84165-42-4

Basic information

• Product Name: 8-Benzyloxyquinoline
• Synonyms: 8-Benzyloxyquinoline
• CAS NO: 84165-42-4
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.28
• Mol File: 84165-42-4.mol
• Article Data: 17

Chemical Properties

• Melting Point: 118 °C
• Boiling Point: 397.9°C at 760 mmHg
• Flash Point: 144.3°C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 3.51E-06mmHg at 25°C
• Refractive Index: 1.648
• PKA: 3.31±0.17(Predicted)
• CAS DataBase Reference: 8-Benzyloxyquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Benzyloxyquinoline(84165-42-4)
• EPA Substance Registry System: 8-Benzyloxyquinoline(84165-42-4)

Safety Data

• Hazardous Substances Data: 84165-42-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H13NO/c1-2-6-13(7-3-1)12-18-15-10-4-8-14-9-5-11-17-16(14)15/h1-11H,12H2

Upstream product

• 123-75-1 pyrrolidine 
• 202259-06-1 8-(benzyloxy)-5-bromoquinoline 
• 110-91-8 morpholine 
• 1198-14-7 5-bromo-8-hydroxyquinoline 
• 100-39-0 benzyl bromide 
• 148-24-3 8-quinolinol 
• 100-51-6 benzyl alcohol 
• 104293-76-7 ethyl 8-hydroxyquinoline-5-carboxylate 
• 100-61-8 N-methylaniline 
• 110-89-4 piperidine 
• 100-44-7 benzyl chloride 
• 108-88-3 toluene 

Downstream Products

• 202259-06-1 8-(benzyloxy)-5-bromoquinoline 
• 63404-84-2 8-(benzyloxy)quinolin-2(1H)-one 

Relevant articles and documents

Method for catalyzing nitrogen heterocyclic ring aerobic dehydrogenation based on ionic liquid porous carbon material

The invention discloses a method for catalyzing nitrogen heterocycle aerobic dehydrogenation based on an ionic liquid porous carbon material, and is suitable for the field of organic synthesis. A heterogeneous catalysis system takes nitrogen heterocycle and derivatives thereof as substrates, a carbon material as a catalyst, water or ethanol as a solvent and air or oxygen spheres as an oxygen source, and a reaction is carried out at 0-80 DEG C under normal pressure, oxidative dehydrogenation of nitrogen heterocyclic compounds can be realized, and target products such as indole, quinoline, isoquinoline, quinazoline, quinoxaline, benzothiazole, Hanus ester and derivatives thereof and other medical intermediates can be synthesized. The non-metal catalyst is prepared by using the ionic liquid as the precursor, no activating agent or other additives are used in the reaction process, and the method has industrial application prospects.

Method for synthesizing aryl benzyl ether compound

The invention discloses a method for synthesizing aryl benzyl ether compounds, which comprises the following steps: by using an iron (III) complex containing 1, 3-di-tert-butyl imidazole cations and having a molecular formula of [(tBuNCH = CHNtBu) CH] [FeBr4] as a catalyst and di-tert-butyl peroxide as an oxidant, carrying out oxidative coupling reaction on phenolic compounds and toluene compounds to synthesize the corresponding aryl benzyl ether compounds. The method is the first example for preparing the aryl benzyl ether compound through the oxidative coupling reaction of the phenolic compound and the toluene compound, which is realized by an iron-based catalyst, and has the advantages of atom economy, environmental friendliness and good substrate applicability.

COMPOUNDS FOR THE INHIBITION OF UNREGULATED CELL GROWTH

The present invention discloses compounds for inhibition of uncontrolled cell proliferation particularly cancer stem cells. Particularly, the invention relates to compounds of Formula I to XXII for the treatment of cancer.