82902-54-3

Basic information

• Product Name: phenyl(4-phenylpiperidin-1-yl)methanone
• Synonyms: phenyl(4-phenylpiperidin-1-yl)methanone
• CAS NO: 82902-54-3
• Molecular Weight: 265.355
• Mol File: 82902-54-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: phenyl(4-phenylpiperidin-1-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl(4-phenylpiperidin-1-yl)methanone(82902-54-3)
• EPA Substance Registry System: phenyl(4-phenylpiperidin-1-yl)methanone(82902-54-3)

Safety Data

• Hazardous Substances Data: 82902-54-3(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 100-59-4 phenylmagnesium chloride 
• 98-88-4 benzoyl chloride 
• 107264-22-2 C₂₆H₂₄N₂O₃ 
• 71-43-2 benzene 
• 771-99-3 4-phenylpiperidine 
• 93-89-0 benzoic acid ethyl ester 
• 611-73-4 Benzoylformic acid 
• 1078-58-6 diphenylzinc 
• 19015-37-3 1-(phenylmethyl)-4-phenylpiperidine 
• 100-52-7 benzaldehyde 
• 115755-50-5 1-benzoyl-4-piperidinecarbonyl chloride 
• 5274-99-7 1-benzoylisonipecotic acid 

Relevant articles and documents

Catalytic N-Acylation of Cyclic Amines by Arylglyoxylic Acids via Radical-Radical Cross-Coupling

A methodical mechanistic investigation allowed for the catalytic N-acylation of secondary cyclic amine counterparts by arylglyoxylic acids through radical-radical coupling. The reaction proceeds via a twofold SET-promoted Cu(I)/Cu(II) catalytic cycle under mild conditions. An analogous reaction variant allows for the N-acylation in a one-pot fashion directly starting from a secondary cyclic amine even in the presence of a second amine or hydroxy group.

Visible-Light-Mediated Efficient Metal-Free Catalyst for α-Oxygenation of Tertiary Amines to Amides

A metal-free system has been discovered for the efficient α-oxygenation of tertiary amines to the corresponding amides using oxygen as an oxidant. This visible-light-mediated oxygenation reaction exhibited excellent substrates scope under mild reaction conditions and generated water as the only byproduct. The synthetic utility of this approach has been demonstrated by applying onto drug molecules. At the end, detailed mechanistic reactions clearly showed the role of oxygen and the photocatalyst.

SeO2mediated efficient synthesis of amides and α-ketoamides of secondary amines with wide substrate scope

SeO2mediated oxidative amidation of acetophenones, phenylacetylenes, and phenylacetaldehydes to α-ketoamides and aldehydes to amides is reported. Amidation selectively proceeds with secondary amines. α-Ketoamide derivatives of natural products 16-dehydropregnenolone acetate (8), pregnenolone acetate (10), and progesterone (11) were synthesized.