61308-15-4

Upstream product

• 23572-06-7 phenyl(5-phenyl-1,2,4-oxadiazol-3-yl)methanone 
• 618-40-6 1-Methyl-1-phenylhydrazine 
• 81569-69-9 (E)-N-methyl-N-phenylhydrazone 
• 100-63-0 phenylhydrazine 
• 59785-50-1 (Z)-phenylhydrazone 3-benzoyl-5-phenyl-1,2,4-oxadiazole 
• 59785-50-1 (E)-3-benzoyl-5-pgenyl-1,2,4-oxadiazole phenylhydrazone 

Downstream Products

• 74119-61-2 4-amino-2,5-diphenyl-2H-1,2,3-triazole 

Relevant academic research and scientific papers

Host-guest interactions between β-cyclodextrin and the (Z)-phenylhydrazone of 3-benzoyl-5-phenyl-1,2,4-oxadiazole: The first kinetic study of a ring-ring interconversion in a "confined environment"

The effect of β-cyclodextrin (β-CD) on the mononuclear heterocyclic rearrangement of the (Z)-phenylhydrazone of 3-benzoyl-5-phenyl-1,2,4-oxadiazole (1) in aqueous borate buffer at pH = 9.6 has been analyzed at temperatures ranging from 293.15 to 313.15 K.

Monomolecular Heterocyclic Rearrangements. Part 7. Evidence for General Base Catalysis in the Rearrangement of the Z-Phenylhydrazone of 3-Benzoyl-5-phenyl-1,2,4-oxadiazole into 2,5-Diphenyl-4-benzoylamino-1,2,3-triazole in Dioxan-Water

The title reaction has been studied at various pS+ and buffer concentrations.Kinetic constants for uncatalysed and catalysed pathways have been calculated.A mechanism for the rearrangement is offered.

Elucidating chemical reactivity and transition state of mononuclear rearrangement of heterocycles through the use of compartimentalized micellar media

The present comprehensive kinetic investigation in micellar systems deepens and broadens the knowledge of mononuclear rearrangement of heterocycles (MRH) of Z-phenylhydrazone of 3-benzoyl-5-phenyl-1,2,4-oxadiazole, reaction already carried out in different reaction media. As a matter of fact the use of four types of micelles different for charge, shape and polarity has allowed us to evaluate the role of micellar systems, as reaction media, on the rate of MRH and to quantify their catalytic effect. Moreover, the data obtained have enabled us to draw some intriguing conclusions on the localization of the substrate in the micelles, the transition state structure and the driving force of the reaction.

Can the absence of solvation of neutral reagents by ionic liquids be responsible for the high reactivity in base-assisted intramolecular nucleophilic substitutions in these solvents?

The kinetics of the rearrangement of the Z-phenylhydrazone of 3-benzoyl-5-phenyl-1,2,4-oxadiazole (1a) into the relevant 4-benzoylamino-2,5- diphenyl-1,2,3-triazole (2a) induced by amines have been studied in two room-temperature ionic liquids (IL-1, [BMI

On the characterization of some [bmim][X]/co-solvent binary mixtures: a multidisciplinary approach by using kinetic, spectrophotometric and conductometric investigations

In order to study the intrinsic characteristics and to evaluate the structural variations determined by the addition of a co-solvent to 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]) we examined the behaviour of some probes in [bmi

Room temperature ionic liquids structure and its effect on the mononuclear rearrangement of heterocycles: An approach using thermodynamic parameters

The kinetics of the rearrangement of the Z-phenylhydrazone of 3-benzoyl-5-phenyl-1,2,4-oxadiazole (1) inti the relevant 4-benzoylamino-2,5- diphenyl-1,2,3-triazole (2) induced by amines have been studied in five room-temperature ionic liquids (RTILs) at d

Mononuclear Heterocyclic Rearrangements. Part 9. A Kinetic Study of the Rearrangement of the Z-Phenylhydrazone of 3-Benzoyl-5-phenyl-1,2,4-oxadiazole into 4-Benzoylamino-2,5-diphenyl-1,2,3-triazole in Methanol, Dioxan, Ethyl Acetate, and Acetonitrile

The kinetics of the title reactions have been measured at various piperidine concentrations.The results obtained show that in all the solvents studied the rearrangements occur through a bimolecular reaction pathway involving one molecule of piperidine (k

Task specific dicationic ionic liquids: Recyclable reaction media for the mononuclear rearrangement of heterocycles

Nine functionalized dicationic ionic liquids were used to study the base catalyzed mononuclear rearrangement of (Z)-phenylhydrazone of 3-benzoyl-5-phenyl-1,2,4-oxadiazole into the corresponding triazole at 363 K. Ionic liquids were characterized by the pr

Photochemical isomerization of aryl hydrazones of 1,2,4-oxadiazole derivatives into the corresponding triazoles

The photochemical version of the Boulton-Katritzky reaction has been studied, examining the behaviour of the arylhydrazones of 3-benzoyl-5-X-1,2,4- oxadiazoles. The effect of several modifications of the substrates structure (the E and/or Z structures of

Binary mixtures of ionic liquids: A joint approach to investigate their properties and catalytic ability

The growing interest in the properties and applications of ionic liquids has recently led to research into the possibility of using their binary mixtures. This work reports on the effects of binary mixtures of ionic liquids on the outcome of organic react