83948-35-0

Basic information

• Product Name: 1-(4-METHOXY-PHENYL)-PROPYLAMINE
• Synonyms: TIMTEC-BB SBB009830;ART-CHEM-BB B028560;1-(4-METHOXYPHENYL)PROPAN-1-AMINE;1-(4-METHOXY-PHENYL)-PROPYLAMINE;AKOS B028560;1-(4-methoxyphenyl)propan-1-amine(SALTDATA: HCl)
• CAS NO: 83948-35-0
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.23
• Mol File: 83948-35-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 258.1°C at 760 mmHg
• Flash Point: 107.4°C
• Appearance: /
• Vapor Pressure: 0.014mmHg at 25°C
• CAS DataBase Reference: 1-(4-METHOXY-PHENYL)-PROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHOXY-PHENYL)-PROPYLAMINE(83948-35-0)
• EPA Substance Registry System: 1-(4-METHOXY-PHENYL)-PROPYLAMINE(83948-35-0)

Safety Data

• Hazardous Substances Data: 83948-35-0(Hazardous Substances Data)

Usage

General Description

1-(4-Methoxy-phenyl)-propylamine is a chemical compound also known as para-methoxyamphetamine (PMA). It is a synthetic drug that acts as a psychedelic and stimulant, closely related to amphetamine. PMA is known for its hallucinogenic effects and can produce feelings of euphoria, increased energy, and altered perception. However, it is also associated with dangerous side effects, including increased heart rate, elevated blood pressure, and potential risk of serotonin syndrome. PMA is classified as a Schedule I controlled substance in the United States due to its high potential for abuse and lack of accepted medical use.

InChI:InChI=1/C10H15NO/c1-3-10(11)8-4-6-9(12-2)7-5-8/h4-7,10H,3,11H2,1-2H3/p+1/t10-/m1/s1

Upstream product

• 5349-60-0 1-(4-methoxyphenyl)-1-propanol 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 121-97-1 4-Methoxypropiophenone 
• 123-11-5 4-methoxy-benzaldehyde 
• 10467-10-4 ethylmagnesium iodide 
• 536-44-7 4-(1-bromo-propyl)-anisole 
• 7664-41-7 ammonia 
• 10035-10-6 hydrogen bromide 
• 104-46-1 anethole 
• 64187-51-5 N-trimethylsilyl(4-methoxy)benzaldimine 
• 925-90-6 ethylmagnesium bromide 
• 24316-59-4 p-Methoxypropiophenone oxime 

Downstream Products

• 233608-13-4 1-(4-methoxyphenyl)propan-1-amine hydrochloride 
• 1255915-24-2 3-hydroxy-4-(2-(1-(4-methoxyphenyl)propylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylpicolinamide 
• 180698-57-1 1-Phthalimido-1-(4'-methoxyphenyl)propane 
• 235083-55-3 (R)-1-(4-methoxyphenyl)propan-1-amine 
• 208848-50-4 (S)-1-(p-methoxyphenyl)propan-1-amine 

Relevant articles and documents

Method for preparing primary amine by catalyzing reductive amination of aldehyde ketone compounds

The invention discloses a method for preparing primary amine by catalyzing reductive amination of aldehyde ketone compounds. The method comprises the following steps: 1) mixing nickel nitrate hexahydrate, citric acid and an organic solvent, carrying out heating and stirring until a colloidal material is obtained, drying the colloidal material, roasting the colloidal material in a protective atmosphere, pickling, washing and drying a roasted product, and performing a partial oxidation reaction on a dried product in an oxygen-nitrogen mixed atmosphere to obtain a catalyst for a reductive amination reaction; and 2) mixing aldehyde or ketone compounds, a methanol solution of ammonia and the reductive amination reaction catalyst, introducing hydrogen, and carrying out a reductive amination reaction. The method has the advantages of high primary amine yield, high selectivity, wide aldehyde ketone substrate range, short reaction time, mild reaction conditions, low cost, greenness, economicalperformance and the like; the used reductive amination reaction catalyst can be recycled more than 10 times, and the catalytic activity of the catalyst is not obviously changed in gram-level reactions; and the method is suitable for large-scale application.

Substituent effects on chiral resolutions of derivatized 1-phenylalkylamines by heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin GC stationary phase

Chiral resolutions of trifluoroacetyl-derivatized 1-phenylalkylamines with different type and position of substituent were investigated by capillary gas chromatography by using heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin diluted in OV-1701 as a chiral stationary phase. The influence of column temperature on retention and enantioselectivity was examined. All enantiomers of meta-substituted analytes as well as fluoro-substituted analytes could be resolved. Temperature had a favorable influence on enantioselectivity for small amines with substituents at the ortho-position. The type of substituent at the stereogenic center of amines also had a crucial effect as the ethyl group led to poor enantioseparation. Among all analytes studied, trifluoroacetyl-derivatized 1-(2′-fluorophenyl)ethylamine exhibited baseline resolution with the shortest analysis time.

Novel CRAC channel conditioning agent, and preparation method and applications thereof

The invention provides a novel CRAC (calcium release-activated calcium) channel conditioning agent, and a preparation method and applications thereof, and more specifically, the invention provides a compound represented by formula I, and the groups are defined in the patent specification. The invention also provides the preparation method of the compound represented by formula I, and applications of the compound as a CRAC channel conditioning agent.