7510-33-0Relevant articles and documents
α-Diimine synthesis via titanium-mediated multicomponent diimination of alkynes with C-nitrosos
Cheng, Yukun,Egger, Dominic T.,Frye, Connor W.,Kounalis, Errikos,Pearce, Adam J.,Tonks, Ian A.
, p. 1469 - 1477 (2022/02/11)
α-Diimines are commonly used as supporting ligands for a variety of transition metal-catalyzed processes, most notably in α-olefin polymerization. They are also precursors to valuable synthetic targets, such as chiral 1,2-diamines. Their synthesis is usually performed through acid-catalyzed condensation of amines with α-diketones. Despite the simplicity of this approach, accessing unsymmetrical α-diimines is challenging. Herein, we report the Ti-mediated intermolecular diimination of alkynes to afford a variety of symmetrical and unsymmetrical α-diimines through the reaction of diazatitanacyclohexadiene intermediates with C-nitrosos. These diazatitanacycles can be readily accessed in situ via the multicomponent coupling of TiNR imidos with alkynes and nitriles. The formation of α-diimines is achieved through formal [4 + 2]-cycloaddition of the C-nitroso to the Ti and γ-carbon of the diazatitanacyclohexadiene followed by two subsequent cycloreversion steps to eliminate nitrile and afford the α-diimine and a Ti oxo.
White-Fluorescent Dual-Emission Mechanosensitive Membrane Probes that Function by Bending Rather than Twisting
Humeniuk, Heorhii V.,Rosspeintner, Arnulf,Licari, Giuseppe,Kilin, Vasyl,Bonacina, Luigi,Vauthey, Eric,Sakai, Naomi,Matile, Stefan
supporting information, p. 10559 - 10563 (2018/08/17)
Bent N,N′-diphenyl-dihydrodibenzo[a,c]phenazine amphiphiles are introduced as mechanosensitive membrane probes that operate by an unprecedented mechanism, namely, unbending in the excited state as opposed to the previously reported untwisting in the ground and twisting in the excited state. Their dual emission from bent or “closed” and planarized or “open” excited states is shown to discriminate between micelles in water and monomers in solid-ordered (So), liquid-disordered (Ld) and bulk membranes. The dual-emission spectra cover enough of the visible range to produce vesicles that emit white light with ratiometrically encoded information. Strategies to improve the bent mechanophores with expanded π systems and auxochromes are reported, and compatibility with imaging of membrane domains in giant unilamellar vesicles by two-photon excitation fluorescence (TPEF) microscopy is demonstrated.
A Highly Stereoselective Metal-Free Hydrogenation of Diimines for the Synthesis of Cis -Vicinal Diamines
Zhu, Xiaxia,Du, Haifeng
supporting information, p. 3106 - 3109 (2015/06/30)
A highly stereoselective metal-free hydrogenation of vicinal diimines has been successfully realized for the first time using 5-10 mol % of Piers borane as a catalyst under mild conditions, and a variety of cis-1,2-diamines were obtained in 92-99% yields.
In vitro bacteriostatic and DNA interaction studies of drug-based mixed-ligand complexes of cobalt(II)
Patel, Mohan,Chhasatia, Mehul,Bhatt, Bhupesh
experimental part, p. 220 - 230 (2012/03/10)
The dinuclear cobalt(II) complexes with ciprofloxacin and bidentate ligands were synthesized and characterized using infrared spectra, electronic spectra, magnetic measurements, elemental analyses, thermal investigation, and mass spectroscopy. Here in we
Antibacterial and DNA interaction studies of zinc(II) complexes with quinolone family member, ciprofloxacin
Patel, Mohan,Chhasatia, Mehul,Parmar, Pradhuman
experimental part, p. 439 - 446 (2010/04/02)
DNA binding and cleavage characteristics of Zn(II) complexes have been investigated. The DNA interaction property of the complexes has been investigated using absorption spectra, viscosity measurements, as well as gel electrophoresis studies. Intrinsic bi
Electronically tunable N-heterocyclic carbene ligands: 1,3-diaryl vs. 4,5-diaryl substitution
Ogle, James W.,Miller, Stephen A.
scheme or table, p. 5728 - 5730 (2010/01/31)
The catalytic activity of iridium-mediated transfer hydrogenation is readily tuned by electronic variation of the ligated tetraaryl-N-heterocyclic carbene and the installation of electron donating groups on the N-aryl substituents is more important than o
Synthesis of electronically diverse tetraarylimidazolylidene carbenes via catalytic aldimine coupling
Ogle, James W.,Zhang, Jubo,Reibenspies, Joseph H.,Abboud, Khalil A.,Miller, Stephen A.
supporting information; experimental part, p. 3677 - 3680 (2009/07/01)
(Chemical Equation Presented) A new method for synthesizing symmetrical N-heterocyclic imidazolium salts is described. Catalytic coupling of aldimines with cyanide followed by oxidation gives α-diketimines, which can then be cyclized with formaldehyde in
Microwave-assisted efficient synthesis of diimines in dry media using silica gel supported sodium hydrogen sulfate as reusable solid support
Bazgir, Ayoob
, p. 1 - 2 (2007/10/03)
A simple and efficient method for synthesis of diimines using silica gel supported sodium hydrogen sulfate as reusable solid support in solvent-free conditions under microwave irradiation is described.
A novel decyanogenative coupling of α-cyanoimines mediated by samarium. A facile route to α-diketimines
Thakur, Ashim J.,Prajapati, Dipak,Sandhu, Jagir S.
, p. 102 - 103 (2007/10/03)
Conversion of α-cyanoimines 1 into α-diketimines 2 has been achieved successfully by using samarium diiodide in dry tetrahydrofuran in high yields without formation of anilinoanil 3, 1,2-diamines 4 or anilides 5.
Formation of benzil diimines by microwave-assisted reaction of benzil with aromatic amines on alumina surface without solvent
Singh,Mahajan
, p. 410 - 411 (2007/10/03)
The microwave-assisted solvent-free reaction of benzil with aromatic amines (in 1 : 2 molar ratio) on an alumina surface for 4 min affords benzil diimines (1,2,3,4-tetraaryl-1,4-diaza-1,3-butadienes).