77469-29-5Relevant academic research and scientific papers
Fluoroalkanosulfonyl fluorides-mediated cyclodehydration of β-hydroxy sulfonamides and β-hydroxy thioamides to the corresponding aziridines and thiazolines
Yan, Zhaohua,Guan, Chengbo,Yu, Zhangxin,Tian, Weisheng
supporting information, p. 5788 - 5790 (2013/10/01)
An efficient method for the fluoroalkanosulfonyl fluoride-induced cyclodehydration of β-hydroxy sulfonamides and β-hydroxy thioamides to the corresponding aziridines and thiazolines is reported. Mild reaction conditions, operational simplicity, and high y
Chemistry and biology of diazonamide A: Second total synthesis and biological investigations
Nicolaou,Hao, Junliang,Reddy, Mali V.,Rao, Paraselli Bheema,Rassias, Gerasimos,Snyder, Scott A.,Huang, Xianhai,Chen, David Y.-K.,Brenzovich, William E.,Giuseppone, Nicolas,Giannakakou, Paraskevi,O'Brate, Aurora
, p. 12897 - 12906 (2007/10/03)
As an especially unique target for chemical synthesis, diazonamide A has the potential to be constructed through a plethora of synthetic routes, each attended by different challenges and opportunities for discovery. In this article, we detail our second total synthesis of diazonamide A through a sequence entirely distinct from that employed in our first campaign, one whose success required the development of several special strategies and tactics. We also disclose our complete studies regarding the chemical biology of diazonamide A and its structural congeners, and more fully delineate the scope of our protocol for Robinson-Gabriel cyclodehydration using pyridine-buffered POCl 3.
Research on radioprotective agents: Δ-2 Thiazolines and homologous derivatives
Robbe,Fernandez,Chapat,et al.
, p. 16 - 24 (2007/10/02)
Compounds derived from Δ-2 thiazoline, Δ-2 thiazolinium iodoalkylate and 4,5-dihydro-1,3 thiazine have been prepared and evaluated as potential antiradiation agents in mice. They generally have a low toxicity and significant radioprotective activity.
ETUDE COMPARATIVE DE LA PHOTOREACTIVITE D'ENAMIDES ET DE THIOENAMIDS AROMATIQUES TERTIAIRES
Couture, A.,Dubiez, R.,Lablanche-Combier, A.
, p. 1835 - 1844 (2007/10/02)
Photolytic reactions of some simple aromatic enamides and thioenamides illustrate a novel example of the dramatic difference in the photochemical behaviour of carbonyl and thiocarbonyl compounds.In contrast with their oxo-analogues which are photoconverted into enaminoketones, thioenamides undergo photochemical cyclization to yield isoquinolinethione derivatives which can be easily convered into isoquinolones and tetrahydroisoquinolines.
Thioenamide Photochemistry
Couture, Axel,Dubiez, Regine,Lablache-Combier, Alain
, p. 842 - 843 (2007/10/02)
In contrast with their oxo-analogues, thioenamides undergo photochemical cyclization to yield isoquinolinethione derivatives which are easily converted into isoquinolones and tetrahydroisoquinolines by treatment with benzeneseleninic anhydride and EtO3BF4
vic-Iodothiocyanates and Iodoisothiocyanates. Part 4. The Synthesis of 2-Substituted-2-thiazolines
Cambie, Richard C.,Chambers, David,Rutledge, Peter S.,Woodgate, Paul D.
, p. 40 - 51 (2007/10/02)
The reactions of trans-1-iodo-2-isothiocyanatocyclohexane with a number of carbon nucleophiles to form 2-substituted-2-thiazolines are described.Reactions of several vic-iodoisothiocyanates with butil-lithium give products which are dependent on the solvent and/or temperature.
