81581-40-0Relevant academic research and scientific papers
Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase
Van Linden, Oscar P.J.,Farenc, Carine,Zoutman, Willem H.,Hameetman, Liesbeth,Wijtmans, Maikel,Leurs, Rob,Tensen, Cornelis P.,Siegal, Gregg,De Esch, Iwan J.P.
supporting information; experimental part, p. 493 - 500 (2012/03/11)
The in silico identification, optimization and crystallographic characterization of a 6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c]isoquinolin-1-amine scaffold as an inhibitor for the EPHA4 receptor tyrosine kinase is described. A database containing commercially
Studies on fused 2(1H)-pyridenethiones: New routes for the synthesis of fused 1H-pyrazolo[3,4-b]pyridines and fused thieno[2,3-b]pyridines
Al-Kaabi, Sharifa Soltan,Elgemeie, Galal Eldin Hamza
, p. 2241 - 2245 (2017/03/31)
A synthesis of fused 1H-pyrazolo[3,4-b]pyridines and fused thieno[2,3-b]pyridines utilizing fused 2(1H)-pyridinethiones as starting components is described. The structures of the products were assigned and confirmed on the basis of their elemental analysi
Studies on Fused 2(1H)-Pyridenethiones: New Routes for the Synthesis of Fused 1H-Pyrazolopyridines and Fused Thienopyridines
Al-Kaabi, Sharifa Soltan,Elgemeie, Galal Eldin Hamza
, p. 2241 - 2245 (2007/10/02)
A synthesis of fused 1H-pyrazolopyridines and fused thienopyridines utilizing fused 2(1H)-pyridinethiones as starting components is described.The structures of the products were assigned and confirmed on the basis of their elemental analysis
Amide-Catalysed Isomerisation of 5,6-Dihydroisoquinolines: a Novel Synthesis of 1,2-Dihydroisoquinolines
Kasturi, Tirumalai Rangachar,Krishnan, Lalitha,Prasad, Ramanujam Srinivasa
, p. 63 - 68 (2007/10/02)
Knoevenagel condensation of 2-acylcyclohexanones or 2-ethoxycarbonylcyclohexanone with either cyanoacetamide or malononitrile followed by silver salt alkylation gave the 5,6,7,8-tetrahydroisoquinolines (3a-i).Chromic acid oxidation of the 5,6,7,8-tetrahyd
