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4-(Methoxymethyl)aniline, a derivative of aniline, is a chemical compound with the structural formula C9H13NO and a molar mass of 151.21 g·mol-1. It is part of the aniline family, which is extensively used in the production of dyes. 4-(METHOXYMETHYL)ANILINE is typically presented as a colorless or slightly yellow liquid and possesses toxicological properties, making it potentially harmful if ingested, inhaled, or comes into contact with skin. As a result, protective clothing is necessary when handling this chemical, and it should be stored in a cool, dry, well-ventilated area away from incompatible materials. Its usage and disposal must adhere to local environmental regulations.

80936-82-9

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80936-82-9 Usage

Uses

Used in Chemical Industry:
4-(Methoxymethyl)aniline is used as a chemical intermediate for the synthesis of various materials, particularly in the production of dyes. Its presence in the aniline family makes it a valuable component in the creation of a wide range of colorants.
Used in Pharmaceutical Industry:
4-(Methoxymethyl)aniline is used as a building block in the development of pharmaceutical compounds, contributing to the synthesis of various drugs and medications.
Used in Research and Development:
4-(METHOXYMETHYL)ANILINE is utilized in research settings to study its properties and potential applications, including its reactivity, stability, and interactions with other chemicals.
Used in Environmental Management:
4-(Methoxymethyl)aniline is used in the development of strategies for its safe handling, storage, and disposal, ensuring compliance with local environmental regulations and minimizing its potential impact on the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 80936-82-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,9,3 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 80936-82:
(7*8)+(6*0)+(5*9)+(4*3)+(3*6)+(2*8)+(1*2)=149
149 % 10 = 9
So 80936-82-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO/c1-10-6-7-2-4-8(9)5-3-7/h2-5H,6,9H2,1H3

80936-82-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(Methoxymethyl)aniline

1.2 Other means of identification

Product number -
Other names 4-(METHOXYMETHYL)ANILINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:80936-82-9 SDS

80936-82-9Relevant academic research and scientific papers

Total Syntheses of the Amaryllidaceae Alkaloids Zephycandidine III and Lycosinine A and Their Evaluation as Inhibitors of Acetylcholinesterase

Xu, Xingjun,Kim, Hye-Sun,Chen, Wei-Min,Ma, Xiang,Correy, Galen J.,Banwell, Martin G.,Jackson, Colin J.,Willis, Anthony C.,Carr, Paul D.

, p. 4044 - 4053 (2017/07/28)

The title alkaloids, 1 and 2, have been prepared using cross-coupling chemistries and together with various analogues they have been evaluated for their capacity to inhibit acetylcholinesterase. Contrary to an earlier report, it was found that biaryl 1 is not a significant inhibitor of this enzyme, and neither are any of its congeners, including alkaloid 2.

Chemoselective hydrogenation of nitrobenzyl ethers to aminobenzyl ethers catalyzed by palladium-nickel bimetallic nanoparticles

Chen, Wenwen,Bao, Hailin,Wang, Dingsheng,Wang, Xinyan,Li, Yadong,Hu, Yuefei

, p. 9240 - 9244 (2015/11/27)

A highly efficient and chemoselective hydrogenation of nitrobenzyl ethers to aminobenzyl ethers was developed by using a novel palladium-nickel bimetallic nanocatalyst. Since the catalytic selectivity was resulted from the synergistic effects between two metals rather than the traditional catalyst poisons, the hydrogenation proceeded smoothly under additive-free conditions. Thus, the work-up procedure was as simple as to recover the catalyst by a magnetic separation and then to evaporate the solvent.

OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS

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Page/Page column 159; 160, (2015/05/19)

This invention pertains generally to treating bacterial infections using organic compounds of Formula I. In certain aspects, the invention pertains to treating infections caused by Gram-negative bacteria. (I) wherein X, Y, R1, R2, R3, R4 and R5 and defined herein.

Fluorescent perylene diimide rotaxanes: Spectroscopic signatures of wheel-chromophore interactions

Baggerman, Jacob,Jagesar, Dhiredj C.,Vallee, Renaud A. L.,Hofkens, Johan,De Schryver, Frans C.,Schelhase, Franke,Voegtle, Fritz,Brouwer, Albert M.

