81968-57-2

Upstream product

• 64030-44-0 (2S)-2-(anilinomethyl)pyrrolidine 
• 6630-33-7 ortho-bromobenzaldehyde 
• 64030-42-8 benzyl (2S)-2-(phenylcarbamoyl)pyrrolidine-1-carboxylate 
• 147-85-3 L-proline 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 25746-83-2 (2S)-N-phenylpyrrolidine-2-carboxamide 

Downstream Products

• 131035-30-8 Acetic acid (S)-1-(2-acetoxymethyl-phenyl)-pentyl ester 
• 137333-69-8 (S)-1-<2-(hydroxymethyl)phenyl>propanol 
• 137333-71-2 (S)-1-<2-(hydroxymethyl)phenyl>pentanol 
• 131035-32-0 Acetic acid (S)-1-(2-acetoxymethyl-phenyl)-2-methyl-propyl ester 
• 99291-16-4 (S)-1-(2-Hydroxymethyl-phenyl)-2-methyl-propan-1-ol 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS BASED ON CHIRAL DIAMINES HAVING PYRROLIDINE RING

Various highly stereoselective asymmetric reactions based on chiral diamines having pyrrolidine ring are described.Some of these reactions have been successfully applied to the syntheses of natural products.

ENANTIOFACE-DIFFERENTIATING ADDITION OF A CHIRAL ARYLLITHIUM REAGENT TO ALDEHYDES

A chiral aryllithium reagent was prepared by treating a chiral aminal, derived from (S)-2-(anilinomethyl)pyrrolidine and o-bromobenzaldehyde, with n-butyl lithium.The chiral reagent reacted highly enantioface selectively with aliphatic aldehydes and, on h