(7402-45-1)

Safety Data

• Hazardous Substances Data: 7402-45-1(Hazardous Substances Data)

Usage

General Description

2,2,2-tribromo-1-phenylethanone is a chemical compound with the molecular formula C8H6Br3O. It is a yellow crystalline solid with a strong, pungent odor. 2,2,2-tribromo-1-phenylethanone is often used as a flame retardant in various industrial applications due to its ability to inhibit the spread of fire. It is also used as a precursor in the synthesis of other organic compounds. Additionally, 2,2,2-tribromo-1-phenylethanone is known to be harmful if ingested or inhaled, and can cause irritation to the skin and eyes. Therefore, proper safety precautions should be taken when handling this chemical.

Upstream product

• 127-09-3 sodium acetate 
• 98-86-2 acetophenone 
• 100-42-5 styrene 
• 2425-28-7 2-Bromo-1-phenylethanol 
• 70-11-1 α-bromoacetophenone 
• 1201-93-0 1-phenyl-3-dimethylaminoprop-2-enone 
• 100-52-7 benzaldehyde 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 637-44-5 phenylpropyolic acid 
• 536-74-3 phenylacetylene 
• 38158-81-5 phenyl(tribromomethyl)carbinol 
• 2170-06-1 1-Phenyl-2-(trimethylsilyl)acetylene 
• 13665-04-8 2,2-dibromoacetophenone 
• 1600-27-7 mercury(II) diacetate 

Downstream Products

• 40032-49-3 N,N'-methylenedipyridinium bromide 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 99-73-0 para-bromophenacyl bromide 
• 136-60-7 benzoic acid, butyl ester 
• 13665-04-8 2,2-dibromoacetophenone 
• 5524-55-0 n-butyl 2-oxo-2-phenylacetate 
• 70-11-1 α-bromoacetophenone 
• 38158-81-5 phenyl(tribromomethyl)carbinol 
• 120-51-4 benzoic acid benzyl ester 
• 1485-70-7 N-benzylbenzamide 
• 4743-74-2 (R)-2-phenyl-pent-4-en-2-ol 
• 3389-54-6 n-benzoylpyrrolidine 
• 4909-81-3 s-butyl benzoate 
• 95653-53-5 sec-butyl 2-oxo-phenylacetate 

Relevant articles and documents

Efficient and widely applicable oxidation method of tribromomethyl carbinols with PCC

An efficient and widely applicable oxidation method of tribromomethyl carbinols in the presence of pyridinium chlorochromate has been developed with excellent yields up to 96%. This method was well applied for the oxidation of a variety of aromatic, aliph

Selective Debromination of α,α,α-Tribromomethylketones with HBr–H2O Reductive Catalytic System

A debromination of α,α,α-tribromomethylketones is developed for chemoselective synthesis of α-mono- and α,α-dibromomethylketones with high selectivity under H2O–HBr reductive conditions. This method offers an efficient and direct way to synthesize α-mono or α,α-dibromomethylketone compounds in high to excellent yields through the process of HBr self-circulation in water.

Decarboxylative Tribromination for the Selective Synthesis of Tribromomethyl Ketone and Tribromovinyl Derivatives

Tribromomethyl ketone and tribromovinyl derivatives were selectively prepared from the decarboxylative tribromination. The reaction between propiolic acid derivatives and dibromoisocyanuric acid (DBCA)/H2O afforded predominantly a tribromomethyl ketone derivative in the presence of AgOAc (10 mol%). When the same reaction was conducted with 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) instead of AgOAc, tribromovinyl derivatives were exclusively formed in good yields. It was found that ethynyl bromide is an intermediate. (Figure presented.).