78537-07-2Relevant academic research and scientific papers
Evidence of the Preferential Involvement of μ Receptors in Analgesia Using Enkephalins Highly Selective for Peripheral μ or δ Receptors
Gacel, Gilles,Fournie-Zaluski, Marie-Claude,Fellion, Etienne,Roques, Bernard P.
, p. 1119 - 1124 (2007/10/02)
In order to study the preferential involvement of μ or δ receptors in the analgesic effects of enkephalins, several peptides which selectively interact with these two kinds of receptors in peripheral organs were synthesized.The inhibitory potency on the e
Synthesis and pharmacological study of some enkephalin analogs in relation to the plurality of opiate receptors
Audigier,Mazarguil,Gout,Cros
, p. 173 - 177 (2007/10/02)
We have synthesized a series of enkephalin analogs and measured their affinity for each type of 'opiate' receptor, the μ receptor and the δ receptor. Furthermore, we have determined their respective antinociceptive activity after intracerebroventricular i
