74327-04-1Relevant articles and documents
Urea-induced acid amplification: A new approach for metal-free insertion chemistry
Couch, Erica D.,Auvil, Tyler J.,Mattson, Anita E.
supporting information, p. 8283 - 8287 (2014/07/08)
The enhanced catalytic activity of difluoroboronate ureas proved to be essential as an acidity amplifier to promote metal-free O-H and S-H insertion reactions of α-aryldiazoacetates in high yield. This methodology was found to be generally applicable to a
Kinetic resolution of mandelate esters via stereoselective acylation catalyzed by lipase PS-30
Chen, Peiran,Yang, Wenhong
supporting information, p. 2290 - 2294 (2014/04/17)
By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic mandelate esters has been achieved via stereoselective acylation. The value of kinetic enantiomeric ratio (E) reached up to 197.5. Substituent effect is briefly discussed.
Photochemical reactions of alkyl phenylglyoxylates
Hu, Shengkui,Neckers, Douglas C.
, p. 6407 - 6415 (2007/10/03)
Three new photoproducts, ethyl O-benzoyl mandelate (5a), ethyl O-acetylmandelate (6a), and biphenyl triketone (7a) are isolated and identified in the reactions of ethyl phenylglyoxylate (1a) in benzene. Quantum yields and initial rate constants of product formation are shown to be concentration dependent. For the formation of carbonyl product 3 at lower starting material concentrations (N) and intermolecular H abstraction (k1) of methyl phenylglyoxylate (1d) are measured.
Synthesis of Chiral α-Aryl-α-Hydroxyacetic Acids: Substituent Effects in Pig Liver Acetone Powder (PLAP) Induced Enantioselective Hydrolysis
Basavaiah, Deevi,Krishna, Peddinti Rama
, p. 2403 - 2416 (2007/10/02)
Pig liver acetone powder (PLAP) catalyzed hydrolysis of alkyl α-acetoxy-α-arylacetates produces alkyl (S)-α-aryl-α-hydroxyacetates in 23-80percent enantiomeric purities.Enantioselectivity is dependent on the ester group of O-acetylmandelates.Substitution on the aromatic ring results in inferior selectivities.Only acetate group is hydrolyzed by PLAP while the ester functionality is found to be completely intact.
Synthesis of optically active alkynyl alcohols and α-hydroxy esters by microbial asymmetric hydrolysis of the corresponding acetates
Mori, Kenji,Akao, Hiroko
, p. 91 - 96 (2007/10/02)
Asymmetric hydrolysis of the acetates of racemic alkynyl alcohols and α-hydroxy esters by Bacillus subtilis var. Niger afforded optically active acetates and alcohols in 7-90% optical purities. The both enantiomers of optically pure mandelie acid were prepared by this microbial method.
