74384-21-7

Upstream product

• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 108-95-2 phenol 
• 104-01-8 4-Methoxyphenylacetic acid 
• 768-60-5 4-methoxyphenylacetylen 
• 15175-54-9 N,N-dimethyl-4-methoxylbenzylamine 
• 201230-82-2 carbon monoxide 
• 1416982-07-4 1-(4-methoxyphenyl)-N,N,N-trimethylmethanaminium trifluoromethanesulfonate 
• 31558-46-0 4-methoxybenzyl phenyl carbonate 
• 1885-14-9 phenyl chloroformate 
• 1439383-43-3 5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxane-4,6-dione 

Downstream Products

• 85274-97-1 2-(4-methoxyphenyl)-N-phenylacetamide 
• 79744-47-1 1-(2-hydroxyphenyl)-2-(4-methoxyphenyl)ethanone 
• 1459244-07-5 C₁₆H₁₃F₃O₅S 
• 71126-50-6 (3Z)-3-(4-methoxyphenylmethylidene)-2-benzofuran-1(3H)-one 
• 3669-47-4 1,2-Bis(4hydroxyphenyl)-ethanone 
• 3669-46-3 1-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethanone 
• 109561-92-4 1-(2-hydroxyphenyl)-2-(4-hydroxyphenyl)ethanone 

Relevant academic research and scientific papers

Palladium-Catalyzed Decarboxylative Carbonylative Transformation of Benzyl Aryl Carbonates: Direct Synthesis of Aryl 2-Arylacetates

A procedure on palladium-catalyzed decarboxylative alkoxycarbonylation of carbonates for the synthesis of aryl 2-arylacetates has been developed. A broad range of aryl 2-arylacetates were obtained in good yields under mild conditions under a carbon monoxide atmosphere. Interestingly, other alcohols can be added as nucleophiles as well, and the corresponding esters were also obtained in good yields.

Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters: Via C-N bond activation

An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C-N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.

Modular Synthesis of Arylacetic Acid Esters, Thioesters, and Amides from Aryl Ethers via Rh(II)-Catalyzed Diazo Arylation

One-pot formation of arylacetic acid esters, thioesters, and amides via Rh(II)-catalyzed arylation of a Meldrum's acid-derived diazo reagent with electron-rich arenes is described. The methodology was used to efficiently synthesize an anticancer compound.

Rhodium-catalyzed oxygenative addition to terminal alkynes for the synthesis of esters, amides, and carboxylic acids

A gem of a couple: The title reaction of terminal alkynes with O and Nnucleophiles proceeds in the presence of [Rh(cod)Cl}2], P(4-FC 6H4)3, and 4-picoline N-oxide. Alcohols, amines, and water add to the terminal alkynes to give esters, amides, and carboxylic acids, respectively. The reaction involves formation of a rhodium vinylidene, oxidation to a ketene by oxygen transfer, and nucleophilic addition.

Fries Rearrangement of ortho- and para-Methoxy Phenyl Acetates. The formation of Ketoesters

During the Fries rearrangement of o- and p-methoxy phenyl acetates with AlCl3 in nitromethane at 20 deg C substitution occurs mainly in the p-position of the phenolic residue to yield p-acylphenols.Larger quantities of o-acylphenols are obtained only, if