74444-81-8

Basic information

• Product Name: 5-Chloro-2-indanone
• Synonyms: 5-Chloro-2-indanone;5-Chloro-1H-inden-2(3H)-one;5-Chloro-indan-2-one;2H-Inden-2-one, 5-chloro-1,3-dihydro-
• CAS NO: 74444-81-8
• Molecular Formula: C₉H₇ClO
• Molecular Weight: 166.60428
• Mol File: 74444-81-8.mol

Chemical Properties

• Boiling Point: 284.2 °C at 760 mmHg
• Flash Point: 127.7 °C
• Appearance: /
• Density: 1.312 g/cm³
• Vapor Pressure: 0.00303mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Chloro-2-indanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-2-indanone(74444-81-8)
• EPA Substance Registry System: 5-Chloro-2-indanone(74444-81-8)

Safety Data

• Hazardous Substances Data: 74444-81-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Chloro-2-indanone is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Agrochemical Industry:
5-Chloro-2-indanone also serves as an intermediate in the production of agrochemicals, playing a role in the creation of substances that protect crops and enhance agricultural productivity.
Used in Organic Chemistry:
5-Chloro-2-indanone is utilized as a building block in the synthesis of other organic compounds, facilitating the construction of complex molecules for a range of applications in chemical research and industry.

InChI:InChI=1/C9H7ClO/c10-8-2-1-6-4-9(11)5-7(6)3-8/h1-3H,4-5H2

Upstream product

• 70090-69-6 1-chloro-4-(prop-2-yn-1-yl)benzene 
• 104-88-1 4-chlorobenzaldehyde 
• 4251-65-4 (4-chlorophenyl)acetaldehyde 
• 3970-52-3 6-chloro-1H-indene 
• 74444-80-7 Formic acid 5-chloro-1-hydroxy-indan-2-yl ester 

Downstream Products

• 1303607-07-9 (2'R,3S,3'S,5'R)-6-chloro-3'-(3-chloro-2-fluorophenyl)-5'-(2,2-dimethylpropyl)-N-(4-hydroxycyclohexyl)-2-oxospiro[1H-indole-3,4'-pyrrolidine]-2'-carboxamide 
• 897365-81-0 (3S,3'S,4'R,6'R,8'S,8a'R)-6-chloro-8'-(3-chloro-2-fluorophenyl)-6'-neopentyl-3',4'-diphenyl-3',4',8',8a'-tetrahydrospiro[indoline-3,7'-pyrrolo[2,1-c][1,4]oxazine]-1',2(6'H)-dione 
• 1303609-27-9 C₄₈H₅₈Cl₂FN₃O₄Si 
• 1303606-44-1 (2′R,3S,4′R,5′R)-6-chloro-4′-(3-chlorophenyl)-N-((1s,3S)-3-hydroxy-3-methylcyclobutyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide trifluoroacetic acid 
• 1303609-29-1 MI-519-65-TFA 
• 1303609-28-0 C₄₈H₅₈Cl₂FN₃O₄Si 
• 1303609-36-0 C₄₃H₄₆Cl₂FN₃O₄ 
• 1303609-37-1 (2'R,3S,4'S,5R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-N-(trans-4-hydroxycyclohexyl)-2'-neopentyl-2-oxospiro[indoline-3,3'-pyrrolidine]-5'-carboxamide trifluoroacetate 
• 897365-76-3 (3E/Z)-6-chloro-3-(3-chloro-2-fluorobenzylidene)-1,3-dihydro-2H-indol-2-one 
• 73536-83-1 5-chloro-2,3-dihydro-1H-inden-2-ylamine 
• 74444-76-1 acide amino-2 chloro-5 indane carboxylique-2 

Relevant articles and documents

Biarylphosphonite gold(I) complexes as superior catalysts for oxidative cyclization of propynyl arenes into indan-2-ones

Striking gold: A series of variously functionalized propynyl arenes was smoothly converted into indan-2-ones by a new gold(I)-catalyzed oxidative cyclization process. [LAu]NTf2 (Tf=trifluoromethanesulfonyl) is a superior catalyst both in terms of yield and kinetics for the present transformation. Copyright