77093-99-3

Basic information

• Product Name: 3-(N-phenyl-2-aminoethyl)-2,4-(1H,3H)quinazolinedione
• CAS NO: 77093-99-3
• Molecular Weight: 281.314
• Mol File: 77093-99-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(N-phenyl-2-aminoethyl)-2,4-(1H,3H)quinazolinedione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N-phenyl-2-aminoethyl)-2,4-(1H,3H)quinazolinedione(77093-99-3)
• EPA Substance Registry System: 3-(N-phenyl-2-aminoethyl)-2,4-(1H,3H)quinazolinedione(77093-99-3)

Safety Data

• Hazardous Substances Data: 77093-99-3(Hazardous Substances Data)

Upstream product

• 13908-44-6 2-<3-(2-chloroethyl)ureido>benzoic acid 
• 1885-29-6 anthranilic acid nitrile 
• 5081-87-8 3-(2-chloroethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline 
• 118-92-3 anthranilic acid 
• 77093-93-7 2-(2-chloroethylamino)-4H-<3,1>benzoxazin-4-one 
• 77093-94-8 2-(2-chloroethylamino)-4H-<3,1>benzoxazin-4-one hydrochloride 
• 77189-70-9 2-<3-(2-cloroethyl)ureido>benzonitrile 
• 52727-44-3 2,3-dihydro-5H-oxazolo<2,3-b>quinazolin-5-one 
• 62-53-3 aniline 
• 134-20-3 2-carbomethoxyaniline 
• 77093-92-6 methyl 2-<3-(2-chloroethyl)ureido>benzoate 

Relevant articles and documents

Reactions of o-Aminonitriles with Isocyanates. 1. A Two-Step Synthesis of 2,6-Dihydroimidazoquinazolin-5-(3H)one

The reaction of anthranilonitrile with 2-chloroethyl isocyanate yields 2-benzonitrile (6) which, upon heating, or treatment with base, undergoes a double cyclization to form 2,6-dihydroimidazoquinazolin-5-(3H)one (8) in excellent yield.When heated with hydrochloric acid, 6 is converted initially into 2-(2-chloroethylamino)-4H-benzoxazin-4-one (18) and further into 3-(2-chloroethyl)-2,4-(1H,3H)quinazolinedione (15).The acid-catalyzed reaction of 2,3-dihydro-5H-oxazoloquinazolin-5-one (14) with nucleophilic reagents yields 3-substituted 2,4-(1H,3H)quinazolinediones.