616-23-9

Basic information

• Product Name: 2,3-DICHLORO-1-PROPANOL
• Synonyms: alpha,beta-Dichlorohydrin Glycerol alpha,beta-Dichlorohydrin;2,3-DICHLORO-1-PROPANOL FOR SYNTHESIS;2,3-Dichloro-1-propanol >=97.0% (GC);1,2-Dichloro-3-propanol;1,2-Dichloropropanol-3;1-propanol,2,3-dichloro-;2,3-dichloro-1-propano;2,3-Dichloropropanol
• CAS NO: 616-23-9
• Molecular Formula: C₃H₆Cl₂O
• Molecular Weight: 128.99
• EINECS: 210-470-0
• Product Categories: Aliphatics;Mutagenesis Research Chemicals
• Mol File: 616-23-9.mol
• Article Data: 65

Chemical Properties

• Melting Point: -29.15°C
• Boiling Point: 182 °C
• Flash Point: 93 °C
• Appearance: Clear colorless/Liquid
• Density: 1.360 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.214mmHg at 25°C
• Refractive Index: 1.4835-1.4855
• Storage Temp.: Store below +30°C.
• Solubility: 1-10g/l
• PKA: 13.75±0.10(Predicted)
• BRN: 1732060
• CAS DataBase Reference: 2,3-DICHLORO-1-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DICHLORO-1-PROPANOL(616-23-9)
• EPA Substance Registry System: 2,3-DICHLORO-1-PROPANOL(616-23-9)

Safety Data

• Hazard Codes: T
• Statements: 20-24/25-41
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2810 6.1/PG 2
• WGK Germany: 3
• RTECS: UB1225000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 616-23-9(Hazardous Substances Data)

Usage

Chemical Properties

Different sources of media describe the Chemical Properties of 616-23-9 differently. You can refer to the following data:
1. CLEAR COLORLESS LIQUID
2. There are 4 isomers of dichloropropanols 1,3- dichloro-2-propanol (96-23-1) and “dichloropropanols” (26545-73-3) are citations in environmental regulations: C3H6OCl2 is a colorless viscous liquid with a chloroformlike odor. Slightly soluble in water. 1,3-Dichloro-2- propanol:

Uses

Different sources of media describe the Uses of 616-23-9 differently. You can refer to the following data:
1. An isomer of dichloropropanol; shows metabolite toxicity.
2. 2,3-Dichloro-1-propanol may be employed as carbon and energy supplement for the growth of Pseudomonas putida strain (MC4).

General Description

Viscous colorless to amber liquid with an ethereal odor.

Air & Water Reactions

May be sensitive to prolonged exposure to air. Slightly soluble in water.

Reactivity Profile

2,3-DICHLORO-1-PROPANOL is incompatible with oxidizers, oxygen and peroxides.

Fire Hazard

2,3-DICHLORO-1-PROPANOL is combustible.

Safety Profile

Poison by ingestion and skin contact. Moderately toxic by inhalation. A skin and severe eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORINATED HYDROCARBONS, AROMATIC.

Potential Exposure

It is used as a solvent for hard resins and nitrocellulose; in the manufacture of photographic chemicals and lacquer; as a cement for celluloid; and as a binder of water colors. It occurs in effluents from glycerol and halohydrin production plants.

Shipping

UN2750 1,3-Dichloropropanol-2, Hazard Class: 6.1; Labels: 6.1-Poisonous materials

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires orexplosions. Keep away from alkaline materials, strong acids, acid anhydrides, strong bases

InChI:InChI=1/C3H6Cl2O/c4-1-3(5)2-6/h3,6H,1-2H2/t3-/m0/s1

Upstream product

• 60-29-7 diethyl ether 
• 10140-89-3 2,3-dichloropropanal 
• 3761-92-0 n-hexylmagnesium bromide 
• 15454-33-8 chloromethanol 
• 75-01-4 chloroethylene 
• 107-18-6 allyl alcohol 
• 96-24-2 3-monochloro-1,2-propanediol 
• 56-81-5 glycerol 
• 78-92-2 iso-butanol 
• 127-65-1 chloroamine-T 
• 107-05-1 3-chloroprop-1-ene 
• 106-89-8 epichlorohydrin 
• 7647-01-0 hydrogenchloride 
• 7732-18-5 water 

Downstream Products

• 1126-00-7 1-phenylpyrazole 
• 62-53-3 aniline 
• 24910-84-7 2,3-dichloro-1-propyl acrylate 
• 51594-55-9 (R)-(-)-epichlorohydrin 
• 96-23-1 1,3-Dichloro-2-propanol 
• 96-18-4 1,2,3-trichloropropane 
• 96-24-2 3-chloro-1,2-propanediol 
• 616-23-9 2,3-dichloro-1-propanol 
• 616-23-9 (R)-2,3-Dichloro-1-propanol 
• 565-64-0 2,3-dichloropropanoic acid 
• 75-30-9 2-iodo-propane 
• 75-29-6 isopropyl chloride 
• 106-89-8 epichlorohydrin 
• 556-52-5 oxiranyl-methanol 

Relevant articles and documents

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Effect of sodium chloride on the solubility and hydrolysis of epichlorohydrin in water

The mutual solubility of the components in the epichlorhydrin–water–sodium chloride system was studied in the temperature range of 20–90 °С. It was found that epichlorohydrin is salted out as the concentration of NaCl increases. The Sechenov coefficient was determined to be equal to 0.29. It was found that epichlorohydrin reacts with an aqueous solution of sodium chloride to form glycerol dichlorohydrins. Alkali formed during this reaction catalyzes the hydrolysis of epichlorohydrin to glycerol monochlorohydrin, acts as a reagent in the glycidol formation and accelerates its subsequent conversion to glycerol.

Chlorohydrination of allyl chloride with HCl and H2O2 catalyzed by hollow titanium silicate zeolite to produce dichloropropanol

Overall, over 95% of epichlorohydrin is industrially manufactured via the chlorohydrination route with hazardous Cl2 as a reagent, which brings serious operation and pollution problems. Herein, we describe a novel Cl2-free process for the synthesis of dichloropropanols from allyl chloride with H2O2 and HCl catalyzed by hollow titanium silicate zeolite under mild conditions. A high conversion and overall dichloropropanol selectivity exceeding 95% are simultaneously achieved, and the heterogeneous catalyst is highly stable and amenable for reuse. Comprehensive experimental and spectroscopic data suggest that the Lewis acidity of the framework Ti species has a synergistic effect with the Br?nsted acidity of HCl that promotes the epoxidation of allyl chloride and the ring opening of the epoxy groups.

Method for comprehensive utilization of hexachloroethane

The invention relates to a comprehensive utilization method of a dichloroethane chlorination byproduct namely hexachloroethane. The comprehensive utilization method comprises the following steps: adding a hexachloroethane solution, glycerin, a hydrogenation catalyst and a chlorination catalyst into a high-pressure kettle; after feeding is finished, performing hydrodechlorination and glycerin chlorination reaction at the same time at certain temperature and under certain hydrogen pressure; after reaction is finished, maintaining the temperature for 4h, and then reducing the temperature to the room temperature; performing filtering separation to obtain the hydrogenation catalyst, layering reaction liquid to obtain a solvent layer and a glycerin layer, wherein the solvent layer contains a solvent, pentachloroethane, pentachloroethane and trichloroethane, and the glycerin layer contains the glycerin, dichloropropanol, water, the chlorination catalyst and monochlorohydrin.