77092-54-7

Upstream product

• 93-55-0 1-phenyl-propan-1-one 
• 19005-93-7 1H-indol-2-ylcarboxaldehyde 
• 40900-00-3 (1H-indol-2-yl)(phenyl)methanol 
• 1022-86-2 2-benzoylindole 
• 1530-32-1 ethyltriphenylphosphonium bromide 
• 100-58-3 phenylmagnesium bromide 
• 221044-05-9 N-(2-pyrimidyl)indole 
• 80814-95-5 diethyl (1-phenylprop-1-en-1-yl) phosphate 
• 39623-95-5 1-phenylprop-1-enyl acetate 
• 40899-71-6 1-benzenesulfonylindole 
• 77092-50-3 1-(1-Benzenesulfonyl-1H-indol-2-yl)-1-phenyl-propan-1-ol 

Downstream Products

• 106103-38-2 2-methyl-1-phenyl-9H-carbazole 
• 77092-51-4 3-Formyl-2-(1-phenyl-1-propenyl)indole 

Relevant academic research and scientific papers

C-H alkenylations with alkenyl acetates, phosphates, carbonates, and carbamates by cobalt catalysis at 23 °C

Inexpensive cobalt catalysts with N-heterocyclic carbene ligands enable direct arene alkenylations with easily accessible alkenyl acetates through regioselective C-H/C-O functionalizations in a stereoconvergent fashion. The versatile cobalt catalyst was b

Benzannulation of 2-Alkenylindoles using Aldehydes by Sequential Triple-Relay Catalysis: A Route to Carbazoles and Carbazole Alkaloids

Benzannulation of 2-alkenylindoles with readily available aldehydes, under one-pot sequential triple-relay-catalysis, provides an easy access to several structurally unique carbazoles including 2- and 3-alkenylcarbazoles. This protecting group-free method enabled one-pot synthesis of alkaloids such as hyellazole and 6-chlorohyellazole, and the formal syntheses of seven other alkaloids. Construction of the core structure, present in murastifoline A, murrafoline E, and related alkaloids was also demonstrated. Even conjugated 3,3′-biscarbazoles can also be synthesized by one-pot, two-fold sequential triple-relay catalysis. (Figure presented.).

Synthesis of Carbazole Alkaloids Hyellazole and 6-Chlorohyellazole

2-(1-Cyclohexenyl)-3-(β-methoxyvinyl)indole was heated in decalin in the presence of 5percent Pd-C to give 1,2,3,4-tetrahydro-5-methoxy-11H-benzocarbazole and 5-methoxy-11H-benzocarbazole. 3-(β-Methoxyvinyl)-2-(1-phenyl-1-propenyl)indole and 5-chloro-3-(β-methoxyvinyl)-2-(1-phenyl-1-propenyl)indole were also heated in decalin in the presence of 5percent Pd-C at 210 deg C, yielding the carbazole alkaloids hyellazole and 6-chlorohyellazole, respectively.

Synthesis of the Carbazole Alkaloid Hyellazole

Hyellazole, a new carbazole alkaloid, was synthesized via cyclisation of a 2,3-bis-vinylindole derivative.