74119-61-2Relevant academic research and scientific papers
Synthesis of a New Family of 1,1-Diazidoethenes: One-Pot Construction of 4-Azido-1,2,3-triazoles via Nitrene Cyclization
Shastin, Alexey V.,Tsyrenova, Biligma D.,Sergeev, Pavel G.,Roznyatovsky, Vitaly A.,Smolyar, Ivan V.,Khrustalev, Victor N.,Nenajdenko, Valentine G.
, p. 7803 - 7806 (2018)
The reaction of 4,4-dichloro-1,2-diazabuta-1,3-dienes with sodium azide has been studied and found to provide straightforward access to extremely rare 1,1-bisazides. It was demonstrated that these highly unstable compounds are prone to eliminate the N2 molecule to cyclize into 4-azido-1,2,3-triazoles bearing two aryl (heteroaryl) groups at positions 2 and 5. The formation of bisazides was confirmed by their trapping with cyclooctyne and B3LYP calculations. Most likely, the elimination of nitrogen to form an intermediate nitrene is facilitated by the aza group via anchimeric-like participation. The reaction was found to be very general for the highly efficient synthesis of various 4-azidotriazoles. It was demonstrated that these heterocycles are highly attractive building blocks for subsequent preparation of 1,2,3-triazole-derived compounds.
A novel synthesis of 4-amino-5-aryl-2-phenyl-2H-1,2,3-triazoles from α-oxonitriles
Rai, B. J.,Lakhan, R.
, p. 595 - 596 (2007/10/02)
4-Amino-5-aryl-2-phenyl-2H-1,2,3-triazoles (2) are obtained in good yields when α-oxonitriles (1) are treated with phenylhydrazine.The products have been characterised on the basis of analytical and spectral (IR and PMR) data.The mechanism of their formation is also discussed.
The Simpliest Biformazan: 1,1',5,5'-Tetraphenyl-3,3'-biformazan
Neugebauer, Franz Alfred,Fischer, Hans
, p. 1226 - 1234 (2007/10/02)
The synthesis and the properties of the biformazan 9 are reported.Dehydrogenation of 9 yields the betain 20, which like the salt 21 represents the middle oxidation state between the biformazan 9 and the bis(tetrazolium salt) 22.
