7506-12-9

Usage

InChI:InChI=1/C15H11BrO3/c16-13-8-6-11(7-9-13)14(17)10-19-15(18)12-4-2-1-3-5-12/h1-9H,10H2

Upstream product

• 4203-30-9 1-(4-bromo-phenyl)-2-diazo-ethanone 
• 65-85-0 benzoic acid 
• 99-73-0 para-bromophenacyl bromide 
• 100-42-5 styrene 
• 99-90-1 para-bromoacetophenone 
• 5391-88-8 1-(4-bromophenyl)ethanol 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 586-75-4 4-chlorobenzoyl chloride 
• 582-25-2 Potassium benzoate 
• 532-32-1 sodium benzoate 

Downstream Products

• 23071-76-3 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-bromphenyl-)-propionitril 
• 99-90-1 para-bromoacetophenone 

Relevant academic research and scientific papers

Method for preparing alpha-acyloxy ketone compound

The invention discloses a method for preparing an alpha-acyloxy ketone compound. According to the invention, simple and easily available alcohol and carboxylic acid are taken as the raw materials, under mediation of NBS(N-bromo-succinimide) and DBU(1,8-diazabicyclo(5.4.0)undec-7-alkene), the alpha-acyloxy ketone is prepared by a one-pot reaction. The method has the advantages of mild reaction condition, simple and easily available raw materials, wide substrate adaptation scope, no requirement of rigorous reaction conditions such as any metal catalyst, peroxy compounds, low or high temperature and water-free and oxygen-free conditions, metal pollution is avoided; and the method also has the advantages of stable technical condition, simple and safe operation, and easy purifying of the product.

NBS/DBU mediated one-pot synthesis of α-acyloxyketones from benzylic secondary alcohols and carboxylic acids

A simple and efficient one-pot NBS/DBU-mediated method has been developed for the synthesis of α-acyloxyketones from various benzylic secondary alcohols and carboxylic acids. Through this methodology, a series of α-acyloxyketones could be obtained in good to excellent yields under mild conditions. Importantly, this new reaction avoids the direct usage of toxic metal catalysts or potentially dangerous peroxide oxidants.

NBu4NI-catalyzed α-benzoxylation of ketones with terminal aryl alkenes

A metal-free protocol for the α-benzoxylation of ketones has been developed by using terminal aryl alkenes as an arylcarboxy surrogate. Moderate to good yields were attained for a variety of propiophenones and acetophenones by using tetra-n-butylammonium iodide (TBAI) as the catalyst and tert-butyl hydroperoxide (TBHP) as the oxidant under ambient reaction conditions. An efficient synthesis for the α-benzoxylation of aryl ketones has been developed by using terminal aryl alkenes as the arylcarboxy surrogate. The products were obtained in moderate to good yields for a broad scope of substrates. Tetra-n-butylammonium iodide (TBAI) and tert-butyl hydroperoxide (TBHP) were employed as the catalyst and oxidant, respectively.

I2-catalyzed regioselective oxo- and hydroxy-acyloxylation of alkenes and enol ethers: A facile access to α-acyloxyketones, esters, and diol derivatives

I2-catalyzed oxo-acyloxylation of alkenes and enol ethers with carboxylic acids providing for the high yield synthesis of α-acyloxyketones and esters is described. This unprecedented regioselective oxidative process employs TBHP and Et3/s

Organic reactions in water: Synthesis of phenacyl esters from phenacyl bromide and potassium salts of aromatic acids in the presence of β-cyclodextrin

A convenient and facile synthesis of phenacyl esters is reported by the reaction of phenacyl bromide with potassium salts of aromatic acids in the presence of β-cyclodextrin in water under neutral conditions. Copyright Taylor & Francis, Inc.

Two acyl sucroses from Petunia nyctaginiflora

Two new acyl sucroses were isolated from the epigeal parts of Petunia nyctaginiflora Juss. (Solanaceae). Their structures were determined to be 2, 3, 4-tri (5- methylhexanoyl)-α-D-glucopyranosyl-β-D-fructofuranoside (2) and 2, 3, 4-tri (6-methylheptanoyl)

Efficient esterification of carboxylic acids with alkyl halides catalyzed by fluoride ions in ionic liquids

Ionic liquids based on 1,3-dialkylimidazolinium methanesulfonate have been used as efficient reusable reaction media in the esterification of several carboxylic acids with alkyl halides catalyzed by fluoride ions. The method has wide applicability, and it is mild and green; it is useful for the protection of acids, via ester formation, for alkali labile molecules.

TRIS(3,6-DIOXAHEPTYL)AMINE AS A PHASE-TRANSFER CATALYST IN PHENACYL ESTER SYNTHESIS

Tris(3,6-dioxaheptyl)amine (TDA-1) may be substituted for toxic crown ethers in the phase-transfer catalyzed synthesis of phenacyl esters from weakly nucleophilic potassium carboxylates and α,p-dibromoacetophenone in acetonitrile.

Kinetics of the Reactions of Phenacyl Bromide and of para-Substituted Phenacyl Bromides with Benzoate and Substituted trans-Cinnamate Ions

The second-order rate constants for the reactions of various para-substituted phenacyl bromides with benzoate ion and with several substituted trans-cinnamate ions have been measured in 90 percent acetone - 10 percent water (v/v) mixture.Electron-releasin

Separation of Polar and Steric Effects in Reactions of ortho-Substituted Benzoate Ions with para-Substituted Phenacyl Bromides

The second order rate constants for SN2 reactions of several ortho-substituted benzoate ions with several para-substituted phenacyl bromides have been measured in 90percent acetone - 10percent water (v/v) mixture at 35 deg C.Satisfactory correl