, p. 1291 - 1299 (2007/10/03)

[2]- and [3]-rotaxanes with a tetraphenoxy perylene diimide core were synthesized. Hydrogen bonding between the wheel and the imide changes the optical properties of the perylene chromophore: the absorption and fluorescence spectra are red-shifted. The decay times of the rotaxanes are shorter in comparison with that of the axle. Single molecule fluorescence measurements reveal relatively narrow distributions of emission maxima and decay times. The averages are in agreement with ensemble measurements. The observed red shifts make the perylene diimide a suitable chromophore for sensing the position of the wheel on the axle.

IMIDAZOQUINOLINES AS LIPID KINASE INHIBITORS

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Page/Page column 59, (2008/06/13)

The invention relates to novel organic compounds of formula (I) processes for the preparation thereof, the application thereof in a process for the treatment of the human or animal body, the use thereof - alone or in combination with one or more other pharmaceutically active compounds - for the treatment of an inflammatory or obstructive airway disease, such as asthma, disorders commonly occurring in connection with transplantation, or a proliferative disease, such as a tumor disease.

Indium metal as a reducing agent in organic synthesis

Pitts,Harrison,Moody

, p. 955 - 977 (2007/10/03)

The low first ionisation potential (5.8 eV) of indium coupled with its stability towards air and water, suggest that this metallic element should be a useful reducing agent for organic substrates. The use of indium metal for the reduction of C=N bonds in imines, the heterocyclic ring in benzo-fused nitrogen heterocycles, of oximes, nitro compounds and conjugated alkenes and the removal of 4-nitrobenzyl protecting groups is described. Thus the heterocyclic ring in quinolines, isoquinolines and quinoxalines is selectively reduced using indium metal in aqueous ethanolic ammonium chloride. Treatment of a range of aromatic nitro compounds under similar conditions results in selective reduction of the nitro groups; ester, nitrile, amide and halide substituents are unaffected. Likewise indium in aqueous ethanolic ammonium chloride is an effective method for the deprotection of 4-nitrobenzyl ethers and esters. Indium is also an effective reducing agent under non-aqueous conditions and α-oximino carbonyl compounds can be selectively reduced to the corresponding N-protected amine with indium powder, acetic acid in THF in the presence of acetic anhydride or di-tert-butyl dicarbonate. Conjugated alkenes are also reduced by indium in THF-acetic acid.

Indium as a reducing agent: Reduction of aromatic nitro groups

Moody, Christopher J.,Pitts, Michael R.

, p. 1028 - 1028 (2007/10/03)

Treatment of a range of aromatic nitro compounds with indium powder in aqueous ethanolic ammonium chloride results in selective reduction of the nitro groups; ester, nitrile, amide and halide substituents are unaffected.

Different Patterns of Mutagenicity of Arenediazonium Ions in V79 Cells and Salmonella typhimurium TA102: Evidence for Different Mechanisms of Action

Lawson, Terence,Gannett, Peter M.,Yau, Wai-Ming,Dalal, Nar S.,Toth, Bela

, p. 2627 - 2635 (2007/10/03)

The edible mushroom Agaricus bisporus contains several arylhydrazines and arenediazonium ions that are genotoxins.The mechanism whereby arylhydrazines and arenediazonium ions are genotoxic is unknown and may be due to the arenediazonium ion itself or to a

Oxidation of Aromatic Compounds. I. Oxidation of Methyl Derivatives of Nitrobenzene and Aniline in the System HSO3F-PbO2

Rudenko, A. P.,Korovina, N. S.,Aver'yanov, S. F.

, p. 1077 - 1083 (2007/10/03)

Low-temperature oxidation of methyl derivatives of nitrobenzene and aniline in the system HSO3F-PbO2 proceeds with intermediate formation of radical cations and results in replacement of hydrogen in one or two methyl groups or yields compounds of the diphenylmethane and biphenyl series.

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