80058-85-1Relevant articles and documents
A practical and improved copper-catalyzed synthesis of the central intermediate of diafenthiuron and related products
Schareina, Thomas,Zapf, Alexander,Cotte, Alain,Mueller, Nikolaus,Beller, Matthias
, p. 537 - 539 (2008)
A bioinspired Cu(I)/N-methylimidazole catalyst system is used for the synthesis of the diaryl ether part of diafenthiuron, a widely used insecticide. The convenient protocol proceeds smoothly with high selectivity and quantitative yield. Applying the optimized procedure various diaryl ether analogs are synthesized in good to excellent yield.
Synthesis method of diafenthiuron impurity D
-
Paragraph 0023; 0036-0040, (2021/08/06)
The invention provides a preparation method of the diafenthiuron impurity D. According to the preparation method of the diafenthiuron impurity D, 2, 6-isopropylaniline, phenol, CS2 and the like are used as raw materials, a material basis is provided for regularly researching the impurities, and the method can also be used for qualitative and quantitative analysis of the impurities in diafenthiuron production. And the impurities are controlled within a safe and reasonable limit range, so that the quality standard of the diafenthiuron can be improved, and important guiding significance is provided for safe medication of the masses.
PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS
-
Page/Page column 3; 5, (2009/06/27)
Described is a process for preparing diaryl ethers of the formula (I) [in-line-formulae]Ar—O—Ar′??(I)[/in-line-formulae]In which Ar is an aryl or substituted aryl group and Ar′ is an aryl, substituted aryl, heteroaryl or substituted heteroaryl group,by reacting an aryl of formula (II) or a aryloxy salt of formula (III) [in-line-formulae]Ar—OH ??(II)[/in-line-formulae] [in-line-formulae]Ar—OR ??(III)[/in-line-formulae]In which Ar has the same meaning as in formula (I) and R is an alkali metal,with an aryl or heteroaryl bromide of formula (IV) [in-line-formulae]Ar′—Br ??(IV)[/in-line-formulae]In which Ar′ has the same meaning as in formula (I),characterized in that the reaction is carried out in the presence of a copper(I)salt and a 1-substituted imidazole as catalyst system.