77093-96-0

Usage

InChI:InChI=1/C10H9BrN2O2/c11-5-6-13-9(14)7-3-1-2-4-8(7)12-10(13)15/h1-4H,5-6H2,(H,12,15)

Upstream product

• 52727-44-3 2,3-dihydro-5H-oxazolo<2,3-b>quinazolin-5-one 
• 118-92-3 anthranilic acid 
• 5081-87-8 3-(2-chloroethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 118-48-9 isatoic anhydride 
• 77189-70-9 2-<3-(2-cloroethyl)ureido>benzonitrile 
• 13908-44-6 2-<3-(2-chloroethyl)ureido>benzoic acid 
• 1885-29-6 anthranilic acid nitrile 
• 134-20-3 2-carbomethoxyaniline 
• 77093-92-6 methyl 2-<3-(2-chloroethyl)ureido>benzoate 
• 77093-93-7 2-(2-chloroethylamino)-4H-<3,1>benzoxazin-4-one 
• 77093-94-8 2-(2-chloroethylamino)-4H-<3,1>benzoxazin-4-one hydrochloride 

Downstream Products

• 131729-02-7 1-[2-(2,4-Dioxo-1,4-dihydro-2H-quinazolin-3-yl)-ethyl]-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Nitrogenous heterocyclic compound with nematocidal activity, preparation method and application thereof

The invention relates to a nitrogenous heterocyclic compound with nematocidal activity, a preparation method and application thereof. Specifically, the invention discloses a compound with a formula (I) or an optical isomer, cis-trans isomer or acceptable salt in agricultural pharmacology and a preparation method thereof. The invention further discloses an agricultural composition containing the compound and application thereof. The compound has excellent nematocidal activity.

Reactions of o-Aminonitriles with Isocyanates. 1. A Two-Step Synthesis of 2,6-Dihydroimidazoquinazolin-5-(3H)one

The reaction of anthranilonitrile with 2-chloroethyl isocyanate yields 2-benzonitrile (6) which, upon heating, or treatment with base, undergoes a double cyclization to form 2,6-dihydroimidazoquinazolin-5-(3H)one (8) in excellent yield.When heated with hydrochloric acid, 6 is converted initially into 2-(2-chloroethylamino)-4H-benzoxazin-4-one (18) and further into 3-(2-chloroethyl)-2,4-(1H,3H)quinazolinedione (15).The acid-catalyzed reaction of 2,3-dihydro-5H-oxazoloquinazolin-5-one (14) with nucleophilic reagents yields 3-substituted 2,4-(1H,3H)quinazolinediones.