77092-12-7

Basic information

• Product Name: 4H-1,3-Dioxin-4-one, 2,2-dimethyl-6-phenyl-
• Synonyms: 6-Ph-2,2-dimethyl-4H-1,3-dioxin-4-one;4H-1,3-Dioxin-4-one,2,2-dimethyl-6-phenyl;6-phenyl-2,2-dimethyl-1,3-dioxin-4-one;2,2-dimethyl-6-phenyl-2H,4H-1,3-dioxin-4-one;benzoylacetic acid;2,2-dimethyl-6-phenyl-4H-1,3-dioxin-4-one
• CAS NO: 77092-12-7
• Molecular Formula: C12H12O3
• Molecular Weight: 204.225
• Mol File: 77092-12-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4H-1,3-Dioxin-4-one, 2,2-dimethyl-6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Dioxin-4-one, 2,2-dimethyl-6-phenyl-(77092-12-7)
• EPA Substance Registry System: 4H-1,3-Dioxin-4-one, 2,2-dimethyl-6-phenyl-(77092-12-7)

Safety Data

• Hazardous Substances Data: 77092-12-7(Hazardous Substances Data)

Upstream product

• 67-64-1 acetone 
• 55991-67-8 5-phenylfuran-2,3-dione 
• 98-88-4 benzoyl chloride 
• 93139-50-5 3-phenylpropionic acid tert-butyl ester 
• 536-74-3 phenylacetylene 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 637-44-5 phenylpropyolic acid 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 54441-66-6 tert-butyl benzoylacetate 
• 65-85-0 benzoic acid 
• 73921-19-4 5-benzoyl-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 344757-82-0 tert-butyl 2-benzoylacetoacetate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 614-20-0 3-oxo-3-phenylpropionic acid 

Downstream Products

• 16054-92-5 N-(pyridin-2-yl)-3-oxo-3-phenylpropanamide 
• 120893-27-8 3-Oxo-3-phenyl-N-pyrimidin-2-yl-propionamide 
• 7733-48-4 N-acetylbenzoylacetamide 
• 84375-28-0 2-Dibutylamino-6-phenyl-[1,3]oxazin-4-one 
• 71645-35-7 6-phenyl-2-diethylamino-4H-1,3-oxazin-4-one 
• 140836-07-3 N-[1,2-Bis-[(E)-hydroxyimino]-2-(3-oxo-3-phenyl-propionylamino)-ethyl]-3-oxo-3-phenyl-propionamide 
• 93598-42-6 2-benzoyl-N-ethylcinnamamide 
• 93598-58-4 3-Ethyl-2,6-diphenyl-2,3-dihydro-[1,3]oxazin-4-one 
• 89046-92-4 2-(o-chloroanilino)-6-phenyl-1,3-oxazin-4-one 
• 126965-10-4 2-N-phenylguanidino-6-phenyl-1,3-oxazin-4-one 
• 124695-37-0 3-Benzoyl-4-oxo-6-phenyl-4H-pyran-2-carboxylic acid methyl ester 
• 124695-41-6 3-(4-Chloro-benzoyl)-4-oxo-6-phenyl-4H-pyran-2-carboxylic acid methyl ester 
• 90069-60-6 1,3-dibenzoyl-2-hydroxypyrrolo<2,1-a>isoquinoline 
• 93598-44-8 2-benzoyl-N-(2-pyridyl)cinnamamide 

Relevant articles and documents

Gold-catalyzed formal [4π+2π]-cycloadditions of tert-butyl propiolates with aldehydes and ketones to form 4H-1,3-dioxine derivatives

Gold-catalyzed formal hetero-[4π+2π] cycloadditions of tert-butyl propiolates with carbonyl compounds proceeded efficiently to yield 4H-1,3-dioxine derivatives over a wide scope of substrates. With acetone as a promoter, gold-catalyzed cycloadditions of these propiolate derivatives with enol ethers led to the formation of atypical [4+2]-cycloadducts with skeletal rearrangement.

Design and synthesis of epicocconone analogues with improved fluorescence properties

Epicocconone is a natural latent fluorophore that is widely used in biotechnology because of its large Stokes shift and lack of fluorescence in its unconjugated state. However, the low photostability and quantum yields of epicocconone have limited its wid

Flash flow pyrolysis: Mimicking flash vacuum pyrolysis in a high-temperature/high-pressure liquid-phase microreactor environment

Flash vacuum pyrolysis (FVP) is a gas-phase continuous-flow technique where a substrate is sublimed through a hot quartz tube under high vacuum at temperatures of 400-1100 °C. Thermal activation occurs mainly by molecule-wall collisions with contact times in the region of milliseconds. As a preparative method, FVP is used mainly to induce intramolecular high-temperature transformations leading to products that cannot easily be obtained by other methods. It is demonstrated herein that liquid-phase high-temperature/high- pressure (high-T/p) microreactor conditions (160-350 °C, 90-180 bar) employing near- or supercritical fluids as reaction media can mimic the results obtained using preparative gas-phase FVP protocols. The high-T/p liquid-phase "flash flow pyrolysis" (FFP) technique was applied to the thermolysis of Meldrum's acid derivatives, pyrrole-2,3-diones, and pyrrole-2-carboxylic esters, producing the expected target heterocycles in high yields with residence times between 10 s and 10 min. The exact control over flow rate (and thus residence time) using the liquid-phase FFP method allows a tuning of reaction selectivities not easily achievable using FVP. Since the solution-phase FFP method does not require the substrate to be volatile any more -a major limitation in classical FVP-the transformations become readily scalable, allowing higher productivities and space-time yields compared with gas-phase protocols. Differential scanning calorimetry measurements and extensive DFT calculations provided essential information on pyrolysis energy barriers and the involved reaction mechanisms. A correlation between computed activation energies and experimental gas-phase FVP (molecule-wall collisions) and liquid-phase FFP (molecule-molecule collisions) pyrolysis temperatures was derived.