79396-86-4

Upstream product

• 84969-57-3 Gly-Gly-Phe-Leu-NH₂*HCOOH 
• 10466-61-2 (2S)-amino-4-methylpentanamide hydrochloride 
• 126028-16-8 Boc-L-Tyr-Gly-Gly-L-Phe-OCam 
• 169676-30-6 Z-Gly-Gly-L-Phe-OCH₂CF₃ 
• 81638-86-0 (S)-2-((S)-2-amino-3-phenylpropanamido)-4-methylpentanamide hydrochloride 
• 13171-93-2 N-benzyloxycarbonyl-L-glycyl-L-glycyl-L-phenylalanine 
• 2130-96-3 O-benzyl-N-tert-butoxycarbonyl-L-tyrosine 
• 15027-03-9 Z-Gly-Gly-L-Phe-OMe 
• 81638-88-2 amide of N-t-butyloxycarbonyl-O-benzyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine 
• 84969-56-2 Z-Gly-Gly-L-Phe-L-Leu-NH₂ 
• 69472-91-9 tert-Butoxycarbonyl-O-benzyl-L-tyrosyl-glycyl-glycin 
• 82948-92-3 [des-tyr¹]-leucine enkephalinamide 

Downstream Products

• 79396-89-7 Tyr-Gly-Gly-Phe-Leu-NH₂*HCOOH 
• 79396-89-7 Tyr-Gly-Gly-Phe-Leu-NH₂*HCOOH 

Relevant academic research and scientific papers

α-chymotrypsin-catalysed segment condensations via the kinetically controlled approach using carbamoylmethyl esters as acyl donors in organic media

The superiority of the carbamoylmethyl ester as an acyl donor for the α-chymotrypsin-catalysed segment condensations via the kinetically controlled approach is demonstrated in several model systems carried out in organic media with low water content. Furthermore, this approach is successfully applied to the construction of the Leu-enkephalin sequence via a 4 + 1 segment coupling.

Superiority of the carbamoylmethyl ester as an acyl donor for the protease-catalyzed kinetically controlled peptide synthesis in organic media: Application to segment condensations

The superiority of the carbamoylmethyl ester as an acyl donor for the α-chymotrypsin-catalyzed kinetically controlled peptide synthesis was demonstrated in several segment condensations carried out in organic media with low water content. Then this approach was successfully applied to the construction of the Leuenkephalin sequence via the 4 + 1 segment condensation.

Catalytic Transfer Hydrogenation in Pepetide Synthesis: Synthesis of 5- and 5-enkephalins

The simplicity in the removal of N-protecting groups like benzyloxycarbonyl employed in peptide synthesis by catalytic transfer hydrogenation at room temperature using formic acid in presence of palladium black has been demonstrated by the synthesis of the opioid pentapeptides 5- and 5-enkephalins.