74384-21-7

Upstream product

• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 108-95-2 phenol 
• 104-01-8 4-Methoxyphenylacetic acid 
• 768-60-5 4-methoxyphenylacetylen 
• 1439383-43-3 5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 15175-54-9 N,N-dimethyl-4-methoxylbenzylamine 
• 201230-82-2 carbon monoxide 
• 1416982-07-4 1-(4-methoxyphenyl)-N,N,N-trimethylmethanaminium trifluoromethanesulfonate 
• 31558-46-0 4-methoxybenzyl phenyl carbonate 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 3669-47-4 1,2-Bis(4hydroxyphenyl)-ethanone 
• 3669-46-3 1-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethanone 
• 109561-92-4 1-(2-hydroxyphenyl)-2-(4-hydroxyphenyl)ethanone 
• 79744-47-1 1-(2-hydroxyphenyl)-2-(4-methoxyphenyl)ethanone 
• 71126-50-6 (3Z)-3-(4-methoxyphenylmethylidene)-2-benzofuran-1(3H)-one 
• 1459244-07-5 C₁₆H₁₃F₃O₅S 
• 85274-97-1 2-(4-methoxyphenyl)-N-phenylacetamide 

Relevant academic research and scientific papers

Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters: Via C-N bond activation

An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C-N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.

Palladium-Catalyzed Decarboxylative Carbonylative Transformation of Benzyl Aryl Carbonates: Direct Synthesis of Aryl 2-Arylacetates

A procedure on palladium-catalyzed decarboxylative alkoxycarbonylation of carbonates for the synthesis of aryl 2-arylacetates has been developed. A broad range of aryl 2-arylacetates were obtained in good yields under mild conditions under a carbon monoxide atmosphere. Interestingly, other alcohols can be added as nucleophiles as well, and the corresponding esters were also obtained in good yields.

Modular Synthesis of Arylacetic Acid Esters, Thioesters, and Amides from Aryl Ethers via Rh(II)-Catalyzed Diazo Arylation

One-pot formation of arylacetic acid esters, thioesters, and amides via Rh(II)-catalyzed arylation of a Meldrum's acid-derived diazo reagent with electron-rich arenes is described. The methodology was used to efficiently synthesize an anticancer compound.

Rhodium-catalyzed oxygenative addition to terminal alkynes for the synthesis of esters, amides, and carboxylic acids

A gem of a couple: The title reaction of terminal alkynes with O and Nnucleophiles proceeds in the presence of [Rh(cod)Cl}2], P(4-FC 6H4)3, and 4-picoline N-oxide. Alcohols, amines, and water add to the terminal alkynes to give esters, amides, and carboxylic acids, respectively. The reaction involves formation of a rhodium vinylidene, oxidation to a ketene by oxygen transfer, and nucleophilic addition.

Fries Rearrangement of ortho- and para-Methoxy Phenyl Acetates. The formation of Ketoesters

During the Fries rearrangement of o- and p-methoxy phenyl acetates with AlCl3 in nitromethane at 20 deg C substitution occurs mainly in the p-position of the phenolic residue to yield p-acylphenols.Larger quantities of o-acylphenols are obtained only, if