78133-05-8Relevant academic research and scientific papers
Efficient Synthesis of Phosphonamidates through One-Pot Sequential Reactions of Phosphonites with Iodine and Amines
Chen, Xunwei,Luo, Wenjun,Wang, Yanlin,Li, Zikang,Ma, Xiaorui,Peng, Ai-Yun
, p. 14474 - 14480 (2020/10/06)
A one-pot sequential strategy to construct phosphonamidates has been developed by generating phosphonites in situ from arylmagnesium bromides and triethyl phosphite followed by treatment with iodine and amines. A variety of phosphonamidates were obtained with good to excellent yields at room temperature from easily available materials.
Ligand-free copper-catalyzed denitrogenative arylation of phosphorylamides with arylhydrazines
Zhu, Qiao,Che, Shiying,Luo, Zhenghong,Zhao, Zijian
, p. 947 - 957 (2020/02/27)
A straightforward arylation of phosphorylamides with arylhydrazines hydrochloride was herein demonstrated. The protocol proceeded in the presence of a catalytic loading of Cu(OAc)2 as the catalyst, DTBP as the external oxidant and Cs2CO3 as the base, but without any ligands. And a series of N-aryl phosphorylamides were successfully obtained in high efficiency (up to 93% yields) with good substituents compatibility (up to 30 examples). Free radical mechanism was proposed for the facile methodology based on the results of control reactions and literature explorations.
Rhodium-catalyzed oxidative coupling through C-H activation and annulation directed by phosphonamide and phosphinamide groups
Park, Sangjune,Seo, Boram,Shin, Seohyun,Son, Jeong-Yu,Lee, Phil Ho
supporting information, p. 8671 - 8673 (2013/09/23)
Rhodium-catalyzed oxidative coupling reactions via C-H activation and annulation directed by phosphonamide and phosphinamide groups were developed under aerobic conditions, which produced benzazaphosphole 1-oxides and phosphaisoquinolin-1-oxides.
Synthesis of phosphonamidate peptides by Staudinger reactions of silylated phosphinic acids and esters
Wilkening, Ina,Signore, Giuseppe Del,Hackenberger, Christian P. R.
, p. 349 - 351 (2011/03/17)
The Staudinger reaction of unprotected azido-peptides with silylated phosphinic acids and esters on the solid support offers a straightforward acid-free entry to different phosphonamidate peptide esters or acids under mild conditions in high purity and yield.
PHOTOLYTIC REARRANGEMENT OF PHOSPHORUS AZIDE : EVIDENCE FOR A TRANSIENT METAPHOSPHONIMIDATE.
Bertrand, Guy,Majoral, Jean-Pierre,Baceiredo, Antoine
, p. 5015 - 5018 (2007/10/02)
Photolysis of the oxide of diphenylphosphine azide gives rise to a transient metaphisphonimidate, a new tricoordinated pentavalent phosphorus compound.Evidence for this species was given by trapping reactions on a variety of substrates.
