81131-40-0

Basic information

• Product Name: Cyclohexanecarboxylic acid, 3-amino-, (1S-cis)- (9CI)
• Synonyms: Cyclohexanecarboxylic acid, 3-amino-, (1S-cis)- (9CI);(1S,3R) -3-AMINO-CYCLOHEXANECARBOXYLIC ACID;(1S, 3R)- 3-AMINO-CYCLOHEXANOIC ACID;(1S,3R)-3-Aminocyclohexanecarboxylic Acid;(1S,3R)-3-AMINOCYCLOHEXANECARBOXYLIC ACID (WX191419);(1S,3R)-3-aminocyclohexane-1-carboxylic acid
• CAS NO: 81131-40-0
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.18362
• Product Categories: AMINOACID
• Mol File: 81131-40-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 240°C(lit.)
• Boiling Point: 280.0±33.0 °C(Predicted)
• Appearance: /
• Density: 1.133±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.99±0.10(Predicted)
• CAS DataBase Reference: Cyclohexanecarboxylic acid, 3-amino-, (1S-cis)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 3-amino-, (1S-cis)- (9CI)(81131-40-0)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 3-amino-, (1S-cis)- (9CI)(81131-40-0)

Safety Data

• Hazardous Substances Data: 81131-40-0(Hazardous Substances Data)

Usage

General Description

Cyclohexanecarboxylic acid, 3-amino-, (1S-cis)- (9CI) is a chemical compound with the molecular formula C7H13NO2. It is a derivative of cyclohexanecarboxylic acid, which is a white crystalline solid with a faint odor. The compound is primarily used in the pharmaceutical industry as a chiral building block for the synthesis of various drugs and pharmaceutical intermediates. It has also been studied for its potential therapeutic applications in the treatment of neurological and psychiatric disorders. Additionally, this compound has shown promise in the development of novel materials and as a reagent in organic synthesis.

Upstream product

• 123-51-3 i-Amyl alcohol 
• 99-05-8 meta-aminobenzoic acid 
• 334932-13-7 3-[(tert-butoxycarbonyl)amino]cyclo-hexanecarboxylic acid 
• 81131-38-6 (1S,3R)-3-phthalimidocyclohexanecarboxylic acid 
• 4720-83-6 6-oxabicyclo[3.2.1]oct-3-en-7-one 
• 116724-13-1 trans rac-cyclohexyl 1,3-dicarboxylic acid 
• 81201-62-9 (d,l)-cis-3-phthalimidocyclohex-4-ene-1-carboxylic acid 
• 81202-30-4 (1S,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-cyclohex-3-enecarboxylic acid 
• 81086-73-9 ethyl cis-5-phthalimidocyclohex-3-ene-1-carboxylate 
• 81086-72-8 5-Bromo-cyclohex-3-enecarboxylic acid ethyl ester 
• 15111-56-5 ethyl-3-cyclohexene-1-carboxylate 

Downstream Products

• 194471-84-6 (1R,3R)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-cyclohexanecarboxylic acid 
• 194471-84-6 (1S,3R)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-cyclohexanecarboxylic acid 
• 925921-14-8 3-hydroxymethyl-1-cyclohexylamine 
• 87091-29-0 methyl 3-aminocyclohexanecarboxylate 
• 202120-10-3 (1S,3R)-3-aminocyclohexylcarboxylic acid methyl ester 
• 1070166-06-1 4-(3-carboxycyclohexylamino)-2-chloro-7H-pyrrolo[2,3-d]pyrimidine 
• 1142087-64-6 3-{[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]amino}cyclohexanecarboxylic acid 
• 53084-60-9 ethyl 3-aminocyclohexanecarboxylate 

Relevant articles and documents

An improved synthesis of (1R,3S)-3-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid

An improved synthesis of (1R,3S)-3-[(tert-butoxycarbonyl)amino] cyclohexanecarboxylic acid from 3-aminobenzoic acid is described utilising milder and more selective conditions. Both a classical salt resolution and an enzymatic approach have been shown to give the desired compound in high selectivity.

Substituted pyrroles suitable for continuous infusion

Disclosed are novel substituted pyrroles having the formula These compounds and their pharmaceutically acceptable salts are suitable for administration to patients as continuous infusion solution and are useful in the treatment and/or control of cell prol

2-aminopyridine derivatives and combinatorial libraries thereof

The present invention relates to novel 2-aminopyridine derivative compounds of the following formula: wherein R1to R5have the meanings provided herein. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing 2-aminopyridine derivative compounds.