7790-92-3

Basic information

• Product Name: Hypochlorous acid
• Synonyms: hypochlorige Saeure;HClO;26190-92-1;Chlor(I)-saeure;hydroxidochlorine;[ClOH];HOCl;chloranol;14333-29-0
• CAS NO: 7790-92-3
• Molecular Formula: ClHO
• Molecular Weight: 52.46
• EINECS: 232-232-5
• Mol File: 7790-92-3.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 125-130 °C(Press: 11 Torr)
• Appearance: /
• Density: 1.1655 g/cm3
• PKA: 7.54±0.10(Predicted)
• CAS DataBase Reference: Hypochlorous acid(CAS DataBase Reference)
• NIST Chemistry Reference: Hypochlorous acid(7790-92-3)
• EPA Substance Registry System: Hypochlorous acid(7790-92-3)

Safety Data

• Hazardous Substances Data: 7790-92-3(Hazardous Substances Data)

Usage

General Description

Hypochlorous acid (HClO) is a weak acid that is derived from chlorine. It's an important compound used in sanitation, as it effectively kills bacteria, fungi, and viruses. As a disinfectant, it is commonly found in processes such as water treatment, wound treatment, and in some personal hygiene products. Despite its disinfecting properties, it is considered safe for humans and mammals. The acid is unstable alone, so it's often created in solutions with water. Its chemical structure allows it to penetrate harmful microorganisms and eliminate them quickly. However, it should be handled with care since it can cause irritation to the eyes and skin.

InChI:InChI=1S/ClHO/c1-2/h2H

Upstream product

• 7732-18-5 water 
• 7782-50-5 chlorine 
• 12653-71-3 mercury(II) oxide 
• 14545-72-3 chlorine nitrate 
• 10025-85-1 nitrogen trichloride 
• 624-85-1 ethyl hypochlorite 
• 7647-14-5 sodium chloride 
• 7298-89-7 2-chloro-5,5-dimethyl-1,3-cyclohexanedione 
• 7722-84-1 dihydrogen peroxide 
• 16887-00-6 chloride 
• 7647-01-0 hydrogenchloride 
• 7681-52-9 sodium hypochlorite 

Downstream Products

• 12190-75-9 chloroamine 
• 1542275-62-6 C₁₉H₃₄Cl₃F₃P₂Pt 
• 42009-92-7 1-chloro-1-hydroxymethylcyclohexane 
• 872289-69-5 2-chloro-6-methyl-cyclohexanol 

Relevant articles and documents

Melatonin prevents hypochlorous acid-mediated cyanocobalamin destruction and cyanogen chloride generation

Hypochlorous acid (HOCl) is a potent cytotoxic oxidant generated by the enzyme myeloperoxidase (MPO) in the presence of hydrogen peroxide (H2O2) and chloride (Cl?). Elevated levels of HOCl play an important role in various pathological conditions through oxidative modification of several biomolecules. Recently, we have highlighted the ability of HOCl to mediate the destruction of the metal-ion derivatives of tetrapyrrole macrocyclic rings such as hemoproteins and vitamin B12 (VB12) derivatives. Destruction of cyanocobalamin, a common pharmacological form of VB12 mediated by HOCl, results in the generation of toxic molecular products such as chlorinated derivatives, corrin ring cleavage products, the toxic blood agents cyanide (CN?) and cyanogen chloride (CNCl), and redox-active free cobalt. Here, we show that melatonin prevents HOCl-mediated cyanocobalamin destruction, using a combination of UV-Vis spectrophotometry, high-performance liquid chromatography analysis, and colorimetric CNCl assay. Identification of several melatonin oxidation products suggests that the protective role of melatonin against HOCl-mediated cyanocobalamin destruction and subsequent CNCl generation is at the expense of melatonin oxidation. Collectively, this work highlights that, in addition to acting as an antioxidant and as a MPO inhibitor, melatonin can also prevent VB12 deficiency in inflammatory conditions such as cardiovascular and neurodegenerative diseases, among many others.

Myeloperoxidase-mediated oxidation of edaravone produces an apparent non-toxic free radical metabolite and modulates hydrogen peroxide-mediated cytotoxicity in HL-60?cells

Edaravone is considered to be a potent antioxidant drug known to scavenge free radical species and prevent free radical-induced lipid peroxidation. In this study, we investigated the effect of edaravone on the myeloperoxidase (MPO) activity, an enzyme res

COMPOSITIONS OF HYPOCHLOROUS ACID(HOCl) AND METHODS OF MANUFACTURE THEREOF

The invention generally relates to compositions of hypochlorous acid (HOCl) and methods of manufacture thereof. In certain aspects, the invention provides air-free compositions of HOCl. In other aspects, the invention provides methods of making HOCl that involve mixing together in water in an air-free environment, a compound that generates a proton (H+) in water and a compound that generates a hypochlorite anion (OCl?) in water to thereby produce air-free hypochlorous acid.