81518-74-3

Basic information

• Product Name: Benzene, [(4-pentenyloxy)methyl]-
• CAS NO: 81518-74-3
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• Mol File: 81518-74-3.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: Benzene, [(4-pentenyloxy)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(4-pentenyloxy)methyl]-(81518-74-3)
• EPA Substance Registry System: Benzene, [(4-pentenyloxy)methyl]-(81518-74-3)

Safety Data

• Hazardous Substances Data: 81518-74-3(Hazardous Substances Data)

Upstream product

• 821-09-0 n-Pent-4-enyl alcohol 
• 100-52-7 benzaldehyde 
• 1119-51-3 bromopentene 
• 100-51-6 benzyl alcohol 
• 154732-05-5 3-(benzyloxy)propyl trifluoromethanesulfonate 
• 1826-67-1 vinyl magnesium bromide 
• 4799-68-2 3-benzyloxypropan-1-ol 
• 5470-84-8 4-benzyloxybutanal 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 4541-14-4 4-benzyloxy-butan-1-ol 
• 57618-47-0 5-benzyloxy-1-pentyne 
• 133625-41-9 4-benzyloxybutyraldehyde dimethyl acetal 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 65539-72-2 2-(phenylselanylmethyl)oxolane 
• 258331-45-2 Acetic acid (E)-8-benzyloxy-3-methylene-oct-4-enyl ester 
• 83458-88-2 (+/-)-5-benzyloxy-1,2-pentanediol 
• 1277181-01-7 diethyl 2-(6-(benzyloxy)-2-bromohexyl)malonate 
• 98689-66-8 (Z)-pent-3-en-1-yloxymethylbenzene 
• 3528-12-9 1,4-bis(trimethylsilyl)2-butene 
• 150760-92-2 3-(3-benzyloxy-propyl)-<1.2.4>-trioxolane 
• 112482-35-6 1-(benzyloxy)-4,5-epoxypentane 
• 5470-84-8 4-benzyloxybutanal 
• 4541-14-4 4-benzyloxy-butan-1-ol 

Relevant articles and documents

Synthesis and evaluation of novel, selective, functionalized γ-butyrolactones as sigma-2 ligands

The sigma-2 (σ2) receptor was discovered nearly 40 years ago and was recently identified as the Transmembrane Protein 97 (TMEM97, also known as MAC30 (Meningioma-associated protein)). Aberrant σ2 activity has been linked to diseases

Enabling the Use of Alkyl Thianthrenium Salts in Cross-Coupling Reactions by Copper Catalysis

Alkyl groups are one of the most widely used groups in organic synthesis. Here, a a series of thianthrenium salts have been synthesized that act as reliable alkylation reagents and readily engage in copper-catalyzed Sonogashira reactions to build C(sp3)?C(sp) bonds under mild photochemical conditions. Diverse alkyl thianthrenium salts, including methyl and disubstituted thianthrenium salts, are employed with great functional breadth, since sensitive Cl, Br, and I atoms, which are poorly tolerated in conventional approaches, are compatible. The generality of the developed alkyl reagents has also been demonstrated in copper-catalyzed Kumada reactions.

Thioether-Directed NiH-Catalyzed Remote γ-C(sp3)-H Hydroamidation of Alkenes by 1,4,2-Dioxazol-5-ones

A NiH-catalyzed thioether-directed cyclometalation strategy is developed to enable remote methylene C-H bond amidation of unactivated alkenes. Due to the preference for five-membered nickelacycle formation, the chain-walking isomerization initiated by the NiH insertion to an alkene can be terminated at the γ-methylene site remote from the alkene moiety. By employing 2,9-dibutyl-1,10-phenanthroline as the ligand and dioxazolones as the reagent, the amidation occurs at the γ-C(sp3)-H bonds to afford the amide products in up to 90% yield (>40 examples) with remarkable regioselectivity (up to 24:1 rr).