83573-60-8

Upstream product

• 92-52-4 biphenyl 
• 122-01-0 4-chloro-benzoyl chloride 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 104-88-1 4-chlorobenzaldehyde 
• 1679-18-1 4-Chlorophenylboronic acid 
• 1591-31-7 4-iodo-biphenyl 
• 74-11-3 para-chlorobenzoic acid 

Downstream Products

• 30203-86-2 4-[(4-chlorophenyl)methyl]biphenyl 
• 1421320-28-6 4'-phenyl-4-mercapto benzophenone 
• 82361-64-6 biphenyl-4-yl-(4-chloro-phenyl)-phenyl-methane 

Relevant academic research and scientific papers

Carboxyboronate as a Versatile In Situ CO Surrogate in Palladium-Catalyzed Carbonylative Transformations

The application of carboxy-MIDA-boronate (MIDA=N-methyliminodiacetic acid) as an in situ CO surrogate for various palladium-catalyzed transformations is described. Carboxy-MIDA-boronate was previously shown to be a bench-stable boron-containing building block for the synthesis of borylated heterocycles. The present study demonstrates that, in addition to its utility as a precursor to heterocycle synthesis, carboxy-MIDA-boronate is an excellent in situ CO surrogate that is tolerant of reactive functionalities such as amines, alcohols, and carbon-based nucleophiles. Its wide functional-group compatibility is highlighted in the palladium-catalyzed aminocarbonylation, alkoxycarbonylation, carbonylative Sonogashira coupling, and carbonylative Suzuki–Miyaura coupling of aryl halides. A variety of amides, esters, (hetero)aromatic ynones, and bis(hetero)aryl ketones were synthesized in good-to-excellent yields in a one-pot fashion.

Pd-Catalyzed Suzuki–Miyaura Cross-Coupling of Arylboronic Acids and α-Iminonitriles through C–CN Bond Activation

A Pd-catalyzed Suzuki–Miyaura cross-coupling reaction between arylboronic acids and α-iminonitriles has been developed. The reaction proceeds through selective activation of the C–CN bond, tolerates a wide range of substituents, and delivers the versatile ketone products in moderate to excellent yields.

MERCAPTO-BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHODS THEREOF

The present invention provides a photocurable composition prepared using mercapto benzophenone compounds as key raw materials. The present invention aims to solve the problems existing in the prior photo-curing technology that low-molecular photoinitiator

Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof

The present invention provides a photocurable composition prepared using mercapto benzophenone compounds as key raw materials. The present invention aims to solve the problems existing in the prior photo-curing technology that low-molecular photoinitiator

Facile preparation of aromatic ketones from aromatic bromides and arenes with aldehydes

Aromatic ketones were efficiently prepared in good yields by the reactions of aryl bromides with n-BuLi, followed by the reactions with aromatic aldehydes or aliphatic aldehydes and the subsequent treatment with molecular iodine and K2CO3, in a one-pot method. The same treatment of arenes, instead of aromatic bromides, also provided the corresponding aromatic ketones in good yields. Using these methods, various diaryl ketones and alkyl aryl ketones bearing electron-rich aromatics and electron-deficient aromatics could be prepared efficiently by a simple, transition-metal-free, and therefore environmentally benign experimental procedure.

Synthesis of arylketones using Envirocat EPZG catalyst

The Friedel-Crafts acylation reactions of substituted benzene derivatives with substituted acid chlorides proceed smoothly in the presence of a catalytic amount of Envirocat EPZG, a novel supported reagent catalyst, based on montmorillonite K10 clay. This catalyst is eco-friendly, selective and reusable and hence provides a safer and a cost effective approach for large-scale production in industries. The present work involves synthesis of fifteen ketones by using fresh and reused Envirocat EPZG catalyst and a conventional catalyst for Friedel-Crafts reaction, anhyd. AlCl3. The yields of ketones with fresh Envirocat EPZG are always more than that obtained with anhyd. AlCl3. Envirocat EPZG has been reused for the number of reactions in a series, without much loss in its efficiency. Ketones having activating as well as deactivating groups on benzene ring have been synthesized in satisfactory yields.