7712-46-1

Basic information

• Product Name: 8-hydroxycarvotanacetone
• Synonyms: 8-hydroxycarvotanacetone;(4R)-4β-(1-Hydroxy-1-methylethyl)-1-methyl-1-cyclohexen-6-one;2-Cyclohexen-1-one, 5-(1-hydroxy-1-methylethyl)-2-methyl-;5-(1-Hydroxy-1-methylethel)-2-methyl-2-cyclohexen-1-one
• CAS NO: 7712-46-1
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 168.23284
• Mol File: 7712-46-1.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-hydroxycarvotanacetone(CAS DataBase Reference)
• NIST Chemistry Reference: 8-hydroxycarvotanacetone(7712-46-1)
• EPA Substance Registry System: 8-hydroxycarvotanacetone(7712-46-1)

Safety Data

• Hazardous Substances Data: 7712-46-1(Hazardous Substances Data)

Upstream product

• 56423-45-1 2-methyl-5-(1-methyl-1-oxiranyl)-2-cyclohexen-1-one 
• 98-55-5 terpineol 
• 32226-54-3 trans-sobrerol 
• 563-41-7 semicarbazide hydrochloride 
• 80-56-8 Pinene 
• 64-19-7 acetic acid 
• 13466-78-9 3-carene 
• 10482-56-1 (-)-(S)-α-terpineol 
• 67-64-1 acetone 
• 75-65-0 tert-butyl alcohol 
• 71-43-2 benzene 
• 80256-17-3 methyl 5,5-ethylenedioxy-4-methyl-3-dimethylphenylsilylcyclohexanecarboxylate 
• 2244-16-8 (S)-p-mentha-6,8-dien-2-one 
• 7785-70-8 (+)-α-pinene 

Downstream Products

• 99-49-0 Carvone 
• 499-75-2 carvacrol 
• 87578-93-6 (+/-) 4-(1'-acetoxymethylethyl)-1-methylcyclohex-1-en-6-one (8-acetoxyvotanacetone) 
• 2244-16-8 (S)-p-mentha-6,8-dien-2-one 
• 67-64-1 acetone 
• 116-51-8 terpenylic acid 
• 2437-97-0 (+/-)-4,7,7-trimethyl-6-oxabicyclo<3.2.1>oct-3-ene 
• 38235-58-4 trans-sobrerol 
• 454-77-3 1(S)-5(S)-(+)-cis-sobrerol 
• 58506-23-3 p-menthane-2,8-diol 
• 111323-96-7 C₁₇H₂₄N₂O₃S 

Relevant articles and documents

Microwave assisted bi-functional activation of β-bromo-tert-alcohols

Microwave-assisted dehydration-oxidation of β-bromo-tert-alcohols to afford 2,3-unsaturated ketones in good yield is reported. The reaction of substrates with DMSO in 1:1 ratio (w/v) is promoted by ZnS in a solvent-free condition. A concurrent bi-functional activation of trans-vicinal bromo- and hydroxyl groups with ZnS is elucidated. This is a new observation under microwave and applies to β-bromo-tert-alcohols derived from 1,4-disubstitued-1-cyclohexenes. It is very useful in the synthesis of 2,3-unsaturated ketones derived from monoterpenes which are valuable flavour compounds. [Figure not available: see fulltext.]

Formation of trans-verbenol and verbenone from α-pinene catalysed by immobilised Picea abies cells

Both enantiomers and the raceinate of α-pinene were transformed by Picea abies cells immobilised on alginate. The main products were cis- and trans-verbenol, the later being further transformed to verbenone. The enantiomeric purity of each product more or less corresponded to that of the substrate. Transformation by free cells was faster than that by the immobilised cells. The ratio of products differed to some extent between the transformation by tree and immobilised cells.

Palladium-catalyzed aerobic oxidative kinetic resolution of alcohols with an achiral exogenous base

Substitution of exogenous (-)-sparteine for a more practical achiral base in the aerobic oxidative kinetic resolution of secondary alcohols is described. Carbonate bases are the most effective of those screened and allow for effective kinetic resolution of benzylic, allylic, and aliphatic substrates. The procedure was also successfully extended to the oxidative desymmetrization of meso diols.